Scientist 3: Lung Immunology & Inflammation

Genentech; San Francisco (CA); Hybride; USD 103 000 - 192 000; Plein temps

Résumé du poste

Genentech’s Immunology Department seeks a Scientist with deep expertise in lung biology and immunology to identify novel therapeutic targets for respiratory diseases. You will lead projects on injury, inflammation, and repair, and push research programs toward early clinical development using state-of-the-art models and analyses.

The role requires a PhD with strong publications, hands-on molecular biology skills, experience with primary cells and flow cytometry, and a track record of

Qualifications

• PhD in immunology, stem cell biology, molecular biology, biochemistry, or a related field with a track record of high-quality publications.
• Deep understanding of lung biology, chronic respiratory diseases, tissue remodeling/regeneration, or host-microbe interactions.
• Hands-on molecular biology including transfections, gene expression profiling, precision genome editing, and targeted RNA delivery.
• Experience with primary cell isolation from human or mouse tissues, in vitro immunological assays, and multi-dimensional flow cytometry.
• Independent design, execution, troubleshooting, and interpretation of complex experiments leading to first-author publications.

Responsabilités

• Lead projects investigating cellular and molecular mechanisms of lung injury, inflammation, and repair.
• Advance research into early clinical development by generating robust proof-of-concept data.
• Utilize in vitro and in vivo models to evaluate novel molecules and delivery systems.
• Dissect pathogenesis of inflammatory lung diseases and determine MOA of therapies.
• Foster collaborations across immunology, human genetics, biomarker discovery, and early clinical development.
• Present findings at internal and cross-departmental meetings.

Description du poste

Genentech’s Immunology Department seeks a Scientist with deep expertise in lung biology and immunology to identify novel therapeutic targets for respiratory diseases. You will lead projects on injury, inflammation, and repair, and push research programs toward early clinical development using state-of-the-art models and analyses.

The role requires a PhD with strong publications, hands-on molecular biology skills, experience with primary cells and flow cytometry, and a track record of