Research Associate - Upstream Cell Culture

SPECTRAFORCE; Framingham (MA); On-site; USD 60,000 - 80,000; Full time

Job summary

A leading biotech company in Massachusetts is seeking a self-motivated and innovative Research Associate to join their Cell Culture Platform group. The role involves executing upstream cell culture experiments, collaborating with teams to optimize processes, and contributing to technical documentation. Ideal candidates have a relevant Bachelor's or Master's degree and lab experience. This position offers a chance to learn advanced cell culture techniques and significantly impacts early pipeline projects.

Qualifications

• Bachelor’s or master’s degree in a relevant discipline.
• 6+ months of experience through co-op or internships.
• Understanding of aseptic technique and principles of mammalian cell culture.

Responsibilities

• Plan and execute experiments for upstream cell culture processes.
• Collaborate with functional groups to support Phase I projects.
• Contribute to technical reports and experimental protocols.

Skills

Aseptic technique

Mammalian cell culture

Lab operations

Attention to detail

Quick learner

Education

Bachelor's or Master's degree in Chemical Engineering, Biochemical Engineering, Cell Biology, or Biochemistry

Job description

Overview

We are seeking a contract upstream Research Associate to join our Cell Culture Platform group in Cell Culture Development department (CCD-CCP). CCD-CCP is a global business unit responsible for the development of cell culture platforms including media and bioprocess technologies for both fed-batch and perfusion from early and late-stage biologics projects, as well as all upstream CMC development activities for early phase projects (up to Phase II).

The candidate will be self-motivated and strongly driven to succeed while demonstrating the ability to function well within a fast-paced and collaborative team-oriented environment. The candidate will also be inquisitive and innovative, exhibiting scientific curiosity and the ability to acquire new skills for fed-batch and perfusion based upstream cell culture processes.

This is an exciting opportunity to learn cutting-edge cell culture techniques and develop cell culture subject matter expertise. This role will have significant impacts on early pipeline projects, next generation cell culture process development and manufacturing strategies within the global network.

Responsibilities

• Require to be on site daily; Weekend work required occasionally.
• Plan and execute experiments to optimize upstream cell culture platform process at different scales (shake flasks, AMBR, 3L/10L bioreactors, etc.)
• Perform upstream experiments and collaborate with other functional groups to speed Phase I pipeline projects
• Contribute to technical reports, experimental protocols, and technical summaries for presentation internally and externally
• Participate in the technology transfer of processes into manufacturing facilities
• Ensure safety and environmental compliance are maintained in the workplace
• Some weekend working may be required for this role

Qualifications

Must Have Skills

• Bachelor’s or master’s degree in chemical engineering Biochemical Engineering, Cell Biology, Biochemistry or a related discipline
• Experience can include co-op or internships, 6+ months of experience
• Understanding of aseptic technique and principles of mammalian cell culture
• Lab operations experience
• Understanding of aseptic technique and principles of mammalian cell culture
• Some lab mammalian cell culture experience, however, microbial experience is not a match
• Quick learner for new techniques and technology
• Strong attention to details

Basic Qualifications

• Bachelor or Master’s degree in Chemical Engineering, Biochemical Engineering, Cell Biology, Biochemistry or a related discipline
• Post-education experience ≥3 years
• Understanding of aseptic technique and principles of mammalian cell culture
• Detailed in lab operations and quick learner for new technologies

Preferred Qualifications

• Up to 3 years of professional experience, or including internships
• Experience in the operation of fed-batch and/or perfusion-based cell culture bioreactors
• Knowledge of CMC
• Cell culture platform process at different scales (shake flasks, AMBR, 3L/10L bioreactors, etc.)
• Strong GPA is a plus