LCMS Scientist

Eurofins DiscoverX; Saint Charles (MO); On-site; USD 85,000 - 120,000; Full time

Benefits offered by this job

Medical, dental, vision benefits

Life and disability insurance

401(k) with company match

Paid vacation and holidays

Job summary

Eurofins USA Discovery Services seeks a Scientist I – Analytical Chemist to support analytical chemistry methods in a CRO setting. The role emphasizes LC-MS method development for ADME/DMPK, data quality, and collaboration with internal and external project teams.

The candidate will contribute to method validation, training, and expansion of service lines while ensuring compliance with GxP and regulatory guidelines at a US laboratory in Saint Charles, MO.

Qualifications

• Direct experience with LC-MS and/or LC-UV in CRO or industry lab.
• Experience working in a Quality Management System.
• Scientific expertise with mass spectrometry-based quantification in biological matrices.
• Experience with analytical method development and optimization.
• Familiarity with FDA/ICH method validation guidelines.
• Experience with liquid handling, automation, SPE, HTS and screening.
• Experience in leading small teams and project management.
• Ability to work with minimal supervision on R&D programs.

Responsibilities

• Develops LC-MS methods for ADME/DMPK applications.
• Supports project teams with new assay development.
• Maintains QC of data and reports; supports study directors.
• Provides training to colleagues and end users as needed.
• Ensures work complies with GxP site requirements.

Skills

LC-MS experience

Mass spectrometry-based quantification

Analytical method development

Validation concepts (FDA/ICH)

SPE / liquid handling / automation

Leadership & project management

Data QC / reporting

Education

B.S. degree with 5+ years laboratory experience

M.S. degree with 3+ years laboratory experience

Ph.D. with 1+ year laboratory experience

Equivalent combination of education and experience

Tools

Sciex instrumentation

Waters instrumentation

HPLC

Job description

Eurofins Scientific is an international life sciences company, providing a unique range of analytical testing services to clients across multiple industries, to make life and our environment safer, healthier and more sustainable. From the food you eat, to the water you drink, to the medicines you rely on, Eurofins laboratories work with the biggest companies in the world to ensure the products they supply are safe, their ingredients are authentic and labelling is accurate.

The Eurofins network of companies is the global leader in food, environment, pharmaceutical and cosmetic product testing and in agroscience Contract Research Organization services. It is one of the market leaders in certain testing and laboratory services for genomics, discovery pharmacology, forensics, advanced material sciences and in the support of clinical studies, as well as having an emerging global presence in Contract Development and Manufacturing Organizations. It also has a rapidly developing presence in highly specialized and molecular clinical diagnostic testing and in-vitro diagnostic products.

In over 30 years, Eurofins has grown from one laboratory in Nantes, France to 58,000 staff across a decentralized and entrepreneurial network of 900 laboratories in over 54 countries. Eurofins companies offer a portfolio of over 200,000 analytical methods to evaluate the safety, identity, composition, authenticity, origin, traceability and purity of biological substances and products.

In 2024, Eurofins generated total revenues of EUR € 6,515 billion, and has been among the best performing stocks in Europe over the past 20 years.

Eurofins Scientific is an international life sciences company, providing a unique range of analytical testing services to clients across multiple industries, to make life and our environment safer, healthier and more sustainable. From the food you eat, to the water you drink, to the medicines you rely on, Eurofins laboratories work with the biggest companies in the world to ensure the products they supply are safe, their ingredients are authentic and labelling is accurate.

The Eurofins network of companies is the global leader in food, environment, pharmaceutical and cosmetic product testing and in agroscience Contract Research Organization services. It is one of the market leaders in certain testing and laboratory services for genomics, discovery pharmacology, forensics, advanced material sciences and in the support of clinical studies, as well as having an emerging global presence in Contract Development and Manufacturing Organizations. It also has a rapidly developing presence in highly specialized and molecular clinical diagnostic testing and in-vitro diagnostic products.

In over 30 years, Eurofins has grown from one laboratory in Nantes, France to 58,000 staff across a decentralized and entrepreneurial network of 900 laboratories in over 54 countries. Eurofins companies offer a portfolio of over 200,000 analytical methods to evaluate the safety, identity, composition, authenticity, origin, traceability and purity of biological substances and products.

In 2024, Eurofins generated total revenues of EUR € 6,515 billion, and has been among the best performing stocks in Europe over the past 20 years.

Job Description

The Scientist I – Analytical Chemist will support the Eurofins Discovery business in contract research services. This role requires applied experience and proven knowledge in analytical chemistry methods with related experience in a contract research organization (CRO) or industry laboratory.

