Scientist I - ADME Tox

Eurofins; Saint Charles (MO); On-site; USD 70,000 - 95,000; Full time

Benefits offered by this job

Medical, dental, and vision coverage

Life and disability insurance

401(k) with company match

Paid vacation and holidays

Job summary

Eurofins USA Discovery Services in Saint Charles, MO seeks a Scientist I to join its growing ADME-Tox team. You will apply analytical chemistry expertise to develop LC-MS methods and support contract research in a fast-paced lab environment.

The ideal candidate has hands-on LC-MS experience, method development and validation under regulatory guidelines, and the ability to mentor junior scientists while contributing to project teams and process improvements.

Qualifications

• 3+ years of LC-MS experience in CRO or industry lab.
• Experience with method development and validation per FDA/ICH/OECD.
• Experience in Quality Management Systems.
• Experience with high-throughput analytical method development for small molecules.
• Experience leading R&D or innovation programs.

Responsibilities

• Develop LC-MS methods for ADME/DMPK and BioAnalysis applications.
• Lead and mentor junior scientists and manage lab planning.
• Troubleshoot and maintain Mass Spectrometers and HPLC units.
• Prepare and manage buffers, reagents, and inventory.
• Support validation of new methods and data management systems.
• Perform data QC review and assist the Study Director.

Skills

Leadership & mentoring

Laboratory management

Analytical thinking

Education

Bachelor's degree in Chemistry or related field

Master's degree in a relevant field

Ph.D. in a relevant field

Tools

LC-MS instrumentation

HPLC

Sciex/Thermo instruments familiarity

Job description

Company Description

Eurofins Scientific is an international life sciences company, providing a unique range of analytical testing services to clients across multiple industries, to make life and our environment safer, healthier and more sustainable. From the food you eat, to the water you drink, to the medicines you rely on, Eurofins laboratories work with the biggest companies in the world to ensure the products they supply are safe, their ingredients are authentic and labelling is accurate.

The Eurofins network of companies is the global leader in food, environment, pharmaceutical and cosmetic product testing and in agroscience Contract Research Organization services. It is one of the market leaders in certain testing and laboratory services for genomics, discovery pharmacology, forensics, advanced material sciences and in the support of clinical studies, as well as having an emerging global presence in Contract Development and Manufacturing Organizations. It also has a rapidly developing presence in highly specialized and molecular clinical diagnostic testing and in-vitro diagnostic products.

In over 30 years, Eurofins has grown from one laboratory in Nantes, France to 58,000 staff across a decentralized and entrepreneurial network of 900 laboratories in over 54 countries. Eurofins companies offer a portfolio of over 200,000 analytical methods to evaluate the safety, identity, composition, authenticity, origin, traceability and purity of biological substances and products.

In 2024, Eurofins generated total revenues of EUR € 6,515 billion, and has been among the best performing stocks in Europe over the past 20 years.

Job Description

Are you looking to grow your experience in the ADME-Tox space? Look no further! Come join our dynamic and growing team for a great opportunity. The Scientist I will support the Eurofins Discovery business in contract research services. This role requires applied experience and proven knowledge in analytical chemistry method development and analysis, with related experience in a contract research organization (CRO) or industry laboratory.

Here’s What You’ll Do

• Perform work in a laboratory setting and meets the physical job requirements of a lab role.
• Provide leadership and mentorship for junior scientists, and lab leadership through daily lab management, equipment management and lab planning.
• Perform work in a laboratory setting, meeting the physical job requirements of a lab role.
• Develop Liquid Chromatography- Mass Spectrometry (LC-MS) methods for ADME/ DMPK and BioAnalysis applications
• Develop analytical methods supporting project teams both internally and externally for new assay development.
• Perform Troubleshooting and Maintenance of Mass Spectrometers and HPLC units.
• Experience with Sciex® or Thermo High Resolution/ Accurate Mass Instrumentation is a plus.
• Prepare and manages inventory of buffers, reagents, semi-finished and finished goods.
• Provide solutions to more complex problems, identifies and initiates process improvements
• Perform data and report QC review within the department and may support the Study Director.
• Support validation of new methods that contribute to expansion of service/product line, equipment, and data management systems.

Qualifications

The ideal candidate:

• 3+ years of of direct/demonstrated experience with Liquid Chromatography- Mass Spectrometry (LC-MS) in a contract research organization or industry laboratory in one or more of the following areas:
• Bioanalytical Method Development for Small and/or Large Molecules
• Drug Metabolism and Metabolite Identification w/ Structural ElucidationMass Spectrometry-Based Proteomics experimental design & execution
• Demonstrated experience with validation of bioanalytical methods in accordance with regulatory (FDA, ICH, OECD) guidelines.
• Experience working in a Quality Management System.
• Demonstrated proficiency in High-Throughput analytical method development for small molecules.
• Experience in leading and delivering results in R&D or innovation programs.
• Demonstrated experience leading in human mammalian cell culture laboratories.
• Demonstrated experience working with light-based readers with 384-well and 96-well plates.
• B.S. with 3 years of relevant experience
• M.S. with 2 years of relevant experience
• Ph.D. with 1 years of relevant experience
• Or an equivalent combination of education and experience
• Ability to work in the U.S. indefinitely without sponsorship or restriction

Additional Information

The position is full-time, Monday-Friday, 8 a.m.- 5 p.m., with overtime as needed. Candidates living within a commutable distance of St. Charles, MO are encouraged to apply.

• Excellent full time benefits including comprehensive medical coverage, dental, and vision options
• Life and disability insurance
• 401(k) with company match
• Paid vacation and holidays

Eurofins USA Discovery Services is a Disabled and Veteran Equal Employment Opportunity employer.