Researcher 2- Neurology

The Ohio State University Wexner Medical Center; Columbus (OH); On-site; USD 65,000 - 90,000; Full time

Job summary

The Ohio State University Wexner Medical Center invites applications for a Researcher 2 in the Pelotonia Institute for Immuno-Oncology (PIIO). The role supports Dr. Acharya's lab to study neuro-immune interactions in cancer and develop novel immunotherapeutic strategies.

Responsibilities include executing advanced techniques (flow cytometry, CRISPR-Cas9, scRNA-seq), data analysis, and preparing reports and grant submissions, with opportunities to train staff and conduct animal procedures.

Qualifications

• Master's degree or equivalent experience; 3 years relevant experience with Bachelor's, or 1 year with Master's.
• Strong background in molecular immunology and cancer biology.
• Experience with lab animal procedures.

Responsibilities

• Execute research projects using flow cytometry, CRISPR-Cas9, scRNA-seq, and bulk RNA-seq.
• Collaborate with PI to analyze data, prepare reports, manuscripts, and grant submissions.
• Train research staff in basic and advanced lab techniques and perform routine animal procedures.

Skills

Flow cytometry

CRISPR-Cas9

RNA sequencing

Immunohistochemistry

Tissue culture

Genotyping

qPCR

Education

Master's degree or equivalent

PhD in Biochemistry or related field

Tools

Bioluminescent imaging

Xenograft implantation

Stereotactic techniques

Genotyping

Job description

Current Employees and Students: Please log in to Workday to use the internal job search and application process.

Scope/Summary

A Researcher 2 position is available in the laboratory of Dr. Acharya, in the Ohio State University Comprehensive Cancer Center (OSUCCC) Pelotonia Institute for Immuno-Oncology (PIIO). The laboratory of Dr. Acharya studies how cellular and molecular determinants in the neuro-immune axis influence cancer initiation, progression, and metastasis. She is also researching the role of neuro-immune crosstalk and how this process shapes anti-tumor immune responses. This work will significantly increase our understanding of how tumors develop and grow, help to identify new biomarkers for cancer diagnosis, and define novel targets for therapeutic interventions.

The Researcher 2 will be integrated into a highly collaborative and dynamic immuno-oncology research environment at the Pelotonia Institute for Immuno-Oncology (PIIO), with access to state-of-the-art facilities and technologies. The Researcher 2 will execute research projects using techniques such as high-dimensional multiparameter flow cytometry, CRISPR-Cas9, single-cell RNA sequencing (scRNA-seq) and bulk RNA sequencing (RNA-seq), multispectral imaging, immunohistochemistry, Western blotting, tissue culture, genotyping, and qPCR. Under the guidance of Dr. Acharya, the Researcher 2 will conduct specialized research aimed at identifying novel therapeutics that can synergize with existing immunotherapy modalities. The Researcher 2 will collaborate with the principal investigator in analyzing and interpreting research data, compiling results, and preparing reports, manuscripts, and grant submissions. The Researcher 2 will also participate in training research staff in both basic and advanced laboratory techniques and perform routine laboratory animal procedures.

Minimum Qualifications

• Master's Degree or equivalent experience required; 3 years of relevant experience required with Bachelor's Degree, or 1 year of relevant experience required with Master's Degree.

Preferred Qualifications

• A Ph.D. in Biochemistry or other relevant field is required.
• Extensive experience with mouse models is desirable, including preparation of pre-operative brain tumor cell suspensions, stereotactic orthotopic xenograft implantation of brain tumors in mice, and use of bioluminescent imaging to monitor tumor growth and response to therapy.
• Strong publication record is desired.
• Ability to write up project findings and draft proposals and manuscripts for publication is desired.
• The university requires completion of a background check and qualified candidates may be asked to complete a pre-employment physical including a drug screen.

Career Roadmap

FUNCTION: Research and Scholarship

SUB-FUNCTION: Research

CAREER BAND: Individual Contributor - Specialized

CAREER LEVEL: S2

The OSUCCC – James is the only cancer program in the United States that features a National Cancer Institute (NCI)-designated comprehensive cancer center aligned with a nationally ranked academic medical center and a freestanding cancer hospital on the campus of one of the nation’s largest public universities. The Pelotonia Institute for Immuno-Oncology (PIIO) is a comprehensive bench-to-bedside research initiative focused on harnessing the body’s immune system to fight cancer at all levels —from prevention to treatment and survivorship. The Laboratory of Dr. Acharya is a part of the OSUCCC-James, PIIO. Dr. Acharya’s research focuses on comprehensive understanding of the tumor microenvironment that will aid the development of holistic therapeutic strategies for the treatment of cancer.

Thank you for your interest in working at Ohio State.

The university is an equal opportunity employer, including veterans and disability.

Final candidates are subject to successful completion of a background check. A drug screen or physical may be required during the post offer process.