LCMS Scientist Responsibilities & Duties Include but are not Limited to the Following:

• Performs work in a laboratory setting, meeting the physical job requirements of a lab role.
• Conducts production assays primarily in ADME Toxicology Services, but may support BioMAP®, Immunosignaling, Ion Channel, and/or OncoPanel™ Services based on business needs.
• Develops Liquid Chromatography- Mass Spectrometry (LC-MS) methods for ADME/ DMPK applications
• Develops analytical methods supporting project teams both internally and externally for new assay development.
• Performs Troubleshooting and Maintenance of Mass Spectrometers and HPLC units. Experience with Sciex® or Waters Instrumentation is a plus.
• Prepares and manages inventory of buffers, reagents, semi-finished and finished goods.
• Provides solutions to more complex problems, identifies and initiates process improvements
• Maintains high data quality and reproducibility.
• Performs data and report QC review within the department, and may support study director.
• Takes ownership of client projects with minimal supervision.
• Supports validation of new methods, and contributes to expansion of service/product line, equipment, and data management systems.
• Understands and complies with requirements for work performed at a GxP site.
• Completes required training and supports 100% of Employee Health and Safety requirements.
• Demonstrates proficiency with, care and maintenance of lab equipment and department assets.
• Conducts responsible use of confidential IT and business systems, as required.
• Adheres to department SOPs and documentation requirements, maintains accurate data management and reporting.
• Supports unit goals and demonstrates Eurofins' competencies, as defined in the job plan.
• Provides training to colleagues and external end users, when required.
• Contributes to scientific community, and site research and development objectives.
• Works effectively in a team environment, under minimum direction, to achieve business production, project timelines, and quality objectives.
• Adjusts work hours and provides cross-functional support to other departments, as required, and maintains accountability in delivering to client needs/timelines.
• Routinely communicates project updates to internal and external clients.
• Performs other duties, as assigned/

Qualifications

Basic Minimum Education Requirements

• B.S. with minimum 5 years relevant laboratory experience
• M.S. with minimum 3 years relevant laboratory experience
• Ph.D. with minimum 1 year relevant laboratory experience
• Or an equivalent of education and laboratory experience

Basic Minimum Work Requirements

• Direct experience with Liquid Chromatography- Mass Spectrometry and/or ultraviolet spectrometry (LC-MS or LC-UV) in a contract research organization or industry laboratory for ADME/ DMPK applications
• Experience working in a Quality Management System
• Scientific expertise with mass spectrometry-based quantification for ADME/ DMPK applications in biological matrices.
• Experience with analytical method development and optimization
• Familiarity with concepts of validation of bioanalytical methods in accordance with regulatory (FDA, ICH) guidelines
• Experience with liquid handling, automation, solid-phase extraction (SPE), HTS applications, and large-scale screening
• Experience in small team leadership and project management
• Experience in leading and delivering results in R&D or innovation programs
• Authorization to work in the United States indefinitely without restriction or sponsorship.

The Ideal Candidate Possesses the Following:

• Good communication and interpersonal skills
• Demonstrated proficiency in contributing independently on a project team with time and quality deliverables
• Ability to read, write, and interpret documents, such as standard operating procedures and technical reports
• Ability to perform mathematical calculations, statistical analyses, and data interpretation
• Ability to multitask with organization and manage time effectively
• Ability to solve practical problems and troubleshooting skills
• Ability to work in a laboratory setting, according to physical requirements of a laboratory role
• Lab equipment and office computer/software proficiency
• Above average oral and written communication skills
• Demonstrates a positive attitude, capacity for team environment, and exhibits a genuine interest in drug discovery in support of advancing human health
• Ability to develop new methods, and lead research and development projects
• Ability to review and QC release data/reports
• Ability to lead small, informal sub-teams, train, and train new team members
• Ability to conduct mid-size projects with minimal supervision
• Ability to contribute to strategic vision, establishment of new service lines, equipment, and data management systems
• Ability to easily support cross-functional demands

Additional Information

Position is full-time working Sunday - Thursday or Saturday - Wednesday 8:00pm - 5:00 PM. Candidates currently living within a commutable distance of St. Charles, MO are encouraged to apply.

• Excellent full-time benefits including comprehensive medical coverage, dental, and vision options
• Life and disability insurance
• 401(k) with company match
• Paid vacation and holidays

Eurofins USA Discovery Services is a Disabled and Veteran Equal Employment Opportunity employer.