Scientist I, Assay Productization for NGS & Single-Cell

Neara; Pleasanton (CA); On-site; USD 90,000 - 120,000; Full time

Job summary

Neara seeks a Scientist I to join the Assay Productization team, supporting development and commercial launch of new Single Cell Genomic products. You will work with R&D and Production to develop and validate reagents across the 10x portfolio, independently applying scientific expertise to deliver key AP outcomes.

You will design experiments, manage documentation, and communicate results to stakeholders in a fast-paced environment, driving troubleshooting and process improvements with minimal

Qualifications

• BS in molecular biology or related field with 5+ years experience; MS with 3+ years; or PhD with 1+ year.
• Hands-on experience with NGS library generation and sequencing workflows.
• Prior work in a process or product development role, including technology transfer to manufacturing and/or QC groups.
• Strong understanding of molecular biology fundamentals and reagent or assay development.
• Proficiency with analytical techniques including qPCR, HPLC, Enzymatic Assays, and instruments such as Bioanalyzers or Fragment Analyzers.
• Ability to independently design, execute, analyze, and interpret multi-step experiments with diligent planning and record keeping.
• Experience troubleshooting molecular biology-based assays and identifying root causes of failures.
• Familiarity with manufacturing documentation systems and quality processes (batch records, ECOs, or equivalent).
• Strong collaboration and communication skills across scientific and operational teams.
• Self-motivated with the ability to manage and prioritize work independently in a fast-paced environment.

Responsibilities

• Independently execute and design experiments, including NGS library preparation from single cells, tissues, or isolated DNA/RNA using 10x instruments and consumables.
• Draft, maintain, and update manufacturing readiness documentation, including production batch records, without assistance.
• Optimize and refine QC methods and assays to assess reagent quality through a variety of analytical and functional tests.
• Own AP deliverables end-to-end for low complexity projects, and contribute to complex projects under guidance from an AP lead.
• Perform troubleshooting of failed experiments and reagent issues as they arise, identifying root cause and determining best course of action.
• Support reagent guard banding and stability studies.
• Update parts and shelf-life documentation, including Part Specifications and Receiving Inspection Records via ECOs.
• Facilitate handoffs from R&D to Operations by training QC and Production staff on new workflows and methods.
• Present experimental data and results clearly to internal stakeholders, with well-reasoned interpretation and analysis.
• Communicate identified risks appropriately and proactively, and collaborate cross-functionally to resolve issues.

Skills

NGS library prep

Data analysis

Molecular biology

Troubleshooting

QC expertise

Documentation

Cross-functional

Independence

Education

BS in molecular biology

MS in related field

PhD in related field

Tools

Bioanalyzer

Fragment Analyzer

qPCR

HPLC

Arena PLM/ERP

Job description

Neara seeks a Scientist I to join the Assay Productization team, supporting development and commercial launch of new Single Cell Genomic products. You will work with R&D and Production to develop and validate reagents across the 10x portfolio, independently applying scientific expertise to deliver key AP outcomes.

You will design experiments, manage documentation, and communicate results to stakeholders in a fast-paced environment, driving troubleshooting and process improvements with minimal