Scientist, Large Molecule Analytical (On-site)

Merck & Co.; Rahway (NJ); On-site; USD 87,000 - 137,000; Full time

Job summary

Merck & Co. is seeking a Scientist in the Large Molecule Analytical department in Rahway, NJ.

The role focuses on solving complex analytical problems at the interface of biology, chemistry, and lab informatics to enable development of biologics drug substances and products. The successful candidate will develop, qualify, implement, troubleshoot and transfer analytical methods for monoclonal proteins or other complex therapeutic proteins, collaborating in a fast-paced, integrated team environment

Qualifications

• BA/BS in analytical chemistry/biochemistry or related field with 3+ years in the pharmaceutical industry

Responsibilities

• Develop, qualify, implement, troubleshoot and transfer analytical methods for monoclonal proteins or complex biologics
• Collaborate in a fast-paced, multidisciplinary team environment
• Author and review internal technical reports and sections of regulatory filings (IND, BLA)
• Publish scientific work and communicate across functions

Skills

Laboratory experience

Analytical methods

Data interpretation

UPLC/HPLC

CE techniques

Molecular biology

Project timelines

Cross-functional collaboration

Technical reporting

Education

BS in analytical chemistry or biochemistry

MS with relevant experience

Tools

RLIMS

ELN

Empower

Microsoft Office

Job description

Job Description

Role Decription:

The Large Molecule Analytical department of our Research & Development Division is seeking applicants for a Scientist position. The Scientist is a laboratory-based scientific role tasked with solving complex analytical problems at the interface of biology, chemistry, and lab informatics disciplines to enable development of Biologics drug substances and drug products. - The successful candidate must function well and be able to collaborate in a fast-paced, integrated, multidisciplinary team environment. - The qualified candidate will be responsible for development, qualification, implementation, troubleshooting and transfer of analytical methods for monoclonal proteins or other complex therapeutic proteins. -Applicants must have effective organizational, multi-tasking, oral/written communications skills, show scientific leadership, and a desire to conduct research and publish. -Evidence of strong cross-functional collaboration in an academic or industrial setting is also preferred.

Qualifications:

Education:

• BA/BS in analytical chemistry/biochemistry or related field with a minimum of 3 years of experience in the Pharmaceutical Industry, or
• M.S. with a minimum of 0+ year relevant experience (with expected graduation no later than January 2027).

Required Experience and Skills:

• Prior experience in a laboratory environment
• Ability to develop and apply basic principles and scientific concepts to execute work in a laboratory setting
• Execute routine experiments and data interpretation with appropriate technical guidance
• Ability to operate and troubleshoot analytical methods
• Understanding of the fundamentals in separations science
• Experience with UPLC/HPLC analysis of biologics (e.g., SEC, RP, IEX) and CE techniques or molecular biology (PCR, DNA extraction) and immunoassay (ELISA, gel electrophoresis) techniques
• Ability to work within overall project timelines to manage prioritization and execution of individual deliverables with appropriate supervision
• Demonstrated experience working within collaborative team environments
• Experience in authoring and reviewing internal technical reports, sections of regulatory filings (e.g., IND, BLA) and external scientific publications

Preferred Experience and Skills:

• Past experience working as part of a project team
• Strong knowledge of protein structure and degradation pathways
• Experience in analysis of various Biologic modalities (e.g., mAb, antibody-drug conjugate, fusion protein)
• Background in Analytical Methodologies and sound scientific understanding of Critical Quality Attributes/QbD/DOE principles
• Prior experience with Microsoft Office and other research applications (e.g., RLIMS, ELN, Empower)
• Experience in data analytics, programming, or laboratory automation

#EligibleforERP

Required Skills:

Analytical Chemistry, Analytical Development, Biological Analysis, Biologics, Cell-Based Assays, DNA Extractions, Good Manufacturing Practices (GMP), Immunoassays, Laboratory Automation, Laboratory Information Management System (LIMS), Laboratory Techniques, Mammalian Cell Culture, Real Time Polymerase Chain Reaction (qPCR), Standard Operating Procedure (SOP) Writing

US and Puerto Rico Residents Only:

Our company is committed to inclusion, ensuring that candidates can engage in a hiring process that exhibits their true capabilities.

As an Equal Employment Opportunity Employer, we provide equal opportunities to all employees and applicants for employment and prohibit discrimination on the basis of race, color, age, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability status, or other applicable legally protected characteristics.--As a federal contractor, we comply with all affirmative action requirements for protected veterans and individuals with disabilities.- For more information about personal rights under the U.S. Equal Opportunity Employment laws, visit:

• EEOC Know Your Rights
• EEOC GINA Supplement

We are proud to be a company that embraces the value of bringing together, talented, and committed people with diverse experiences, perspectives, skills and backgrounds. The fastest way to breakthrough innovation is when people with diverse ideas, broad experiences, backgrounds, and skills come together in an inclusive environment. We encourage our colleagues to respectfully challenge one another's thinking and approach problems collectively.

Learn more about your rights, including under California, Colorado and other US State Acts

The primary location for this posting is:

USA - New Jersey - Rahway

Additional location(s):

Where required by law, the compensation range for this role is provided below.

The salary range for the primary location of this role is:

$87,300.00 - $137,400.00

This range reflects the Company's reasonable expectation of the base salary applicable to this role at the time of posting. An employee's position within the salary range will be based on several factors including, but not limited to relevant education, qualifications, certifications, experience, skills, geographic location, government requirements, and business or organizational needs. The successful candidate will be eligible for annual bonus and long-term incentive, if applicable.

We offer a comprehensive package of benefits. Available benefits include medical, dental, vision healthcare and other insurance benefits (for employee and family), retirement benefits, including 401(k), paid holidays, vacation, and compassionate and sick days. More information about benefits is available at https://jobs.merck.com/us/en/compensation-and-benefits .

Additional location(s) Compensation Information:

San Francisco Residents Only:

We will consider qualified applicants with arrest and conviction records for employment in compliance with the San Francisco Fair Chance Ordinance

Los Angeles Residents Only:

We will consider for employment all qualified applicants, including those with criminal histories, in a manner consistent with the requirements of applicable state and local laws, including the City of Los Angeles' Fair Chance Initiative for Hiring Ordinance

Employee Status:

Regular

Relocation:

Domestic

VISA Sponsorship:

No

Travel Requirements:

10%

Flexible Work Arrangements:

Not Applicable

Shift:

1st - Day

Valid Driving License:

No

Hazardous Material(s):

n/a

Job Posting End Date:

11/3/2026

*A job posting is effective until 11:59:59PM on the day BEFORE -the listed job posting end date. Please ensure you apply to a job posting no later than the day BEFORE the job posting end date.

Requisition ID:

R423136