Scientist I - ADME Tox

Eurofins DiscoverX; Saint Charles (MO); On-site; USD 70,000 - 95,000; Full time

Benefits offered by this job

Medical, Dental, Vision

Life Insurance

401(k) with company match

Paid vacation and holidays

Job summary

Eurofins USA Discovery Services is seeking a Scientist I to join our ADME-Tox team. The role focuses on analytical chemistry method development and analysis within a CRO/industry lab setting, providing mentorship to junior scientists and leading daily lab operations.

Responsibilities include developing LC-MS methods for ADME/DMPK and BioAnalysis, supporting project teams, troubleshooting instruments, and contributing to method validation and data management. Commutable distance to St.

Qualifications

• 3+ years LC-MS experience in CRO or industry lab
• Bioanalytical method development for small/large molecules
• Mass spectrometry experience with high-throughput method development
• Experience with regulatory bioanalytical method validation (FDA, ICH, OECD)
• Experience in quality management systems
• Experience leading R&D/innovation programs
• Experience with cell culture in mammalian systems
• Experience using 384-well/96-well plate readers

Responsibilities

• Perform lab work and meet physical job requirements
• Provide mentorship and lab leadership
• Develop LC-MS methods for ADME/DMPK and BioAnalysis
• Support internal/external project teams with new assays
• Troubleshoot and maintain MS and HPLC instruments
• Prepare and manage buffers, reagents, and finished goods
• Contribute to process improvements and QC reviews
• Support validation of new methods and data management systems

Job description

Eurofins Scientific is an international life sciences company, providing a unique range of analytical testing services to clients across multiple industries, to make life and our environment safer, healthier and more sustainable. From the food you eat, to the water you drink, to the medicines you rely on, Eurofins laboratories work with the biggest companies in the world to ensure the products they supply are safe, their ingredients are authentic and labelling is accurate.

The Eurofins network of companies is the global leader in food, environment, pharmaceutical and cosmetic product testing and in agroscience Contract Research Organization services. It is one of the market leaders in certain testing and laboratory services for genomics, discovery pharmacology, forensics, advanced material sciences and in the support of clinical studies, as well as having an emerging global presence in Contract Development and Manufacturing Organizations. It also has a rapidly developing presence in highly specialized and molecular clinical diagnostic testing and in‑vitro diagnostic products.

In over 30 years, Eurofins has grown from one laboratory in Nantes, France to 58,000 staff across a decentralized and entrepreneurial network of 900 laboratories in over 54 countries. Eurofins companies offer a portfolio of over 200,000 analytical methods to evaluate the safety, identity, composition, authenticity, origin, traceability and purity of biological substances and products.

In 2024, Eurofins generated total revenues of EUR € 6,515 billion, and has been among the best performing stocks in Europe over the past 20 years.

Eurofins Scientific is an international life sciences company, providing a unique range of analytical testing services to clients across multiple industries, to make life and our environment safer, healthier and more sustainable. From the food you eat, to the water you drink, to the medicines you rely on, Eurofins laboratories work with the biggest companies in the world to ensure the products they supply are safe, their ingredients are authentic and labelling is accurate.

The Eurofins network of companies is the global leader in food, environment, pharmaceutical and cosmetic product testing and in agroscience Contract Research Organization services. It is one of the market leaders in certain testing and laboratory services for genomics, discovery pharmacology, forensics, advanced material sciences and in the support of clinical studies, as well as having an emerging global presence in Contract Development and Manufacturing Organizations. It also has a rapidly developing presence in highly specialized and molecular clinical diagnostic testing and in‑vitro diagnostic products.

In over 30 years, Eurofins has grown from one laboratory in Nantes, France to 58,000 staff across a decentralized and entrepreneurial network of 900 laboratories in over 54 countries. Eurofins companies offer a portfolio of over 200,000 analytical methods to evaluate the safety, identity, composition, authenticity, origin, traceability and purity of biological substances and products.

In 2024, Eurofins generated total revenues of EUR € 6,515 billion, and has been among the best performing stocks in Europe over the past 20 years.

Job Description

Are you looking to grow your experience in the ADME-Tox space? Look no further! Come join our dynamic and growing team for a great opportunity. The Scientist I will support the Eurofins Discovery business in contract research services. This role requires applied experience and proven knowledge in analytical chemistry method development and analysis, with related experience in a contract research organization (CRO) or industry laboratory.

Here's what you'll do:

• Perform work in a laboratory setting and meets the physical job requirements of a lab role.
• Provide leadership and mentorship for junior scientists, and lab leadership through daily lab management, equipment management and lab planning.
• Perform work in a laboratory setting, meeting the physical job requirements of a lab role.
• Develop Liquid Chromatography- Mass Spectrometry (LC-MS) methods for ADME/ DMPK and BioAnalysis applications
• Develop analytical methods supporting project teams both internally and externally for new assay development.
• Perform Troubleshooting and Maintenance of Mass Spectrometers and HPLC units.
• Experience with Sciex® or Thermo High Resolution/ Accurate Mass Instrumentation is a plus.
• Prepare and manages inventory of buffers, reagents, semi-finished and finished goods.
• Provide solutions to more complex problems, identifies and initiates process improvements
• Perform data and report QC review within the department and may support the Study Director.
• Support validation of new methods that contribute to expansion of service/product line, equipment, and data management systems.

Qualifications

The ideal candidate:

• 3+ years of of direct/demonstrated experience with Liquid Chromatography- Mass Spectrometry (LC-MS) in a contract research organization or industry laboratory in one or more of the following areas:
  • Bioanalytical Method Development for Small and/or Large Molecules
  • Drug Metabolism and Metabolite Identification w/ Structural Elucidation
  • Mass Spectrometry-Based Proteomics experimental design & execution
• Demonstrated experience with validation of bioanalytical methods in accordance with regulatory (FDA, ICH, OECD) guidelines.
• Experience working in a Quality Management System.
• Demonstrated proficiency in High-Throughput analytical method development for small molecules.
• Experience in leading and delivering results in R&D or innovation programs.
• Demonstrated experience leading in human mammalian cell culture laboratories.
• Demonstrated experience working with light-based readers with 384-well and 96-well plates.
• B.S. with 3 years of relevant experience
• M.S. with 2 years of relevant experience
• Ph.D. with 1 years of relevant experience
• Or an equivalent combination of education and experience

Additional Information

The position is full-time, Monday-Friday, 8 a.m.- 5 p.m., with overtime as needed. Candidates living within a commutable distance of St. Charles, MO are encouraged to apply.

• Excellent full time benefits including comprehensive medical coverage, dental, and vision options
• Life and disability insurance
• 401(k) with company match
• Paid vacation and holidays

Eurofins USA Discovery Services is a Disabled and Veteran Equal Employment Opportunity employer.