Research Fellow - Gerontology

Advocate Health; Winston-Salem (NC); On-site; USD 60,000 - 90,000; Full time

Job summary

Wake Forest University School of Medicine in Winston-Salem, NC, invites applications for a NIH-funded postdoctoral position in the laboratory of Dr. Bumsoo Ahn to study mitochondrial bioenergetics and muscle adaptation in aging and cancer.

The fellow will lead research integrating cell culture, in vivo mouse models, functional phenotyping, and mechanistic bioenergetic analyses, with strong mentorship toward career development and opportunities for first-author publications.

Qualifications

• PhD required in a relevant field or closely related discipline.
• Experience with cell culture, animal handling, dissections, and molecular methods (qRT-PCR, Western blot).
• Excellent oral and written communication skills.

Responsibilities

• Design and implement interventions that modulate mitochondrial bioenergetics and redox balance.
• Conduct cell culture, rodent behavioral and functional assessments.
• Perform mitochondrial bioenergetic assessments (Seahorse or Oroboros).
• Coordinate redox and proteomic analyses.
• Analyze data with a multidisciplinary team.
• Contribute to manuscript preparation and grant development.

Skills

Cell culture

Mouse handling

Molecular biology

Imaging

Education

PhD in physiology, molecular biology, biochemistry, neuroscience, cancer biology, or related field

Tools

Seahorse Bioscience

Oroboros O2k

Job description

Job Summary

An NIH-funded postdoctoral position is available in the laboratory of Dr. Bumsoo Ahn at Wake Forest University School of Medicine to investigate mitochondrial bioenergetics and muscle adaptation in models of aging and cancer.

The fellow will lead a line of research examining how interventions that modulate mitochondrial bioenergetics influence muscle performance, energetic reserve, and physiological responses to stress. Projects will integrate cell culture, in vivo mouse models, functional phenotyping, and mechanistic bioenergetic analyses, with flexibility to pursue emerging directions as new findings arise. This position offers strong opportunities for first-author publications and provides structured mentorship toward competitive career development funding within a collaborative and translational research environment focused on aging and muscle biology.

Basic Qualifications

• Applicants with no more than two years' experience after completing a PhD in physiology, molecular biology, biochemistry, neuroscience, cancer biology, or a related field.
• Proficiency in cell culture, mouse handling, microdissections, and molecular biology techniques (i.e., qRT-PCR, western blot and imaging)
• Excellent oral and written communication skills

Responsibilities

The postdoctoral fellow will:

• Design and implement interventions that modulate mitochondrial bioenergetics and redox balance, including voluntary wheel running and ghrelin administration via osmotic pump.

• Conduct cell culture, rodent behavioral and functional assessments, including motor and cognitive testing.
• Perform mitochondrial bioenergetic assessments using Seahorse Bioscience or Oroboros O2k high resolution respirometry
• Coordinate redox and proteomic analyses.
• Analyze and interpret data in collaboration with a multidisciplinary team.
• Contribute to manuscript preparation and grant development.

Research Environment

The Ahn laboratory conducts mechanistic and translational research focused on mitochondrial bioenergetics, redox signaling, aging, and resilience. The fellow will work within a collaborative environment that includes clinical oncologists, behavioral neuroscientists, proteomics experts, and biostatisticians. The position offers strong mentorship in experimental design, high-impact publication strategy, and NIH career development pathways.

#WFUSM