Scientist, Large Molecule Analytical (On-site)

MSD; Rahway (NJ); On-site; USD 87,000 - 137,000; Full time

Benefits offered by this job

Medical, dental, vision

401(k) retirement plan

Paid holidays

Vacation and sick days

Relocation assistance

Job summary

MSD in Rahway, NJ seeks a Scientist in the Large Molecule Analytical department. The role focuses on developing and transferring analytical methods for monoclonal proteins and complex biologics in a fast-paced, collaborative environment.

The candidate should have a laboratory background with experience in UPLC/HPLC, PCR/ELISA, and data interpretation. Collaborative cross-functional work and potential publication of findings are expected, with opportunities for professional growth and involvement

Qualifications

• BA/BS in analytical chemistry/biochemistry or related field with a minimum of 3 years of experience in the Pharmaceutical Industry
• MS with a minimum of 0+ year relevant experience (with expected graduation no later than January 2027)
• Prior experience in a laboratory environment
• Ability to develop and apply basic principles and scientific concepts to execute work in a laboratory setting
• Execute routine experiments and data interpretation with appropriate technical guidance
• Ability to operate and troubleshoot analytical methods
• Understanding of the fundamentals in separations science
• Experience with UPLC/HPLC analysis of biologics (e.g., SEC, RP, IEX) and CE techniques or molecular biology (PCR, DNA extraction) and immunoassay (ELISA, gel electrophoresis) techniques
• Ability to work within overall project timelines to manage prioritization and execution of individual deliverables with appropriate supervision
• Demonstrated experience working within collaborative team environments
• Experience in authoring and reviewing internal technical reports, sections of regulatory filings (e.g., IND, BLA) and external scientific publications

Responsibilities

• Develop, qualify, implement, troubleshoot, and transfer analytical methods for monoclonal proteins or complex biologics.
• Collaborate in fast-paced, multidisciplinary teams to enable biologics development.
• Publish findings and contribute to regulatory filings and external publications.
• Interpret data and operate with laboratory informatics to support project timelines.
• Author internal technical reports and participate in method transfers and documentation

Skills

Laboratory experience

Analytical methods

Separation science

UPLC/HPLC for biologics

PCR/ELISA

Project management

Technical reporting

Education

BA/BS in analytical chemistry/biochemistry or related field

MS with relevant experience (graduation by Jan 2027)

Tools

RLIMS

ELN

Empower

Microsoft Office

Job description

Role Decription:

The Large Molecule Analytical department of our Research & Development Division is seeking applicants for a Scientist position. The Scientist is a laboratory-based scientific role tasked with solving complex analytical problems at the interface of biology, chemistry, and lab informatics disciplines to enable development of Biologics drug substances and drug products. The successful candidate must function well and be able to collaborate in a fast-paced, integrated, multidisciplinary team environment. The qualified candidate will be responsible for development, qualification, implementation, troubleshooting and transfer of analytical methods for monoclonal proteins or other complex therapeutic proteins. Applicants must have effective organizational, multi-tasking, oral/written communications skills, show scientific leadership, and a desire to conduct research and publish. Evidence of strong cross-functional collaboration in an academic or industrial setting is also preferred.

Education:

• BA/BS in analytical chemistry/biochemistry or related field with a minimum of 3 years of experience in the Pharmaceutical Industry, or
• M.S. with a minimum of 0+ year relevant experience (with expected graduation no later than January 2027).

Required Experience and Skills:

• Prior experience in a laboratory environment
• Ability to develop and apply basic principles and scientific concepts to execute work in a laboratory setting
• Execute routine experiments and data interpretation with appropriate technical guidance
• Ability to operate and troubleshoot analytical methods
• Understanding of the fundamentals in separations science
• Experience with UPLC/HPLC analysis of biologics (e.g., SEC, RP, IEX) and CE techniques or molecular biology (PCR, DNA extraction) and immunoassay (ELISA, gel electrophoresis) techniques
• Ability to work within overall project timelines to manage prioritization and execution of individual deliverables with appropriate supervision
• Demonstrated experience working within collaborative team environments
• Experience in authoring and reviewing internal technical reports, sections of regulatory filings (e.g., IND, BLA) and external scientific publications

Preferred Experience and Skills:

• Past experience working as part of a project team
• Strong knowledge of protein structure and degradation pathways
• Experience in analysis of various Biologic modalities (e.g., mAb, antibody-drug conjugate, fusion protein)
• Background in Analytical Methodologies and sound scientific understanding of Critical Quality Attributes/QbD/DOE principles
• Prior experience with Microsoft Office and other research applications (e.g., RLIMS, ELN, Empower)
• Experience in data analytics, programming, or laboratory automation

Required Skills:

Analytical Chemistry, Analytical Development, Biological Analysis, Biologics, Cell-Based Assays, DNA Extractions, Good Manufacturing Practices (GMP), Immunoassays, Laboratory Automation, Laboratory Information Management System (LIMS), Laboratory Techniques, Mammalian Cell Culture, Real Time Polymerase Chain Reaction (qPCR), Standard Operating Procedure (SOP) Writing

US and Puerto Rico Residents Only:

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The primary location for this posting is: USA - New Jersey - Rahway

Where required by law, the compensation range for this role is provided below.

The salary range for the primary location of this role is: $87,300.00 - $137,400.00

This range reflects the Company's reasonable expectation of the base salary applicable to this role at the time of posting. An employee’s position within the salary range will be based on several factors including, but not limited to relevant education, qualifications, certifications, experience, skills, geographic location, government requirements, and business or organizational needs. The successful candidate will be eligible for annual bonus and long-term incentive, if applicable.

We offer a comprehensive package of benefits. Available benefits include medical, dental, vision healthcare and other insurance benefits (for employee and family), retirement benefits, including 401(k), paid holidays, vacation, and compassionate and sick days. More information about benefits is available at https://jobs.merck.com/us/en/compensation-and-benefits.

Additional location(s): Please note the salary range above applies to the Primary Location of the position. Where a role has other listed locations, different compensation guidelines may apply. You may find the salary ranges for additional locations below. If the salary range is not listed for the location you are applying to, our Talent Acquisition team will provide further information to you relevant to your location.

Additional location(s) Compensation Information:

• San Francisco Residents Only: We will consider qualified applicants with arrest and conviction records for employment in compliance with the San Francisco Fair Chance Ordinance
• Los Angeles Residents Only: We will consider for employment all qualified applicants, including those with criminal histories, in a manner consistent with the requirements of applicable state and local laws, including the City of Los Angeles’ Fair Chance Initiative for Hiring Ordinance

Employee Status: Regular

Relocation: Domestic

VISA Sponsorship: No

Travel Requirements: 10%

Flexible Work Arrangements: Not Applicable

Shift: 1st - Day

Valid Driving License: No

Hazardous Material(s): n/a

Job Posting End Date: 11/3/2026