Scientist, In Vivo Pharmacology, Neuroscience

Bristol Myers Squibb; Cambridge (MA); Sur place; USD 130 000 - 157 000; Plein temps

Avantages offerts par ce poste

Flexible Time Off

11 company holidays

Stock opportunities

Résumé du poste

Bristol Myers Squibb in Cambridge is seeking a Scientist, In Vivo Pharmacology to advance neuroscience programs. You will perform and lead in vivo studies in mice, analyze PD readouts, and manage CRO partnerships, serving as a pharmacology representative on program teams.

Required is a PhD or equivalent in Life Sciences with 3+ years of experience; PhD in Neuroscience is highly preferred. The role offers a comprehensive benefits package and a flexible work model.

Qualifications

• PhD in Neuroscience or related field is preferred and required in some cases.
• Experience with rodent models and in vivo pharmacology techniques.
• Strong organizational and communication skills; ability to work independently or in a team.

Responsabilités

• Performs and directs in vivo pharmacology studies in mice, including dosing and tissue processing.
• Analyzes pharmacodynamic readouts such as mRNA/protein levels and neuropathology.
• Manages in vivo studies at CROs and represents the function on program teams.
• Contributes to experimental design and data interpretation within neuroscience programs.

Connaissances

In vivo pharmacology

Mouse handling

Molecular biology

Neuroscience

Formation

Bachelor's degree in Life Sciences

Master's degree in Life Sciences

Ph.D. or equivalent Life Sciences

Description du poste

At Bristol Myers Squibb, our employees often ask, “Who are you working for?”—a question that fuels collaboration, accountability, and urgency in our work. Our purpose-driven culture inspires us to discover, develop, and deliver innovative medicines to prevail over serious diseases. We offer uniquely interesting and meaningful work, opportunities for growth, and a supportive environment that values inclusion, wellbeing, flexibility, and comprehensive benefits. This is work that transforms the lives of patients, and the careers of those who do it.

The Neuroscience TRC is committed to the development of transformational therapeutics for patients with neurodegenerative, neuromuscular and neuropsychiatric diseases. A network of internal and external partnerships across neurodegenerative and neuropsychiatric diseases and treatment modalities (small molecules, biologics and genetic medicines) supports our ambition to become leaders in neuroscience. Internal research focuses on causal human biology, matching therapeutic modality to molecular mechanism, and translational discovery enabling a rapid path to clinical proof-of-concept.

In the role as a Scientist within In Vivo Pharmacology, the ideal candidate:

• Performs and directs in vivo pharmacology studies in mice, inclusive of in-life dosing (IV, SC, IP, PO, ICV), tissue collection, and tissue processing
• Performs and analyzes pharmacodynamic (PD) and efficacy readouts, including mRNA/protein expression levels, neuropathology, transcriptomics, and physiology.
• Manages in vivo studies conducted at contract research organizations (CROs)
• Serves as an in vivo pharmacology representative on program and platform teams

Basic Qualifications:

• Bachelor’s Degree
  • 5+ years of academic and / or industry experience

Or

• Master’s Degree
  • 3+ years of academic and / or industry experience

Or

• Ph.D. or equivalent advanced degree in the Life Sciences
  • No experience necessary

Preferred Qualifications:

• PhD in Neuroscience or related field is required.
• Expertise and practical experience in one or more of the following:
  • Neurodegenerative disease, such as Alzheimer’s Disease, Parkinson’s Disease, and Huntington’s Disease, particularly with respect to animal modeling
  • Neuromuscular disease, such as amyotrophic lateral sclerosis (ALS) and muscular dystrophies, particularly with respect to animal modeling
  • RNA biology and splice modulation
  • Genetic medicines, particularly the delivery of siRNAs and/or ASOs across the blood‑brain barrier (BBB)
• Extensive mouse handling experience, including common dosing routes and tissue collection from central nervous system (CNS) and peripheral tissues required
• Proficiency in standard molecular biology, biochemical, immunohistochemical, and/or muscle physiology assays required
• Experience with rodent stereotaxic surgery
• Familiarity with in vivo bioluminescence imaging
• Familiarity with transcriptomics and/or proteomics
• Experience working with contract research organization (CROs)
• Strong organizational and communication skills
• Ability to work independently and as part of a team
• Detail‑oriented with a commitment to scientific rigor and reproducibility
• Adaptability in a fast‑paced, collaborative research environment

We hire for skills and capabilities, not just credentials – if this role excites you, but doesn’t perfectly match your resume, we encourage you to apply anyway.

Compensation Overview:

Cambridge Crossing: $129,640 - $157,096

The starting pay range(s) listed above is for full‑time employees (FTE). You may also be eligible for additional discretionary incentive cash and stock opportunities. We determine starting pay thoughtfully – carefully considering the nature of the role, required skills, work location, schedule and the knowledge and experience you bring. Final compensation is guided by pay equity principles and applicable employment laws. Compensation programs are reviewed on an ongoing basis and may be adjusted over time to reflect evolving market factors, and individual, team or Company performance.

Benefits:

Subject to the terms and conditions of the applicable plans then in effect, you may be eligible to participate in our comprehensive benefit plans – including wellbeing support, retirement and financial protection benefits, and insurance offerings (medical, dental, vision, life and disability).

U.S.-based exempt employees are eligible for Flexible Time Off (FTO), which provides paid time off without a set accrual limit, subject to manager approval, along with 11 paid company holidays each year.

Non‑exempt employees, RayzeBio employees, and employees located in Puerto Rico receive 160 hours of paid vacation annually for new hires (subject to manager approval), 11 paid company holidays, and 3 optional holidays.

Depending on eligibility, employees may also have access to additional time‑off benefits, including paid sick leave, up to two paid volunteer days per year, summer hours flexibility, and leaves of absence for medical, personal, parental, caregiver, bereavement, or military needs. Eligible employees also enjoy an annual Global Shutdown between Christmas Day and New Year’s Day.

U.S.-based job seekers can explore full benefit offerings at https://careers.bms.com/benefits

How We Work

Where you work matters – because collaboration, innovation and patient impact happen in many settings. Our roles are structured across four work models: site-essential, site-by‑design, field‑based and remote‑by‑design. The model assigned to this role is based on its core responsibilities. Learn more at https://careers.bms.com/ways‑of‑working.

Supporting People with Disabilities

BMS is dedicated to ensuring that people with disabilities can excel through a transparent recruitment process, reasonable workplace accommodations/adjustments and ongoing support in their roles. Applicants can request a reasonable workplace accommodation/adjustment prior to accepting a job offer. If you require reasonable accommodations/adjustments in completing this application, or in any part of the recruitment process, direct your inquiries to [e-mail]. Visit careers.bms.com/eeo-accessibility to access our complete Equal Employment Opportunity statement.

Candidate Rights

BMS will consider qualified applicants with arrest and conviction records, pursuant to applicable laws in your area.

For roles based in Los Angeles County only: If you live in or expect to work from Los Angeles County if hired for this position, please visit this page for important additional information: https://careers.bms.com/california-residents/

Data Protection

We will never request payments, financial information, or social security numbers during our application or recruitment process. Learn more about protecting yourself at https://careers.bms.com/fraud-protection.

Any data processed in connection with role applications will be treated in accordance with applicable data privacy policies and regulations.

If this posting is missing required information required by local law or incorrect, contact BMS at [e-mail] the Job Title and Requisition number. Do not send application‑related inquiries to this email. To check your application status, please login to your Candidate Home Account.

R1607339 : Scientist, In Vivo Pharmacology, Neuroscience