Postdoc: Mitochondrial Bioenergetics in Aging & Muscle

Hugh Chatham Health; Winston-Salem (NC); On-site; USD 64,000 - 96,000; Full time

Benefits offered by this job

Paid Time Off

Health benefits

Flexible Spending Accounts

Family benefits

Retirement plan with employer match

Educational assistance

Job summary

Advocate Health's Wake Forest University Health Sciences - Gerontology invites applications for an NIH-funded postdoctoral position in the laboratory of Dr. Bumsoo Ahn at Wake Forest University School of Medicine to study mitochondrial bioenergetics and muscle adaptation in aging and cancer models.

The fellow will lead a line of research integrating cell culture, in vivo mouse models, functional phenotyping, and mechanistic bioenergetic analyses, with flexibility to pursue emerging directions.

Qualifications

• Applicants with no more than two years' experience after completing a PhD in physiology, molecular biology, biochemistry, neuroscience, cancer biology, or a related field.
• Proficiency in cell culture, mouse handling, microdissections, and molecular biology techniques (i.e., qRT-PCR, western blot and imaging)
• Excellent oral and written communication skills

Responsibilities

• Design and implement interventions that modulate mitochondrial bioenergetics and redox balance, including voluntary wheel running and ghrelin administration via osmotic pump.
• Conduct cell culture, rodent behavioral and functional assessments, including motor and cognitive testing.
• Perform mitochondrial bioenergetic assessments using Seahorse Bioscience or Oroboros O2k high resolution respirometry
• Coordinate redox and proteomic analyses.
• Analyze and interpret data in collaboration with a multidisciplinary team.
• Contribute to manuscript preparation and grant development

Skills

Cell culture

Mouse handling

Molecular biology techniques

qRT-PCR

Western blot

Imaging

Oral and written communication

Education

PhD in physiology, molecular biology, biochemistry, neuroscience, cancer biology or related field

Tools

Seahorse Bioscience

Oroboros O2k

Job description

Advocate Health's Wake Forest University Health Sciences - Gerontology invites applications for an NIH-funded postdoctoral position in the laboratory of Dr. Bumsoo Ahn at Wake Forest University School of Medicine to study mitochondrial bioenergetics and muscle adaptation in aging and cancer models.

The fellow will lead a line of research integrating cell culture, in vivo mouse models, functional phenotyping, and mechanistic bioenergetic analyses, with flexibility to pursue emerging directions.