Rheumatology Preclinical Scientist II

BioSpace; Cambridge (MA); On-site; USD 120,000 - 180,000; Full time

Benefits offered by this job

Paid time off

Medical/dental/vision insurance

401(k)

Job summary

AbbVie in Cambridge, MA seeks a Senior Scientist II to advance preclinical rheumatology programs. You will lead target validation, mechanism studies, and translational efforts to bridge human disease biology with preclinical data. Strong in vivo expertise and collaboration across teams are essential for success.

The role emphasizes in vivo KD/PD work, data integration, and generation of high-quality data packages to guide program strategy.

Qualifications

• Bachelor's degree with 12+ years of experience.
• Master's degree with 10+ years of experience.
• PhD with 4+ years of experience.

Responsibilities

• Set Rheumatology strategy for pipeline programs and contribute to target evaluation.
• Drive in vitro and in vivo pharmacology, establish PK/PD relationships, and optimize assays.
• Develop murine models of inflammation to support preclinical development.
• Apply flow cytometry, gene expression analysis, protein and cytokine quantification, histopathology.
• Design experiments, analyze data, and present findings at AbbVie scientific forums.
• Author and review technical reports, protocols, and other key documents.
• Adhere to corporate standards for safety and humane animal care.

Skills

Immunology

In vivo pharmacology

Data analysis

Flow cytometry

Scientific communication

Education

Bachelor's degree

Master's degree

PhD

Job description

AbbVie in Cambridge, MA seeks a Senior Scientist II to advance preclinical rheumatology programs. You will lead target validation, mechanism studies, and translational efforts to bridge human disease biology with preclinical data. Strong in vivo expertise and collaboration across teams are essential for success.

The role emphasizes in vivo KD/PD work, data integration, and generation of high-quality data packages to guide program strategy.