Research Fellow

Michigan Medicine; Ann Arbor (MI); On-site; USD 58,000 - 72,000; Full time

Job summary

Michigan Medicine's Truttmann laboratory at the University of Michigan seeks to hire a postdoctoral research fellow to join the team focusing on ER proteostasis in aging and aging-associated diseases. We use models like C.

elegans, mouse, and iPSCs, and techniques such as gene editing, nanobody generation, and small molecule screens to identify and target novel mechanisms of protein misfolding. The ideal candidate will bring new expertise, collaborate, and develop their own scientific niche,

Qualifications

• PhD in genetics, cell biology, biochemistry, or related field.
• Excellent written and verbal communication skills, as well as interpersonal skills contributing to a strong team environment.
• Basic molecular biology expertise and familiarity with imaging microscopy techniques.
• Previous experience working with animal and/or cell-based experimental models.
• Previous first author publication(s).
• Strong letters of support from at least one mentor and one mentee.
• Previous experience using C.elegans, iPSCs, and/or murine models to study proteostasis.
• Clear career vision with a distinct plan for what skills and data they would like to acquire during this fellowship.

Responsibilities

• Design experiments
• Direct data generation and analysis
• Apply for independent funding (with PI support)
• Write research manuscripts and reviews (with PI input)
• Present experimental results internally and at scientific meetings
• Train new lab members in routine experimental procedures
• Mentor and provide leadership to other lab members including graduate students, undergraduate students, and staff technicians

Skills

Written and verbal communication

Molecular biology

Imaging microscopy

Animal and cell models

First author publications

Education

PhD in genetics, cell biology, biochemistry, or related field

Job description

Job Summary

The Truttmann laboratory at the University of Michigan seeks to hire a postdoctoral research fellow to join the team. The lab is interested in ER proteostasis regulation in aging and aging-associated diseases. We use a combination of models (e.g. C. elegans, mouse, iPSCs) and techniques (e.g. gene editing, nanobody generation, small molecule screens) to identify, assess, and target novel mechanisms to mitigate aging-associated protein misfolding. Our current main focus is to study the human AMPylase, FICD, in the context of distinct protein misfolding diseases. For more information visit https://truttmann.lab.medicine.umich.edu/.

Job Summary

The Truttmann laboratory at the University of Michigan seeks to hire a postdoctoral research fellow to join the team. The lab is interested in ER proteostasis regulation in aging and aging-associated diseases. We use a combination of models (e.g. C. elegans, mouse, iPSCs) and techniques (e.g. gene editing, nanobody generation, small molecule screens) to identify, assess, and target novel mechanisms to mitigate aging-associated protein misfolding. Our current main focus is to study the human AMPylase, FICD, in the context of distinct protein misfolding diseases. For more information visit https://truttmann.lab.medicine.umich.edu/.

Our group values curiosity, teamwork, community, and the desire for intellectual growth. We are looking for an individual interested in contributing to the lab's ongoing research projects, while also develop their own scientific niche. An ideal candidate will bring new expertise and experience to the lab, while showing interest in learning new skills to expand their portfolio.

What You'll Do

• Design experiments
• Direct data generation and analysis
• Apply for independent funding (with PI support)
• Write research manuscripts and reviews (with PI input)
• Present experimental results internally and at scientific meetings
• Train new lab members in routine experimental procedures
• Mentor and provide leadership to other lab members including graduate students, undergraduate students, and staff technicians
• Train new lab members in routine experimental procedures
• Mentor and provide leadership to other lab members including graduate students, undergraduate students, and staff technicians

Required Qualifications*

• PhD in genetics, cell biology, biochemistry, or related field
• Excellent written and verbal communication skills, as well as interpersonal skills contributing to a strong team environment
• Basic molecular biology expertise and familiarity with imaging microscopy techniques
• Previous experience working with animal and/or cell-based experimental models
• Previous first author publication(s)
• Strong letters of support from at least one mentor and one mentee

Desired Qualifications*

• Previous experience using C.elegans, iPSCs, and/or murine models to study proteostasis
• Clear career vision with a distinct plan for what skills and data they would like to acquire during this fellowship

Background Screening

Michigan Medicine conducts background screening and pre-employment drug testing on job candidates upon acceptance of a contingent job offer and may use a third party administrator to conduct background screenings. Background screenings are performed in compliance with the Fair Credit Report Act. Pre-employment drug testing applies to all selected candidates, including new or additional faculty and staff appointments, as well as transfers from other U-M campuses.

Application Deadline

Job openings are posted for a minimum of seven calendar days. The review and selection process may begin as early as the eighth day after posting. This opening may be removed from posting boards and filled any time after the minimum posting period has ended.

U-M EEO Statement

The University of Michigan is an Equal Opportunity Employer. We are committed to providing an environment of mutual respect where equal employment opportunities are available to all applicants, including protected veterans and individuals with disabilities.