Senior Scientist II – Rheumatology Translational Immunology

AbbVie; Cambridge (MA); On-site; USD 140,000 - 190,000; Full time

Benefits offered by this job

Paid time off

Health insurance

401(k) plan

Long-term incentives

Job summary

AbbVie's Discovery Immunology R&D team at the Cambridge Research Center is seeking a Senior Scientist II to advance preclinical programs in rheumatology with a focus on RA and PsA. The role emphasizes mechanism-of-action studies, translational research, and in vivo model development.

The ideal candidate will bring deep immunology expertise, strong preclinical pharmacology experience, and a track record of leading scientific initiatives within cross-functional teams.

Qualifications

• Proven expertise in in vitro and preclinical in vivo model systems.
• Excellent interpersonal, communication, and collaboration skills.
• Ability to work effectively in cross-functional teams across locations.

Responsibilities

• Set Rheumatology strategy for pipeline programs and contribute to target evaluation and model development.
• Drive in vitro and in vivo pharmacology for drug candidates, including PK/PD relationships and assay development.
• Develop acute and chronic murine inflammation models to support preclinical development.
• Apply immunological techniques such as flow cytometry, gene expression analysis, protein quantification and histopathology.
• Design experiments, analyze data, and present findings at AbbVie forums and external conferences.
• Author and review technical reports and protocols.

Skills

Immunology

In vivo pharmacology

Preclinical pharmacology

Cross-functional teamwork

Education

Bachelor’s Degree with 12 years experience

Master’s Degree with 10 years experience

PhD with 4 years experience

Job description

AbbVie's Discovery Immunology R&D team at the Cambridge Research Center is seeking a Senior Scientist II to advance preclinical programs in rheumatology with a focus on RA and PsA. The role emphasizes mechanism-of-action studies, translational research, and in vivo model development.

The ideal candidate will bring deep immunology expertise, strong preclinical pharmacology experience, and a track record of leading scientific initiatives within cross-functional teams.