Scientist - Molecular Biology, Cell Culture Upstream Process Development

BioSpace; Indianapolis (IN); On-site; USD 90,000 - 140,000; Full time

Benefits offered by this job

Company bonus

401(k)

Pension

Vacation benefits

Medical insurance

Dental insurance

Vision insurance

Prescription drug benefits

Flexible spending accounts

Life insurance

Death benefits

Employee assistance program

Fitness benefits

Job summary

BioSpace is seeking a scientist to lead upstream process development, focusing on cell line development and process optimization for bioproducts. The role supports transfers to manufacturing sites and prepares regulatory submission sections.

The candidate will have 3–6+ years of industrial experience in cell line generation, bioreactor operation, and recombinant protein expression, ensuring GMP/GLP compliance and high-quality data analysis for regulatory readiness.

Qualifications

• Requires a BS or MS in a biological or chemical engineering field with 3 to 6+ years of industrial experience.
• Hands-on experience in cell line generation, bioreactor operation, and recombinant protein expression.

Responsibilities

• Develop upstream process for cell line development and process optimization.
• Support process transfers to manufacturing sites.
• Author technical sections for regulatory submissions.

Skills

Cell Culture

Upstream Process Development

Cell Line Development

Bioreactor Operation

Recombinant Protein Expression

Experimental Design

Data Analysis

Regulatory Documentation

Process Scaling

Statistics

Data Science

AI/ML

GMP

GLP

Technical Troubleshooting

Molecular Biology

Education

BS in Biological or Chemical Engineering

MS in Biological or Chemical Engineering

Job description

The scientist is responsible for upstream process development activities, including cell line development and process optimization for bioproduct active pharmaceutical ingredients. They will support process transfers to manufacturing sites and author technical sections for regulatory submissions.

Requirements

Requires a BS or MS in a biological or chemical engineering field with 3 to 6+ years of industrial experience. Candidates must have hands‑on experience in cell line generation, bioreactor operation, and recombinant protein expression.

Key Skills

• Molecular Biology
• Cell Culture
• Upstream Process Development
• Cell Line Development
• Bioreactor Operation
• Recombinant Protein Expression
• Experimental Design
• Data Analysis
• Regulatory Documentation
• Process Scaling
• Statistics
• Data Science
• AI/ML
• GMP
• GLP
• Technical Troubleshooting

Benefits

• Company bonus
• 401(k)
• Pension
• Vacation benefits
• Medical insurance
• Dental insurance
• Vision insurance
• Prescription drug benefits
• Flexible spending accounts
• Life insurance
• Death benefits
• Employee assistance program
• Fitness benefits