Research Postdoctoral Fellow II

The Chronicle Of Higher Education, Inc.; Houston (TX); On-site; USD 60,000 - 90,000; Full time

Job summary

An academic institution in Texas seeks a researcher in pharmaceutical science to conduct bioanalysis, drug metabolism studies, and mentor students. Candidates should have a Doctoral degree in biomedical science with research experience. Responsibilities include supporting grant writing, maintaining lab instruments, and presenting research at meetings. Ideal candidates will have experience with analytical instruments and will produce peer-reviewed publications. The role offers an opportunity to contribute to significant grants and research initiatives.

Qualifications

• Doctoral degree with experience in pharmaceutical research required.
• Expertise in biostatistical analysis supporting biomedical research.
• Preferred: 3 peer-reviewed publications as a primary author.

Responsibilities

• Conduct bioanalysis and drug absorption studies.
• Lead advanced drug metabolism research and prepare assays.
• Assist with grant writing and present research findings.

Skills

Biostatistical analysis

Technical and functional principles

Details oriented

Problem-solving

Time management

Verbal communication

Written communication

Education

Doctoral degree in biomedical science

Tools

Waters Acquity UPLC

Sciex tripleQ

LC-MS/MS equipment

Job description

Job Description Summary

Under direct supervision of the U54 grant P, this position conducts pharmaceutical science research in the Center for Biomedical and Health Research (CBMHR). Specifically, responsible for bioanalysis, drug absorption using the Caco-2 cell culture model and intestinal perfusion model, drug metabolism using enzyme-mediated models, metabolite structure identification, drug elimination and biodistribution using animal models, providing the relevant services and technical support to internal and external users. In addition, this position is responsible for supporting the research and development activities of the university’s large center grants, including the NIH U54 RCMI-CBMHR Center, CPRIT CCPF Center, the iO3 Center, and TSU’s Catalyst. Assists in grant and paper writing, and presents research at local, national and international meetings. Provides help in lab maintenance. This is a grant funded position.

Essential Duties

• Responsible for operating, maintaining instruments and conducting bioanalysis using Waters Acquity UPLC and Sciex tripleQ and high-resolution LC-MS/MS equipment in the RCMI-CBMHR core facility.
• Conduct drug absorption studies using the Caco-2 cell culture, transporter vesicle membrane, and intestinal perfusion models.
• Lead advanced drug metabolism research, including the preparation and characterization of tissue microsomes, development of in vitro metabolism assays, and evaluation of metabolic pathways and enzyme kinetics. Metabolite structure identification using LC-MS, NMR, etc.
• Complete cell culture for in vitro ADME studies ensuring compliance with best practices, quality standards, and safety regulations.
• Maintains all CBMHR instruments, develops and implements comprehensive record-keeping and compliance frameworks on program participants, staff, equipment inventories and compliance activities.
• Prepare and review facility activity reports, including research activity summaries, operational status documents, instrument usage statistics, and program status to the users, university and funding agencies.
• Assist PIs in preparation of progress reports and grant deliverables, ensuring scientific accuracy and timely submission.
• Publishes data and publications in peer-reviewed journals, presents at conferences, and actively pursues external funding opportunities.
• Provide advanced training, mentorship, and supervision to undergraduate and graduate students, technical staff, and junior scientists in research skills.
• Performs other job‑related duties as assigned.

Education

Required: Doctoral degree in biomedical science‑related field with experience in pharmaceutical research.

Required Knowledge, Skills, and Abilities

Knowledge of:

• Biostatistical analysis supporting biomedical/pharmaceutical research.
• Technical and functional principles and procedures.
• Microsoft Office Professional or similar applications.

Skill In:

• Details oriented.
• Problem‑solving and decision‑making.
• Multitasking and time management.
• Writing documents.
• Both verbal and written communication.

Ability to

• Operate software.
• Maintain the security or integrity of critical infrastructure, which may include communications systems, computer networks and systems, cybersecurity systems, electrical grids, hazardous waste treatment, or water treatment systems.

Preferred Work Experience

• A preferred candidate should have at least 3 peer‑reviewed publications as the primary author.
• Preferred experience with analytical instrumentation, ADME and PK research, and animal handling experience, medicinal chemistry, etc.

Working and Environmental Conditions

Work is performed within a routine office environment with no exposure to hazardous or unpleasant conditions. Physical demands are usually limited to sitting or standing in one location for much of the time. Some stooping, lifting or carrying objects of light weight may be required.

UA EEO Statement

It is the policy of Texas Southern University to provide a work environment that is free from discrimination for all persons regardless of race, color, religion, sex, age, national origin, individuals with disability, sexual orientation, or protected veteran status in its programs, activities, admissions or employment policies. This policy of equal opportunity is strictly observed in all University employment‑related activities such as advertising, recruiting, interviewing, testing, employment training, compensation, promotion, termination, and employment benefits. This policy expressly prohibits harassment and discrimination in employment based on race, color, religion, gender, gender identity, genetic history, national origin, individuals with disability, age, citizenship status, or protected veteran status. This policy shall be adhered to in accordance with the provisions of all applicable federal, state and local laws, including, but not limited to, Title VII of the Civil Rights Act.