Scientist

Nabsys; Providence (RI); On-site; USD 110,000 - 160,000; Full time

Benefits offered by this job

Health, dental, vision

401(k) plan with 50% match up to 6%

Unlimited vacation

Life insurance

Equity stake

Job summary

Nabsys in Providence, RI seeks an Analytical Development Scientist/Senior Scientist, Consumables to lead HPLC-based method development and QC for sample prep components, supporting consumables manufacture as demand grows. You will build measurement infrastructure and author SOPs for quality control of biotech consumables.

You will collaborate across engineering and biology teams to advance sample prep chemistry, data analysis, and quality system development in a fast-paced startup environment.

Qualifications

• PhD in analytical chemistry, biochemistry, molecular biology, or related field.
• 2+ years analytical development, process development, or similar lab experience in biotech or pharma.
• Hands-on HPLC experience including method development.
• Experience with a range of analytical techniques and data analysis.
• Background in genomics, nucleic acid chemistry, or molecular biology preferred.
• Proficiency in UV-Vis, SDS-PAGE, gel electrophoresis, and PCR.
• Excellent organizational and communication skills.

Responsibilities

• Build and implement the QC framework for sample prep components.
• Develop, optimize, and validate HPLC methods for analysis.
• Lead preparative-scale production of sample prep components (AKTA/FPLC).
• Execute production of additional sample prep consumables.
• Perform incoming raw material QC and finished-goods checks.
• Execute timepoints for shelf-life studies and data reporting.
• Author SOPs, qualification protocols, and analytical reports.
• Collaborate with engineers and scientists to advance chemistry and quality systems.
• Communicate findings and recommendations to cross-functional teams.

Skills

Analytical chemistry

Molecular biology

Laboratory techniques

Scientific communication

Education

PhD in analytical chemistry, biochemistry, molecular biology, or related field

Tools

FPLC/ÄKTA systems

HPLC

LC-MS

NMR

GC

FTIR

Job description

Nabsys is advancing genomics with a clear focus on accessibility and innovation through its proprietary electronic genome mapping (EGM) technology. Implemented on the OhmX Platform™, EGM integrates precision electronics, nanofluidics, and computational biology to deliver high-resolution insight into genome structure. This approach expands what’s possible in cytogenetics, molecular genetics, and cell and gene therapy research, while providing comprehensive structural variation analysis to laboratories of all sizes. The company was founded in 2005 and is based in Providence, Rhode Island. For more information, visit www.nabsys.com.

Title

Analytical Development Scientist/Senior Scientist, Consumables

Position Overview

We are seeking a motivated Scientist to join the Technology Development group as part of the Consumables team. In this role, you will be a leader in the process and analytical method development — with a primary focus on HPLC-based techniques — that underpin quality control of sample preparation consumables. You will work both independently and collaboratively on fast-paced projects, leveraging your expertise in analytical chemistry and molecular biology to build measurement infrastructure and support production processes as consumables manufacturing scales to meet commercial demand. Position level is commensurate with experience.

Responsibilities

• Build and implement the QC framework for sample prep components following typical analytical method validation principals, covering a wide range of molecular biology and analytical chemistry techniques and instrumentation
• Develop, optimize, and validate HPLC methods for sample prep component and raw material analysis, including nucleotide identity and purity and small-molecule quantification
• Lead preparative-scale production of sample prep components, including scale-up process development using AKTA/FPLC, with increasing ownership as processes are developed and documented
• Execute production of additional sample prep consumables under established protocols
• Perform incoming raw material QC and finished-goods analytical checks in support of consumables release decisions
• Execute analytical timepoints for the sample prep component shelf life studies, including sample management and data reporting
• Author method SOPs, qualification protocols, and analytical reports to internal documentation standards
• Participate in cross-functional projects with engineers and other scientists to advance sample preparation chemistry and quality system development goals
• Effectively communicate findings, data analysis, and recommendations to cross-functional teams and stakeholders

Requirements

• PhD in analytical chemistry, biochemistry, molecular biology, or related field required; >2+ years analytical development, process development, or similar lab experience in biotech or pharma is required
• Experience with FPLC/ÄKTA systems for preparative-scale nucleic acid or protein purification
• Demonstrated hands-on HPLC experience including method development; experience with nucleotide, nucleoside, or small-molecule analyte analysis is strongly preferred
• Clear background in development and implementation of a wide range of analytical techniques; experience with LC-MS, NMR, GC, FTIR, etc. instrumentation, sample prep, and data analysis is preferred
• Prior experience in genomics, nucleic acid chemistry, or molecular biology is preferred
• Proficiency in standard molecular biology techniques including but not limited to UV-Vis spectrophotometry, SDS-PAGE, gel electrophoresis, and PCR
• Excellent organizational and time management skills, with the ability to multitask in a fast paced startup environment
• Excellent written and verbal communication skills are required

Compensation

• Competitive salary and bonus structure
• Equity stake
• Benefits include health, dental, vision, 401(k) plan with 50% match up to 6% of base salary, unlimited vacation, life insurance