Researcher 1- Neurological Surgery

The Ohio State University Wexner Medical Center; Columbus (OH); On-site; USD 45,000 - 65,000; Full time

Job summary

The Ohio State University Wexner Medical Center is seeking a Research Associate to participate in planning, design, execution, and management of in‑vivo studies in a translational pre‑clinical program focused on CNS disorders. The role requires expertise in necropsy, tissue processing, histology, and data management to support FDA submissions.

The candidate will work closely with laboratory veterinarians and IACUC staff to ensure GLP standards, prepare research papers, and contribute to grant

Qualifications

• Experience with in vivo animal research is preferred.
• Knowledge of IACUC, GLP, and regulatory requirements is desirable.
• Strong data collection and record-keeping skills.

Responsibilities

• Plan, design, execute and manage in-vivo research studies in CNS translational preclinical projects.
• Lead necropsy activities in small and large animals and ensure quality sample handling.
• Perform histology tasks including tissue processing, embedding, and staining.
• Collect, analyze and interpret data; maintain records for FDA submissions.
• Collaborate with veterinarians and staff to update IACUC protocols as needed.

Skills

In vivo animal work

Neuroscience research

Data analysis

Education

Bachelor’s degree in a life science or related field

Tools

Necropsy equipment

Histology equipment

Job description

Research Associate who participates in planning, design, execution, and management of all in‑vivo research studies and activities in a research laboratory investigating translational pre‑clinical studies in the development of AAV, drug‑loaded liposomes, mRNA‑based nanoparticles‑based gene therapies for central nervous system disorders such as Parkinson’s disease, Huntington’s disease, AADC deficiency, Alzheimer’s disease, lysosomal storage disorders, hearing loss, and depression in the Department of Neurological Surgery; participates in the execution of ongoing research projects; proficient in specialized necropsy techniques in small and large animals with the ability to lead necropsy function in the lab; leads efficient and high‑quality sample collection, processing, tissue preservation and tissue trimming according to study protocols; assists with histology duties such as tissue processing, embedding, frozen sections, sorting, cutting, filing, reagent preparation, special stains, and staining slides of tissue samples; collects, analyzes, and interprets research data; assists in establishment of controls, criteria and research standards; collects and maintains preclinical study data effectively and efficiently for FDA submission; creates and keeps detailed and organized records of all in‑vivo research activities across various studies; has extensive knowledge in murine animal model experimentation, including injections (intramuscular, intraperitoneal, intravenous (tail vein and RO)), as well as blood collection techniques including cardiac puncture and cheek bleed, and tissue collection; murine colony management including breeding and weaning, mice tagging identification, monthly cage counting, record keeping, and euthanization; maintains accuracy of and compliance to IACUC protocol and ensures GLP conditions in IND‑enabling in‑vivo research studies; works closely with laboratory veterinarians and IACUC committee and staff to efficiently update the IACUC protocol as new studies are proposed and assists collaborators with IACUC protocol creation and adherence; manages lab spaces in accordance with IACUC and EHS regulations and leads IACUC and controlled substance inspections; assists in the preparation of research papers and manuscripts for publication and presentation at national and conferences and workshops, and in the writing of project reports, articles, and other documents; assists principal investigator in the preparation of proposals to obtain new or renewal of extramural funding in support of research; provides updates to PI and laboratory manager on progress of research.

Thank you for your interest in working at Ohio State.

Final candidates are subject to successful completion of a background check. A drug screen or physical may be required during the post offer process.

The university is an equal opportunity employer, including veterans and disability.