Research Scientist

Guidehouse; Bethesda (MD); On-site; USD 98,000 - 163,000; Full time

Benefits offered by this job

Medical, Rx, Dental & Vision Insurance

401(k) Retirement Plan

Paid Holidays & Sick Time

Tuition Reimbursement

Employee Referral Program

Learning Opportunities

Job summary

Guidehouse is seeking a Research Scientist to support NIH objectives in Bethesda, MD. The role involves immunology, molecular biology, sequencing, and tissue analysis, with collaboration across cores and regular presentations at meetings. It requires a Ph.D.

or MD and at least six years of relevant experience. The position is full-time, located in Bethesda, with travel up to 10% and opportunities to contribute to high-priority projects and scientific publications.

Qualifications

• Ph.D. or M.D. or related doctoral degree in science or medicine.
• Minimum of six years of research experience in science or related field.
• Extensive experience with molecular biology, biochemistry, immunology.
• Experience generating knockout mice and working with mouse models.
• Experience with next generation sequencing methods (RNA-seq, scRNA-seq, etc.).
• Ability to manage high-priority projects in a fast-paced environment.

Responsibilities

• Perform immunology, molecular biology techniques on cells/tissues.
• Execute sequencing, western blotting, and other assays.
• Present research at national/international meetings.
• Assist Lab Chief with documents (CRADAs, MTAs, etc.).
• Review papers and drafts for data presentation and policy adherence.
• Maintain mouse lines and coordinate projects.

Skills

Molecular biology

Immunology

Next-gen sequencing

Mouse models

Flow cytometry

Research project management

Education

Ph.D. or MD

Tools

ChIP

qPCR

RNA-seq

Job description

What You Will Do

We are currently searching for a Research Scientist. This role will independently provide support services to satisfy the overall operational objectives of the National Heart, Lung, and Blood Institute. The primary objective is to provide services and deliverables through performance of support services. This is a full-time opportunity located in Bethesda, MD.

• Perform a wide array of immunology and molecular biological techniques with animal and human cells/tissues.
• Perform a variety of biochemical assays, immuno-precipitations, polyacrylamide gel electrophoresis and western blotting.
• Perform a range of next generation sequencing techniques, including for transcriptomics and epigenetic analyses.
• Perform immunofluorescence staining and functional analyses of tissue samples.
• Work with the sequencing, mass spectrometry, flow cytometry, and other cores as needed.
• Present research at international and national research meetings.
• Conduct and help direct independent research projects of high priority for the laboratory.
• Assist the Lab Chief in the creating/preparing documents required by the Lab Chief’s scientific activities (e.g., CRADAs, Material Transfer Agreements, Patent Applications, Animal Protocols, BSC review)
• Review, edit, and write drafts of papers, posters and manuscripts produced within the laboratory for consistency of the research agenda, adherence to any applicable scientific policies, and clarity of presentation of data and other scientific information.
• Act as a scientific consultant, technical expert, and collaborator for IRTA fellows, Visiting Fellows, and others in the lab as needed.
• Maintain mouse lines (breeding, genotyping).

Job Family

Scientist

Travel Required

Up to 10%

Clearance Required

Ability to Obtain Public Trust

What You Will Need

• Ph.D. or M.D. or other appropriate doctoral degree in science, medicine, or related field
• Minimum of SIX (6) years of research experience in science, medicine, or related fields.
• Extensive experience in molecular biology, biochemistry, and immunology research, including experience in immune cell development and function.
• Experience generating knockout mice, conditional knockout mice, and extensive experience working with mice/mouse models.
• Extensive experience related to next generation sequencing methods and analyses (e.g., RNA-seq, scRNA-seq, ChIP-seq, ATAC-seq, Hi-C, HiChIP, PCA, UMAP, tSNE).
• Experience with advanced molecular biology techniques (e.g., ChIP, co-IP, advanced cloning techniques, western blotting, Northern blotting, Southern blotting, Q-PCR).
• Experience with flow cytometry, immunohistochemistry, and metabolomics.
• Extensive experience in cell culture and/or extensive knowledge of cell biology.
• Ability to manage and coordinate high-priority short- and long-term projects and studies in a fast-paced environment.

What Would Be Nice To Have

• Previous experience with NIH preferred.
• Proficient in Microsoft Office and PowerPoint

The annual salary range for this position is $98,000.00-$163,000.00. Compensation decisions depend on a wide range of factors, including but not limited to skill sets, experience and training, security clearances, licensure and certifications, and other business and organizational needs.

What We Offer

Guidehouse offers a comprehensive, total rewards package that includes competitive compensation and a flexible benefits package that reflects our commitment to creating a diverse and supportive workplace.

Benefits Include

• Medical, Rx, Dental & Vision Insurance
• Personal and Family Sick Time & Company Paid Holidays
• Parental Leave
• 401(k) Retirement Plan
• Group Term Life and Travel Assistance
• Voluntary Life and AD&D Insurance
• Health Savings Account, Health Care & Dependent Care Flexible Spending Accounts
• Transit and Parking Commuter Benefits
• Short-Term & Long-Term Disability
• Tuition Reimbursement, Personal Development, Certifications & Learning Opportunities
• Employee Referral Program
• Corporate Sponsored Events & Community Outreach
• Care.com annual membership
• Employee Assistance Program
• Supplemental Benefits via Corestream (Critical Care, Hospital Indemnity, Accident Insurance, Legal Assistance and ID theft protection, etc.)
• Position may be eligible for a discretionary variable incentive bonus

About Guidehouse

Guidehouse is an Equal Opportunity Employer–Protected Veterans, Individuals with Disabilities or any other basis protected by law, ordinance, or regulation.

Guidehouse will consider for employment qualified applicants with criminal histories in a manner consistent with the requirements of applicable law or ordinance including the Fair Chance Ordinance of Los Angeles and San Francisco.

If you have visited our website for information about employment opportunities, or to apply for a position, and you require an accommodation, please contact Guidehouse Recruiting at 1-571-633-1711 or via email at [e-mail]. All information you provide will be kept confidential and will be used only to the extent required to provide needed reasonable accommodation.

All communication regarding recruitment for a Guidehouse position will be sent from Guidehouse email domains including @guidehouse.com or [e-mail]. Correspondence received by an applicant from any other domain should be considered unauthorized and will not be honored by Guidehouse. Note that Guidehouse will never charge a fee or require a money transfer at any stage of the recruitment process and does not collect fees from educational institutions for participation in a recruitment event. Never provide your banking information to a third party purporting to need that information to proceed in the hiring process.

If any person or organization demands money related to a job opportunity with Guidehouse, please report the matter to Guidehouse’s Ethics Hotline. If you want to check the validity of correspondence you have received, please contact [e-mail]. Guidehouse is not responsible for losses incurred (monetary or otherwise) from an applicant’s dealings with unauthorized third parties.