Research Student

Partner's Healthcare; Boston (MA); On-site; USD 24,000 - 30,000; Full time

Job summary

The Brigham and Women's Hospital, Inc. is seeking a motivated Research Intern to assist in a range of experiments in a Cardiovascular Medicine lab.

The role involves working with zebrafish for colony maintenance and executing high-throughput screens for drug discovery, alongside in vitro and in vivo modeling to explore cardiovascular disorders. You will contribute to transcriptional, genetic, metabolic, and phenotypic profiling at multiple biological scales and support laboratory operations,

Qualifications

• High school diploma required.
• Currently enrolled in College/University majoring in biology/molecular genetics/biochemistry or related degree.

Responsibilities

• Maintenance and genotyping of zebrafish colonies.
• Analysis of zebrafish tissue including Western blotting, immunofluorescence microscopy, DNA purification and quantitative RT-PCR.
• Generation and purification of antibodies for ELISA assays for vascular biomarkers.
• Preparation and maintenance of tissue cultures.
• Preparation of laboratory reagents, chemicals, instruments and equipment.
• Chemical informatics.
• Time-lapse microscopy and automated image processing.

Skills

Good organizational skills

Team collaboration

Communication

Computer literacy

Data analysis

Attention to detail

Education

High school diploma

Currently enrolled in biology/molecular genetics/biochemistry or related degree

Job description

Site: The Brigham and Women's Hospital, Inc. Mass General Brigham relies on a wide range of professionals, including doctors, nurses, business people, tech experts, researchers, and systems analysts to advance our mission. As a not-for-profit, we support patient care, research, teaching, and community service, striving to provide exceptional care. We believe that high-performing teams drive groundbreaking medical discoveries and invite all applicants to join us and experience what it means to be part of Mass General Brigham.

Job Summary

A research lab within Brigham and Women's Cardiovascular Medicine division is looking for a motivated research intern to assist in a variety of research experiments. The lab uses both in vitro (human ESC/iPSC) and in vivo (zebrafish) techniques to model various cardiovascular disorders and integrates transcriptional, (epi)genetic, metabolic, and phenotypic profiling at whole organism, tissue, and single cell-level to fully understand the earliest molecular events characterizing disease onset, follow-up their dynamic changes over time, and to identify disease biomarkers. The research intern will be expected to help with all aspects of experimental work in the lab. This work will focus on zebrafish colony maintenance and using zebrafish to conduct high-throughput screens for drug discovery.

Qualifications

GENERAL SUMMARY/ OVERVIEW STATEMENT: A research lab within Brigham and Women's Cardiovascular Medicine division is looking for a motivated research intern to assist in a variety of research experiments. The lab uses both in vitro (human ESC/iPSC) and in vivo (zebrafish) techniques to model various cardiovascular disorders and integrates transcriptional, (epi)genetic, metabolic, and phenotypic profiling at whole organism, tissue, and single cell-level to fully understand the earliest molecular events characterizing disease onset, follow-up their dynamic changes over time, and to identify disease biomarkers. The research intern will be expected to help with all aspects of experimental work in the lab. This work will focus on zebrafish colony maintenance and using zebrafish to conduct high-throughput screens for drug discovery.

Principal Duties and Responsibilities

• Maintenance and genotyping of zebrafish colonies
• Analysis of zebrafish tissue including Western blotting, immunofluorescence microscopy, DNA purification and quantitative RT-PCR
• Generation and purification of antibodies for ELISA assays for vascular biomarkers
• Preparation and maintenance of tissue cultures
• Preparation of laboratory reagents, chemicals, instruments and equipment
• Chemical informatics
• Time-lapse microscopy and automated image processing

Qualifications

• High school diploma required
• Currently enrolled in a College/University majoring in biology/molecular genetics/biochemistry or related degree

Skills/Abilities/Competencies Required

• Good organizational skills, detail oriented
• Ability to communicate with multiple levels of staff and to work effectively with others in a team environment
• Ability to work independently when given an assignment
• Sound degree of computer literacy
• Ability to methodically record data and to assist in the analysis of data using basic statistics
• Ability to perform a variety of routine tests and prioritize work
• Good interpersonal and communication skills
• Ability to demonstrate professionalism

Working Conditions

Wet-lab/office setting.

Additional Job Details (if applicable):

• Remote Type: Onsite
• Work Location: 221 Longwood Avenue
• Scheduled Weekly Hours: 0
• Employee Type: Per Diem
• Work Shift: Day (United States of America)
• Pay Range: $17.50 - $21.80/Hourly
• Grade: 2

Pay and Benefits

At Mass General Brigham, we believe in recognizing and rewarding the unique value each team member brings to our organization. Our approach to determining base pay is comprehensive, and any offer extended will take into account your skills, relevant experience if applicable, education, certifications and other essential factors. The base pay information provided offers an estimate based on the minimum job qualifications; however, it does not encompass all elements contributing to your total compensation package. In addition to competitive base pay, we offer comprehensive benefits, career advancement opportunities, differentials, premiums and bonuses as applicable and recognition programs designed to celebrate your contributions and support your professional growth.

EEO Statement

2200 The Brigham and Women's Hospital, Inc. is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religious creed, national origin, sex, age, gender identity, disability, sexual orientation, military service, genetic information, and/or other status protected under law. We will ensure that all individuals with a disability are provided a reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. To ensure reasonable accommodation for individuals protected by Section 503 of the Rehabilitation Act of 1973, the Vietnam Veteran's Readjustment Act of 1974, and Title I of the Americans with Disabilities Act of 1990, applicants who require accommodation in the job application process may contact Human Resources at (857)-282-7642.

Mass General Brigham Competency Framework

At Mass General Brigham, our competency framework defines what effective leadership "looks like" by specifying which behaviors are most critical for successful performance at each job level. The framework is comprised of ten competencies (half People-Focused, half Performance-Focused) and are defined by observable and measurable skills and behaviors that contribute to workplace effectiveness and career success. These competencies are used to evaluate performance, make hiring decisions, identify development needs, mobilize employees across our system, and establish a strong talent pipeline.