Research Associate

Bruker; Boston (MA); On-site; USD 63,000 - 100,000; Full time

Benefits offered by this job

401(k) with company match

Employee stock purchase plan

Medical and dental plans

Life insurance

Disability insurance (short/long-term)

Paid time off (vacation, sick time, &H

Job summary

Biognosys, an entity of Bruker Scientific, established a Newton, MA laboratory to offer proteomics and metabolomics services. We seek a motivated Research Associate to support sample preparation and LC-MS/MS data acquisition, ensuring compliance with our quality standards.

You will work within a collaborative team of scientists, handling customer samples, performing LC-MS analyses, and contributing to method development and documentation.

Qualifications

• 1–3 years experience in proteomic and metabolic / lipidomic sample preparation.
• 1–3 years laboratory experience handling biological samples (cell lysates or patient samples).
• Experience with LC-MS instrumentation and DIA/PRM/MRM methods is advantageous (Q-TOF, triple Quad, Orbitrap).
• Experience in a GCLP regulated environment is advantageous.
• Strong documentation skills and computer proficiency.

Responsibilities

• Overview of customer samples throughout their life cycle: receipt, storage, tracking, preparation, LC-MS data acquisition and QC.
• Maintenance and troubleshooting of LC-MS instrumentation (timsTOF, EVOQ, Evosep, Elute).
• Management and upkeep of laboratory equipment to ensure peak performance.
• Documentation of all activities in lab notebooks and ELNs.
• Contribution to SOP improvements and customer reports/mapers.

Skills

Proteomics experience

Laboratory experience

Documentation skills

MS Office skills

Education

BSc or MSc in analytical/biochemistry/biotechnology

Tools

LC-MS systems

DIA/PRM/MRM methods

Q-TOF/Orbitrap

GCLP environment experience

Job description

Job Locations

US-MA-Boston Area

Overview

As one of the world's leading analytical instrumentation companies, Bruker covers a broad spectrum of advanced solutions in all fields of research and development. All our systems and instruments are designed to improve safety of products, accelerate time-to-market and support industries in successfully enhancing quality of life. We've been driving innovation in analytical instrumentation for 60 years now. Today, worldwide more than 11,000 employees are working on this permanent challenge, at over 90 locations on all continents.

At Biognosys (an entity of Bruker Scientific), we believe that deep proteome insights hold the key to breakthrough discoveries that transform science for better lives. With our versatile portfolio of next-generation proteomics solutions, including the TrueDiscovery, TrueTarget, and TrueSignature research service platforms, our flagship software Spectronaut, and the PQ500 kit, we make the proteome actionable to empower research, drug development, and clinical decision-making. Our solutions provide a multi-dimensional view of protein expression, function, and structure in all biological species and sample types. Our unique, patented technologies utilize high-resolution mass spectrometry to quantify thousands of proteins with industry-leading precision, depth, and throughput. Through a recent partnership with Biocrates, we are extending the services metabolomics and lipidomics.

THE OPPORTUNITY

Biognosys (an entity of Bruker Scientific) established a laboratory in Newton, MA to offer next-generation proteomics services and targeted metabolomics and lipidomics to the local and global community. These services enable the unbiased exploration of the proteome across a variety of samples types and applications, from early drug discovery to clinical trials.

We are looking for a motivated Research Associate to join our operations team in Newton. This is a laboratory-based position, in which the candidate will focus on customer sample preparation and HPLC-MS/MS data acquisition. The candidate will perform activities in compliance with Biognosys' quality standards. Together with a strong team of dedicated scientists, you will make Biognosys' next generation proteomics and metabolomics / lipidomics technologies available and actionable for the pharma and biotechnology industry and be a key driver of success at our site in Newton, Massachusetts.

Responsibilities

• Overview of customer samples throughout their life cycle: sample receipt, storage and tracking, manual and semi-automated sample preparation, liquid chromatography mass spectrometry (LC-MS) data acquisition, and quality control of generated data following Biognosys' standard operating procedures (SOP)
• Maintenance and troubleshooting of LC-MS instrumentation (timsTOF, EVOQ, Evosep, Elute)
• Management, maintenance and evaluation of laboratory equipment, ensuring their operation at the highest level
• Documentation of all performed activities in lab notebooks and ELNs
• Contribution to improvement of sample preparation methods and SOP, customer report and method writing
• General laboratory tasks (ordering of consumables, preparation of buffers, etc)

Qualifications

• BSc or MSc degree in relevant scientific field preferably analytical direction (pharmacy, analytical or biochemistry, molecular biology, biotechnology)
• 1-3 years experience in proteomic and metabolic / lipidomic sample preparation
• 1-3 years laboratory experience handling biological samples such as cell lysates or patient samples, either from academia, healthcare or biotech/pharma
• Previous experience in working with chromatographic (LC) systems or mass spectrometers using DIA, PRM and MRM methods is an advantage (Q-TOF, triple Quad, Orbitrap)
• Previous experience of working in a GCLP regulated environment is an advantage
• Solid computer skills including MS Office
• Well organized, independent and reliable, while still being a team player
• Excellent documentation skills and understanding the importance of timely chronicling

At Bruker, the base salary is part of our total compensation. The estimated base salary range for this full-time position is between $62,500.00 and $100,000.00 and provides an opportunity to progress as you grow and develop within a role. The base salary for the role will depend on several job-related factors, including, but not limited to, education, training, experience, the geographic location of the successful candidate, skills, competencies, job-related knowledge, and travel requirements for this position. Full-time employees may also be eligible for a performance-related incentive in addition to a full range of benefits, including 401(k) with company match, an employee stock purchase plan, medical and dental plans, life insurance, short-term and long-term disability insurance, employee assistance program and paid time off including vacation, sick time and holidays, and more.

• performance-related incentive
• 401(k) with company match
• employee stock purchase plan
• medical and dental plans
• life insurance
• short-term disability insurance
• long-term disability insurance
• employee assistance program
• paid time off including vacation, sick time and holidays

Bruker is an equal opportunity employer. We evaluate qualified applicants without regard to race, color, religion, sex, national origin, disability, veteran status, and other protected characteristics.

Certain positions at Bruker require compliance with export control laws and as a result, all interviewed candidates for all positions will be screened pre-interview to determine their eligibility in light of export control restrictions.