Researcher 1- Neurological Surgery

Ohio State University; Columbus (OH); On-site; USD 60,000 - 90,000; Full time

Job summary

Ohio State University seeks a Neurological Surgery Research Associate to participate in planning, design, execution, and management of all in-vivo research studies in a lab focused on translational pre-clinical therapies for CNS disorders.

You will lead necropsy, tissue collection, histology duties, data analysis, and ensure adherence to IACUC protocols while maintaining meticulous records across multiple studies. Collaboration with veterinarians and staff is essential.

Qualifications

• Experience planning, design, and management of in-vivo research studies.
• Proficient in necropsy techniques with leadership in lab necropsy functions.
• Maintains detailed records and GLP/IACUC protocol compliance.

Responsibilities

• Plan, design, and execute in-vivo studies in translational pre-clinical research.
• Lead necropsy procedures in small and large animals.
• Manage tissue collection, processing, and histology duties per study protocols.

Skills

Murine model experimentation

Necropsy techniques

Sample collection

Histology duties

Data analysis

IACUC compliance

Lab management

Record keeping

Animal handling

Job description

Researcher 1- Neurological Surgery Department: Medicine | Neurological Surgery Research Associate who participates in planning, design, execution, and management of all in-vivo research studies and activities in a research laboratory investigating translational pre-clinical studies in the development of AAV, drug-loaded liposomes, mRNA-based nanoparticles-based gene therapies for central nervous system disorders such as Parkinson's disease, Huntington's disease, AADC deficiency, Alzheimer's disease, lysosomal storage disorders, hearing loss, and depression in the Department of Neurological Surgery;

• participants in the execution of ongoing research projects;
• proficient in specialized necropsy techniques in small and large animals with the ability to lead necropsy function in the lab;
• leads efficient and high-quality sample collection, processing, tissue preservation and tissue trimming according to study protocols;
• assists with histology duties such as tissue processing, embedding, frozen sections, sorting, cutting, filing, reagent preparation, special stains, and staining slides of tissue samples;
• collects, analyzes, and interprets research data;
• assists in establishment of controls, criteria and research standards;
• collects and maintains preclinical study data effectively and efficiently for FDA submission;
• creates and keeps detailed and organized records of all in-vivo research activities across various studies;
• has extensive knowledge in murine animal model experimentation, including injections (intramuscular, intraperitoneal, intravenous (tail vein and RO)), as well as blood collection techniques including cardiac puncture and cheek bleed, and tissue collection;
• murine colony management including breeding and weaning, mice tagging identification, monthly cage counting, record keeping, and euthanization;
• maintains accuracy of and compliance to IACUC protocol and ensures GLP conditions in IND-enabling in-vivo research studies;
• works closely with laboratory veterinarians and IACUC committee and staff to efficiently update the IACUC protocol as new studies are proposed and assists collaborators with IACUC protocol creation and adherence;
• manages lab spaces in accordance with IACUC and EHS regulations and leads IACUC and controlled substance inspections;
• assists in the preparation of research papers and manuscripts for publication and presentation at national and conferences and workshops, and in the writing of project reports, articles, and other documents;
• assists principal investigator in the preparation of proposals to obtain new or renewal of extramural funding in support of research;
• provides updates to PI and laboratory manager on progress of research.

Additional Information

• Location: Pelotonia Research Center (1040)
• Position Type: Regular
• Scheduled Hours: 40
• Shift: First Shift
• Final candidates are subject to successful completion of a background check.
• A drug screen or physical may be required during the post offer process.

The university is an equal opportunity employer, including veterans and disability.

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Ohio State benefits give you options to take care of what matters most to you - and opportunities to make adjustments as your life and needs change, including:

• Medical, dental and vision coverage, with Ohio State paying a significant portion of the cost.
• Paid time off, including sick and vacation time and 11 holidays.
• State retirement plan or an alternative retirement plan, both with generous employer contributions.

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