Cheminformatics Scientist

Altos Labs; San Diego (CA); On-site; USD 138,000 - 221,000; Full time

Job summary

A leading company in biotechnology is seeking a Cheminformatics Scientist to enhance drug discovery efforts. The role involves designing and optimizing cheminformatics tools, collaborating with various scientific teams, and contributing to innovative therapeutic projects. Candidates should have a Ph.D. or relevant experience with strong programming skills and a passion for scientific excellence.

Qualifications

• Ph.D. in Chemistry or Cheminformatics with relevant experience.
• Expertise in cheminformatics principles and techniques.

Responsibilities

• Support project teams with cheminformatics expertise.
• Develop tools for data query, extraction, and interpretation.
• Collaborate on computational chemistry and ML tools.

Skills

Cheminformatics

Data Analysis

Python

Communication

Education

Ph.D. in Chemistry

Ph.D. in Cheminformatics

Tools

KNIME

Spotfire

Pandas

Matplotlib

RDKit

Job description

Our Mission

Our mission is to restore cell health and resilience through cell rejuvenation to reverse disease, injury, and the disabilities that can occur throughout life.

Diversity at Altos

We believe that diverse perspectives are foundational to scientific innovation and inquiry. At Altos, exceptional scientists and industry leaders from around the world work together to advance a shared mission. Our intentional focus is on Belonging, so that all employees know that they are valued for their unique perspectives. We are all accountable for sustaining a diverse and inclusive environment.

What You Will Contribute To Altos

Altos Labs is seeking a highly qualified Cheminformatics Scientist to join the Chemistry and DMPK Drug Discovery team. This individual contributor role will play a crucial role in advancing our drug discovery efforts by designing, implementing, and optimizing cheminformatics and machine learning tools for small molecules and antisense oligonucleotides. The successful candidate will collaborate extensively with Medicinal Chemists, DMPK scientists, Biologists and IT/informatics colleagues to support molecular design and data analysis.

Responsibilities

• Support project teams by providing cheminformatics expertise and contributing to data interpretation and decision-making.
• Develop and implement tools and workflows to enable data query, extraction, interpretation, and SAR.
• Collaborate with colleagues in computational chemistry to develop and support cutting-edge computational chemistry and ML tools for small molecule design by leveraging commercial and proprietary software.
• Build and maintain tools to support the design and analysis of oligonucleotides.
• Where appropriate, develop and maintain cheminformatics codebases, ensuring their reliability and performance

Who You Are

We are seeking highly motivated, creative, and collaborative individuals who are passionate and dedicated to employing their expertise to restore cell health and reverse disease. This position will be part of a multidisciplinary team within the IOM that will develop novel therapeutic projects and pipelines at Altos. The candidate will work in a highly dynamic and cross-functional environment that requires collaboration with the Institutes of Science and will span multiple therapeutic areas and therapeutic modalities. The successful candidate will have strong scientific training and experience in the biotechnology or pharmaceutical industry.

Minimum Qualifications:

• Ph.D. in Chemistry, Cheminformatics, or a related field with 0-3 years post-Ph.D. Non PhDs with at least 8 years of relevant experience will be considered.
• Demonstrated expertise in cheminformatics principles and techniques
• Experience in informatics and computational chemistry. Proficiency in data processing, analysis, and visualization software (e.g., KNIME, Spotfire)
• Strong programming skills in Python for data analysis, visualization, and tool development, including experience with relevant libraries such as Pandas, Matplotlib, and RDKit
• Excellent organization and communication with effective presentation skills

Preferred Qualifications:

• Experience in training and deploying ML models is preferred
• Experience working with cheminformatics databases is preferred
• Basic understanding of chemistry and medicinal chemistry concepts

Culture & Team Fit:

• Ability to work collaboratively across multiple groups within the organization
• Self-driven and enthusiastic with proficiencies to deliver in a dynamic environment
• Curious mindset with a willingness and flexibility to learn new skills
• High level of creativity and productivity with strong problem-solving skills

We are open to considering candidates in either our Redwood City or our San Diego location. The full salary ranges by location and level are below.

The salary range for Redwood City, CA:

• Scientist I: $ 148,750 - $201,250
• Scientist II: $175,000 - $ 252,000
• Senior Scientist I: $ 210,000 - $ 280,800
• Senior Scientist II:$ 234,000 - $ 312,000

The salary range for San Diego, CA:

• Scientist I: $138,550 - $187,450
• Scientist II: $163,000 - $ 220,800
• Senior Scientist I: $ 184,000 - $ 255,600
• Senior Scientist II:$ 213,000 - $ 297,600

Exact compensation may vary based on skills, experience, and location.

- Please click here to read the Altos Labs EU and UK Applicant Privacy Notice (bit.ly/eu_uk_privacy_notice )
- This Privacy Notice is not a contract, express or implied and it does not set terms or conditions of employment.

What We Want You To Know

We are a culture of collaboration and scientific excellence, and we believe in the values of inclusion and belonging to inspire innovation.

Altos Labs provides equal employment opportunities to all employees and applicants for employment and prohibits discrimination and harassment of any type without regard to race, color, religion, age, sex, national origin, disability status, genetics, protected veteran status, sexual orientation, gender identity or expression, or any other characteristic protected by federal, state or local laws.

This policy applies to all terms and conditions of employment, including recruiting, hiring, placement, promotion, termination, layoff, recall, transfer, leaves of absence, compensation and training.

Altos currently requires all employees to be fully vaccinated against COVID-19, subject to legally required exemptions (e.g., due to a medical condition or sincerely-held religious belief).

Thank you for your interest in Altos Labs where we strive for a culture of scientific excellence, learning, and belonging.

Note: Altos Labs will not ask you to download a messaging app for an interview or outlay your own money to get started as an employee. If this sounds like your interaction with people claiming to be with Altos, it is not legitimate and has nothing to do with Altos. Learn more about a common job scam at https://www.linkedin.com/pulse/how-spot-avoid-online-job-scams-biron-clark/

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