Scientist II, Radiochemistry

Radionetics Oncology, Inc.; San Diego (CA); On-site; USD 130,000 - 160,000; Full time

Job summary

An innovative company in the oncology sector is seeking a Scientist II in Radiochemistry to join their dynamic Research and Development team. This role involves hands-on work with radioconjugate profiling and synthesis, utilizing cutting-edge techniques to develop novel radiopharmaceuticals for solid tumors. The ideal candidate will be a technical expert in radiochemistry with a strong background in laboratory practices and data analysis. You will collaborate with a talented team of scientists, contributing to critical projects that aim to advance cancer treatment. This is a unique opportunity to make a significant impact in a field with high unmet medical needs.

Benefits

Medical Insurance

Dental Insurance

Vision Insurance

401(k) Retirement Plan

Paid Time Off (PTO)

Generous Paid Holidays

Bonus Opportunity

Equity Options

Life Insurance

Short-term and Long-term Disability Insurance

Qualifications

• 2+ years of hands-on experience with radiochemistry.
• Experience with radiochemistry synthesis, purification, and formulation.

Responsibilities

• Develop radiochemistry methods using radioisotopes.
• Produce radioconjugate batches for in vivo studies.
• Analyze and interpret radiochemistry data.

Skills

Radiochemistry

Formulation Development

Data Analysis

Laboratory Techniques

Communication Skills

Education

Ph.D. in Chemistry or Related Field

Master's Degree with Relevant Experience

Tools

HPLC

iTLC

Dose Calibrator

Job description

About Radionetics
Radionetics Oncology, Inc. is a clinical stage company focused on the discovery and development of novel radiopharmaceuticals for the treatment of a wide range of oncology indications and is poised to capitalize on the increasing demand for novel radiotherapeutics. Radionetics Oncology is supported by Frazier Life Sciences, 5AM Ventures, DCVC Bio, Crinetics Pharmaceuticals, and GordonMD Global Investments and has entered into a strategic agreement with Eli Lilly. Radionetics is advancing a pipeline of first-in-class small molecule radioligands targeting G protein coupled receptors for the treatment of a broad range of cancers, including breast cancer, lung cancer, and other indications of high unmet need. For more information, visit https://radionetics.com.

Position summary
The Scientist II, Radiochemistry (Sci II) is a dynamic and hands-on member of the Research and Development organization that supports in vivo and in vitro radioconjugate profiling and candidate selection for the development of radiopharmaceuticals for solid tumors. The Sci II is a technical expert in synthesis of radioconjugates , quality control analysis of the conjugates for in vivo and in vitro studies, stability (e.g. radiolysis) and other in vitro assays, and related data analysis. The Sci II is well versed in handling of radioisotopes such as Ga-68, In-111, Lu-177 and others related to radioconjugation method development and routine productions, formulation development and assessments to support downstream in vivo and in vitro studies. The Sci II is an integral member of a team of highly skilled scientists with diverse skill sets. The Sci II is a key member supporting the Biology team in presenting results and participating in cross-functional teams to develop innovative solutions that drive forward multiple discovery programs in parallel. The Sci II will also support the Technical Operations team in matters related to production of radioconjugates to support clinical needs.

Essential job functions and duties

• After safety training, radioactive materials handling, including adherence to related safety.
• Radiochemistry and formulation method development using various radioisotopes including but not limited to In-111, Lu-177 and Ga-68.
• Routine productions of radioconjugate batches to support in vivo and in vitro studies (eg. biodistribution studies in animal models).
• Formulation development and stability assessment to support downstream development and clinical efforts.
• Support the Technical Operations team with the production of radioconjugates to support clinical needs.
• Oversight maintenance and calibration of all radiochemistry lab equipment (e.g. fume hood, HPLCs, iTLC, dose calibrator and general chemistry equipment).
• Interpret radiochemistry data, recognize aberrant results and propose explanations, potential solutions and next steps
• Independently analyze data using specialized software programs.
• Summarize data for reports and presentations.
• Authoring radiochemistry reports to support regulatory submissions.
• Interpret and present data to internal teams.
• Maintain electronic lab notebooks and any other required recordkeeping.
• Maintain a work environment focused on scientific integrity and quality.
• Perform other duties as required by business needs.

Minimum required qualifications

• Ph.D. in chemistry, or related field, or a Master’s degree with relevant experience.
• Minimum 2 years of hands-on experience with radiochemistry.
• Experience with laboratory techniques such as radiochemistry synthesis, purification, and formulation.
• Excellent communication, interpersonal, and organizational skills.
• Ability to work independently and manage multiple projects simultaneously.
• Ability and willingness to work with radioactive isotopes.
• Preferred qualifications
• Experience with theranostics and radiometals conjugation using common chelators.
• Experience with common theranostic radioisotopes including In-111, Lu-177, Ga-68 and Ac-225 is a plus.

Non-standard work schedule, travel or environmental requirements
The position is based on-site in San Diego, CA.

Compensation & Benefits
Radionetics has a competitive total compensation package that includes bonus opportunity; equity; medical, dental, vision, life, short-term, and long-term disability insurance; 401(k) retirement plan; 4 weeks of paid time off (PTO) annually; and generous paid holidays.

Pay Range: $130,000 – 160,000
Radionetics evaluates a variety of factors in determining individual pay decisions, which may include relevant education, experience, and skills; internal equity; complexity and responsibility of the role; and market demand relative to the position. Geographic location may also be a consideration in evaluating salary when candidates work in states outside of California.

Important notices
Radionetics Oncology, Inc. is committed to a policy of equal opportunity in which all qualified applicants receive equal consideration for employment without regard to race, color, national origin, ancestry, religion, sex, pregnancy, marital status, sexual orientation, gender, gender identity and expression, age, physical and medical disability, medical condition, genetic information, military or veteran status, or any other federal, state or local protected class.

The job description specifics provided above are intended to describe the general nature and level of work performed by people assigned to this classification. They are not intended to be construed as an exhaustive list of all responsibilities and requirements. Radionetics retains the right to add or change duties, education, experience, skills or any other requirements of the position at any time.
Radionetics does not accept unsolicited referrals from employment agencies for position vacancies unless written authorization is provided from the Human Resources department before any candidates are referred for specific identified positions. In the absence of such written authorization, any actions taken by the employment business/agency shall be deemed to have been performed without consent or contractual agreement, and Radionetics shall not be liable for any fees arising from such actions or referrals for position vacancies at Radionetics.