Scientist - II

LanceSoft Inc; Cambridge (MA); On-site; Full time

Job summary

LanceSoft Inc is seeking a Scientist - II for their Neuroimmunology team in Cambridge, MA. The ideal candidate will have a strong background in CNS cell biology, capable of conducting functional assays and delivering data collaboratively. A BS/BA in relevant fields and 2+ years of experience are required. This role offers a competitive hourly pay range and a chance to contribute to neurodegenerative disease research.

Qualifications

• Minimum 2+ years of industry or academic experience required.
• Strong knowledge in sterile techniques and immortalized cell lines.

Responsibilities

• Develop and perform cell-based functional assays.
• Communicate data to teams and stakeholders effectively.
• Collaborate across functional teams in genetics and pharmacology.

Skills

Cell culture methods

Data analysis

Critical thinking

Immunofluorescence

Molecular profiling techniques

Education

BS/BA in Biology, Neuroscience, Molecular Biology, Bioengineering, or Biotechnology

Job description

Title: Scientist - II

Location: Cambridge, MA

Contract Duration: 12 Months

Pay Range: $38.00 - $44.30 USD hourly on W2

Job Description:

Scientist–Neuroimmunology: The Neuroimmunology team is seeking a motivated and technically skilled individual with strong CNS cell biology skills to join our Cambridge-based team. Candidates will collaborate with colleagues across diverse functional areas including genetics, chemical biology, immunology, and pharmacology. Primary responsibilities include culturing of stable cell lines, primary and iPS-derived microglia to support the study of disease-associated functions and phenotypes that will aid in the identification and validation of therapeutic targets for neurodegenerative diseases.

The responsibilities of the Neuroimmunology team member include:

• Assist in developing and performing disease-relevant cell-based functional assays.
• Perform high content imaging, biochemical, and molecular profiling techniques.
• Communicate data clearly and concisely to teams and stakeholders.
• Thrive in a team environment.

Qualifications — Education and Experience:

BS/BA degree in Biology, Neuroscience, Molecular Biology, Bioengineering, Biotechnology, or equivalent, with at least 2+ years of industry or academic experience.

Required Skills and Competencies:

• Strong knowledge of cell culture methods and sterile techniques.
• Experience working with immortalized cell lines, primary rodent neurons and glia (e.g., microglia), and human iPS-derived CNS cell models including microglia and neurons.
• Understanding of standard cell transfection techniques using lipid-based and electroporation methods.
• Proficiency in cell staining methods including immunofluorescence and structural staining.
• Experience with method optimization, troubleshooting, and critical thinking skills.
• Proven experience in image acquisition, microscopy, and a working knowledge of mouse neuroanatomy.
• Ability to work independently on data analysis with practical knowledge of statistics.

Preferred Skills:

• Experience with plate-based high content imaging microscopy and live cell imaging.
• Demonstrated experience with quantitative image analysis.
• Understanding of biochemical and molecular biology techniques including protein and RNA extraction, western blot, ELISA, and qPCR.
• Experience with cellular signaling and functional studies such as phagocytosis and cell motility.
• Strong oral, written, and presentation skills to communicate concepts clearly in lab and team settings.