Scientist Medicinal Chemistry

Amgen SA; Thousand Oaks (CA); On-site; USD 90,000 - 130,000; Full time

Job summary

Amgen is seeking a passionate Scientist in Medicinal Chemistry to join a dynamic team aimed at innovating therapeutic solutions. The role involves designing and synthesizing new compounds, leveraging cutting-edge techniques such as NMR and mass spectral analysis, and ensuring rigorous safety and communication standards within a collaborative environment. This is a unique opportunity to contribute significantly to impactful biotech projects while enjoying a comprehensive benefits package.

Benefits

Comprehensive employee benefits package

Discretionary annual bonus program

Stock-based long-term incentives

Flexible work models

Qualifications

• Doctorate or equivalent experience in organic synthesis preferred.
• 2+ years lab experience with Master's or 4+ years with Bachelor's.
• Strong background in NMR and mass spectral techniques.

Responsibilities

• Design, synthesize, and purify novel compounds for drug development.
• Develop and execute organic chemistry reactions with troubleshooting.
• Maintain lab notebooks and participate in project meetings.

Skills

Communication

Leadership

Synthetic Chemistry

Troubleshooting

Teamwork

Education

Doctorate degree in chemistry

Master’s degree in chemistry

Bachelor’s degree in chemistry

Job description

HOW MIGHT YOU DEFY IMAGINATION?

You’ve worked hard to become the professional you are today and are now ready to take the next step in your career. How will you put your skills, experience and passion to work toward your goals? At Amgen, our shared mission—to serve patients—drives all that we do. It is key to our becoming one of the world’s leading biotechnology companies, reaching over 10 million patients worldwide. Come do your best work alongside other innovative, driven professionals in this meaningful role.

Scientist – Medicinal Chemistry

Live

What you will do

Let’s do this. Let’s change the world. In this vital role you be part of an innovative Medicinal Chemistry group with responsibilities including (but not limited to) the design, synthesis, and purification of novel compounds for potential clinical drug development. This will also include the opportunity to work within Amgen’s Induced Proximity Platform (IPP), which is focused on novel and innovative approaches to modulate intractable targets in diseases using the emerging PROTAC modality.

• The Scientist will work in teams to develop, implement and perform organic reactions for ongoing Medicinal Chemistry teams, including troubleshooting of synthetic routes and reactions, scouting of new synthetic routes and performing high difficulty synthetic chemistry.
• Furthermore, you will contribute to the design of new compounds and the development of structure-activity relationships.
• This individual will perform structural determinations using NMR and mass spectral techniques and purify compounds using a variety of techniques.
• They will be recognized as a lab leader and should demonstrate excellent verbal and written communication skills.
• Additional responsibilities include maintaining laboratory notebooks, participating in group and project meetings and, as needed, presenting to groups and aiding in the writing of papers and patent applications

Win

What we expect of you

We are all different, yet we all use our unique contributions to serve patients. The qualified professional we seek is a driven individual with these qualifications.

Basic Qualifications:

• Doctorate degree or
• Master’s degree and 2 years of laboratory experience OR
• Bachelor’s degree and 4 years of laboratory experience

Preferred Qualifications:

• Doctorate degree in chemistry specializing in organic synthesis by June 2025 OR 6+ years of focus or specialization in synthetic organic or medicinal chemistry (academic and/or industrial)
• Track record of accomplishments (e.g., peer-reviewed publications)
• Demonstrated ability to scout and troubleshoot synthetic routes, and perform high difficulty synthetic chemistry
• Clear understanding of structural determination using NMR and Mass Spectral techniques as well as knowledge of purification methods
• Demonstration of good lab practices, with particular attention to safety
• Excellent communication skills (both written and oral), leadership skills and the ability to work well in teams

Thrive

What you can expect of us

As we work to develop treatments that take care of others, we also work to care for our teammates’ professional and personal growth and well-being.

In addition to the base salary, Amgen offers a Total Rewards Plan comprising health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities including:

• Comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts.
• A discretionary annual bonus program, or for field sales representatives, a sales-based incentive plan
• Stock-based long-term incentives
• Award-winning time-off plans and bi-annual company-wide shutdowns
• Flexible work models, including remote work arrangements, where possible

Apply now

for a career that defies imagination

Objects in your future are closer than they appear. Join us.

careers.amgen.com

Amgen is an Equal Opportunity employer and will consider you without regard to your race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, or disability status.

We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation.