Research Scientist II, Cell Pharmacology - CVM

Novartis Group Companies; Cambridge (MA); On-site; USD 77,000 - 143,000; Full time

Job summary

An innovative firm in the biomedical research sector is seeking a motivated in vitro Research Scientist to join their Cell Pharmacology team. This role focuses on advancing the understanding of cardio-metabolic diseases through collaborative efforts in drug discovery. The successful candidate will engage in target identification, develop cell-based assays, and contribute to the optimization of new therapies. With a commitment to transforming lives, this position offers a dynamic environment where scientific expertise meets impactful research. Join a team dedicated to making a difference in patient care and health outcomes.

Benefits

Health Insurance

401(k)

Paid Time Off

Stock Units

Discretionary Awards

Qualifications

• 3+ years of relevant laboratory experience in industry or academia.
• Experience with cell culture and developing cell-based assays.

Responsibilities

• Support target identification and validation projects.
• Develop and perform cell-based assays for drug discovery.

Skills

Cell Culture

Molecular Biology

Data Analysis

Drug Discovery

Communication Skills

Analytical Skills

Education

Bachelor's degree in Biochemistry

Master's degree in a related field

Tools

qPCR

ELISA

RNAseq

Job description

Job Description Summary

Cardio-metabolic diseases result in the loss of about 17.9 million lives each year. The Cardiovascular and Metabolic Disease Area (CVM) of Biomedical Research is committed to changing this alarming statistic by discovering transformative medicines to treat cardiovascular and metabolic disorders.

We are seeking a highly motivated in vitro Research Scientist to join our Cell Pharmacology team. You will advance our understanding of disease biology, contribute to target identification efforts, and work towards the discovery and optimization of new drugs for CVM. The work involves collaboration with research scientists across multiple disciplines as well as translational medicine colleagues who support bringing our drugs to patients.

Job Description

Key Responsibilities:

1. Support target identification, validation and mechanism-of-action projects, including work with cell lines, primary cells, and/or tissues.
2. Devise, develop and perform cell-based assays for drug discovery. Occasionally, you will also employ molecular biology (e.g., qPCR, western blot), biochemical and biophysical techniques.
3. Support biology and pharmacology studies by developing and performing analysis of tissues derived from preclinical models supplied by our in vivo team.
4. Conduct data analyses and document experiments.
5. Collaborate effectively while working in a matrixed environment.
6. Employ good laboratory, data recording, and data documentation practices.
7. Present results in lab and department meetings.
8. Assist in writing research documents and publications.

Role Requirements:

1. Bachelor's degree in biochemistry, molecular or cell biology, biophysics, biomedical engineering or a related field; Master's degree preferred.
2. 3+ years of relevant laboratory experience in industry or academia.
3. A record of accomplishments with peer-reviewed publications is a plus.
4. Significant experience with cell culture is required.
5. Excellent communication (written and oral) and interpersonal skills, with the ability to work effectively in a matrixed team environment.
6. Experience in independently developing, executing, and troubleshooting cell-based assays for drug discovery is preferred.
7. Experience with qPCR, reporter assays, and ELISA is a plus but not required.
8. Experience with gene silencing (RNAi or CRISPR) or other target validation activities is a plus but not required.
9. Experience with RNAseq and other 'omics technologies is a plus but not required.

Additional Information:

#LI-Onsite

Compensation and Benefits:

The pay range for this position at the start of employment is expected to be between $77,000 and $143,000 per year. Salary ranges are effective from 01/01/2025 through 12/31/2025, but may be adjusted based on market conditions. Final pay will depend on various factors including location, experience, knowledge, skills, and abilities. The total compensation may include a sign-on bonus, stock units, discretionary awards, and benefits such as health insurance, 401(k), paid time off, etc. Details will be provided upon offer.

EEO Statement:

The Novartis Group of Companies is an Equal Opportunity Employer. We do not discriminate based on race, color, religion, sex, national origin, age, sexual orientation, gender identity, marital or veteran status, disability, or any other protected status.

Accessibility and Reasonable Accommodations:

We are committed to providing reasonable accommodations. If needed, contact us at [e-mail] or call [phone], including the job requisition number.

Salary Range:

$77,000 - $143,000

Skills Desired:

Algorithms, Analytical Skill, Chemical Biology, Clinical Research, Collaboration, Communication Skills, Curiosity, Data Analysis, Design Of Experiments, Diversity & Inclusion, Drug Discovery, Ethics, Hypothesis Testing, Immunology, Laboratory, Lifesciences, Mammalian Cell Culture, Medical Research, Molecular Biology, Organization, plus additional skills.