Research Student

Mass General Brigham Incorporated; Boston, Northern (MA, KY); Hybrid; USD 23,000 - 29,000; Full time

Job summary

The Brigham and Women’s Cardiovascular Medicine division at Mass General Brigham is seeking a motivated research intern to assist in diverse experiments. The role focuses on zebrafish models for high-throughput drug discovery, integrating transcriptional, genetic, metabolic, and phenotypic profiling to understand disease onset and progression.

You will help with zebrafish colony maintenance, analyses, antibody work for biomarker assays, and general lab support in a wet-lab/office setting onsite

Qualifications

• High school diploma required or equivalent.
• Currently enrolled in biology/molecular genetics/biochemistry or related field.
• Familiarity with basic lab techniques and data analysis.

Responsibilities

• Maintenance and genotyping of zebrafish colonies.
• Analysis of zebrafish tissue including Western blotting, immunofluorescence microscopy, DNA purification and qRT-PCR.
• Generation and purification of antibodies for ELISA assays for vascular biomarkers.
• Preparation and maintenance of tissue cultures.
• Preparation of laboratory reagents, chemicals, instruments and equipment.
• Chemical informatics.
• Time-lapse microscopy and automated image processing.

Skills

Zebrafish handling

Laboratory techniques

Data recording

Teamwork

Computer literacy

Attention to detail

Communication

Education

High school diploma

Tools

Western blotting

Immunofluorescence

PCR

ELISA

Tissue culture

Microscopy

Job description

Site: The Brigham and women's Hospital, Inc. Mass General Brigham relies on a wide range of professionals, including doctors, nurses, business people, tech experts, researchers, and systems analysts to advance our mission. As a not-for-profit, we support patient care, research, teaching, and community service, striving to provide exceptional care. We believe that high-performing teams drive groundbreaking medical discoveries and invite all applicants to join us and experience what it means to be part of Mass General Brigham.

Job Summary

A research lab within Brigham and women's Cardiovascular Medicine division is looking for a motivated research intern to assist in a variety of research experiments. The lab uses both in vitro (human ESC/iPSC) and in vivo (zebrafish) techniques to model various cardiovascular disorders and integrates transcriptional, (epi)genetic, metabolic, and phenotypic profiling at whole organism, tissue, and single cell-level to fully understand the earliest molecular events characterizing disease onset, follow-up their dynamic changes over time, and to identify disease biomarkers. The research intern will be expected to help with all aspects of experimental work in the lab. This work will focus on zebrafish colony maintenance and using zebrafish to conduct high-throughput screens for drug discovery.

Principal Duties and Responsibilities

• Maintenance and genotyping of zebrafish colonies
• Analysis of zebrafish tissue including Western blotting, immunofluorescence microscopy, DNA purification and quantitative RT-PCR.
• Generation and purification of antibodies for ELISA assays for vascular biomarkers.
• Preparation and maintenance of tissue cultures.
• Preparation of laboratory reagents, chemicals, instruments and equipment.
• Chemical informatics.
• Time-lapse microscopy and automated image processing.

Qualifications

Required: High school diploma required. Currently enrolled in a College/University majoring in biology/molecular genetics/biochemistry or related degree.

Skills / Abilities / Competencies Required

• Good organizational skills, detail oriented
• Ability to communicate with multiple levels of staff and to work effectively with others in a team environment
• Ability to work independently when given an assignment.
• Sound degree of computer literacy
• Ability to methodically record data and to assist in the analysis of data using basic statistics
• Ability to perform a variety of routine tests and prioritize work
• Good interpersonal and communication skills
• Ability to demonstrate professionalism

Working Conditions

Wet-lab/office setting.

Additional Job Details (if applicable)

Remote Type Onsite Work Location 221 Longwood Avenue Scheduled Weekly Hours 0 Employee Type Per Diem Work Shift Day (United States of America) Pay Range $17.50 - $21.80/Hourly Grade 2

Compensation and Benefits

At Mass General Brigham, we believe in recognizing and rewarding the unique value each team member brings to our organization. Our approach to determining base pay is comprehensive, and any offer extended will take into account your skills, relevant experience if applicable, education, certifications and other essential factors. The base pay information provided offers an estimate based on the minimum job qualifications; however, it does not encompass all elements contributing to your total compensation package. In addition to competitive base pay, we offer comprehensive benefits, career advancement opportunities, differentials, premiums and bonuses as applicable and recognition programs designed to celebrate your contributions and support your professional growth.

EEO Statement

The Brigham and women's Hospital, Inc. is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religious creed, national origin, sex, age, gender identity, disability, sexual orientation, military service, genetic information, and/or other status protected under law. We will ensure that all individuals with a disability are provided a reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. To ensure reasonable accommodation for individuals protected by Section 503 of the Rehabilitation Act of 1973, the Vietnam Veterans Readjustment Act of 1974, and Title I of the Americans with Disabilities Act of 1990, applicants who require accommodation in the job application process may contact Human Resources at (857)-282-7642.

Mass General Brigham Competency Framework

At Mass General Brigham, our competency framework defines what effective leadership "looks like" by specifying which behaviors are most critical for successful performance at each job level. The framework is comprised of ten competencies (half People-Focused, half Performance-Focused) and are defined by observable and measurable skills and behaviors that contribute to workplace effectiveness and career success. These competencies are used to evaluate performance, make hiring decisions, identify development needs, mobilize employees across our system, and establish a strong talent pipeline.

Company Culture

Combat disease. Hold a hand. Help people. Impact the world. Mass General Brigham is a passionate, welcoming community where minds meet caring hearts. Come be a part of the world’s most powerful force in medicine, where every role is important in changing lives. Are you ready? Our history includes New England hospitals founded over 200 years ago, some of the first and most prestigious hospitals in the world. Built on the legacy of two leading academic medical centers, we’re more than a system—we’re leaders in the practice of medicine. Mass General Brigham is committed to serving the community. We are dedicated to enhancing patient care, teaching and research, and taking a leadership role as an integrated health care system. We recognize that increasing value and continuously improving quality are essential to maintaining excellence.