Research Associate - Structural Biologist

University of Texas; Austin (TX); On-site; USD 62,000 - 78,000; Full time

Job summary

University of Texas invites applications for a Research Associate in Structural Biology in Austin, TX. The role focuses on biochemical and structural studies of reverse transcriptase and related enzymes, with protein purification, crystallography, and cryo-EM analysis to obtain structural insights.

Responsibilities include expressing and characterizing proteins, designing experiments, writing manuscripts, and mentoring graduate students. Immediate start date; 40-hour week; exempt.

Qualifications

• PhD in structural biology and/or biochemistry with demonstrated productivity.

Responsibilities

• Express, purify, and characterize full-length and deletion constructs for structural analysis.
• Characterize wild-type and mutant proteins via enzymatic assays.
• Determine conditions for diffraction quality crystals or cryo-EM analysis.
• Obtain structures of reverse transcriptase and related enzymes with nucleic acid-protein complexes.
• Write manuscripts and assist with reports, abstracts, and proposals.
• Provide instruction, mentoring to graduate students.

Skills

Structural biology

Biochemistry

Protein purification

X-ray crystallography

Cryo-EM

Enzymatic assays

Biophysical assays

Mentoring

Team collaboration

Education

PhD in structural biology/biochemistry

Tools

FPLC

X-ray diffraction

Cryo-EM

Job description

## Research Associate - Structural BiologistApplylocations: AUSTIN, TXtime type: Full timeposted on: Posted Todayjob requisition id: R\_00047389**Job Posting Title:**Research Associate - Structural Biologist**----****Hiring Department:**Molecular Biosciences**----****Position Open To:**All Applicants**----****Weekly Scheduled Hours:**40**----****FLSA Status:**Exempt from FLSA**----****Earliest Start Date:**Immediately**----****Position Duration:**Expected to Continue Until Jul 16, 2027**----****Location:**AUSTIN, TX**----****Job Details:****Purpose**Carry out research in structural biology and biochemistry of reverse transcriptase and related enzymes and their nucleic acid complexes.**Responsibilities*** Express, purify, and characterize full-length and deletion constructs of group II intron and other non-LTR retroelement reverse transcriptase and related proteins for structural analysis and biotechnological applications using Fast Protein Liquid Chromatography FPLC and other methods. Characterize wild-type and mutant proteins biochemically via enzymatic assays and determine conditions for obtaining diffraction quality crystals and/or for cryo-electron microscopy analysis of proteins and protein/nucleic acid complexes. Carry out biochemical and biophysical assays.* Obtain structures of reverse transcriptase and related enzymes and their nucleic acid-protein complexes by X-ray diffraction and/or cryo-EM structures.* Write manuscripts and assist in the preparation of reports, abstracts, manuscripts and proposals. Make presentations at lab meetings. Attend lab meetings and other meetings. Order chemicals and supplies specific to current project.* Provide instruction, assistance and mentoring to graduate students.## Required QualificationsPh.D. in structural biology and/or biochemistry with demonstrated productivity in these areas.*Relevant education and experience may be substituted as appropriate.*## Preferred QualificationsPh.D. in structural biology and/or biochemistry with at least three years’ experience and demonstrated research productivity on enzymes that bind nucleic acids and/or protein-nucleic acid complexes## Salary Range$62,000 + depending on qualifications## Working Conditions* Personal protection equipment (furnished)* May work around chemical fumes* May work around standard office conditions* May work around bio-hazards* May work around chemicals## Required Materials* Resume/CV* Minimum of three letters of reference, at least two of which must be from referees outside of the University of Texas at Austin* Letter of interest**Important** **for applicants who are NOT current university employees or contingent workers:** You will be prompted to submit your resume the first time you apply, then you will be provided an option to upload a new Resume for subsequent applications. Any additional Required Materials (letter of interest, references, etc.) will be uploaded in the Application Questions section; you will be able to multi-select additional files. Before submitting your online job application, ensure that ALL Required Materials have been uploaded. Once your job application has been submitted, you cannot make changes.**Important for Current university employees and contingent workers:** As a current university employee or contingent worker, you MUST apply within Workday by searching for Find UT Jobs. If you are a current University employee, log-in to Workday, navigate to your Worker Profile, click the Career link in the left hand navigation menu and then update the sections in your Professional Profile before you apply. This information will be pulled in to your application. The application is one page and you will be prompted to upload your resume. In addition, you must respond to the application questions presented to upload any additional Required Materials (letter of interest, references, etc.) that were noted above.----**Employment Eligibility:**Regular staff who have been employed in their current position for the last six continuous months are eligible for openings being recruited for through University-Wide or Open Recruiting, to include both promotional opportunities and lateral transfers. Staff who are promotion/transfer eligible may apply for positions without supervisor approval.----**Retirement Plan Eligibility:**The retirement plan for this position is Teacher Retirement System of Texas (TRS), subject to the position being at least 20 hours per week and at least 135 days in length. This position has the option to elect the Optional Retirement Program (ORP) instead of TRS, subject to the position being 40 hours per week and at least 135 days in length.----**Background Checks:**A criminal history background check will be required for finalist(s) under consideration for this position.----**Equal Opportunity Employer:**The University of Texas at Austin, as an equal opportunity/affirmative action employer, complies with all applicable federal and state laws regarding nondiscrimination and affirmative action. The University is committed to a policy of equal opportunity for all persons and does not discriminate on the basis of race, color, national origin, age, marital status, sex, sexual orientation, gender identity, gender expression, disability, religion, or veteran status in employment, educational programs and activities, and admissions.----**Pay Transparency:**The University of Texas at Austin will not discharge or in any other manner discriminate against employees or applicants because they have inquired about, discussed, or disclosed their own pay or the pay of another employee or applicant. However, employees who have access to the compensation information of other employees or applicants as a part of their essential job functions cannot disclose the pay of other employees or applicants to individuals who do not otherwise have access to compensation information, unless the disclosure is (a) in response to a formal complaint or charge, (b) in furtherance of an investigation, proceeding, hearing, or action, including an investigation conducted by the employer, or (c) consistent with the contractor’s legal duty to furnish information.----**Employment Eligibility Verification:**If hired, you will be required to complete the federal Employment Eligibility Verification I-9 form. You will be required to present acceptable and original documents to prove your identity and authorization to work in the United States. Documents need to be presented no later than the third day of employment. Failure to do so will result in loss of employment at the university.**----****E-Verify:**The University of Texas at Austin use E-Verify to check the work authorization of all new hires effective May 2015. The university’s company ID number for purposes of E-Verify is 854197. For more information about E-Verify, please see the following:* E-Verify Poster (English and Spanish) [PDF]* Right to Work Poster (English) [PDF]* Right to Work Poster (Spanish) [PDF]**----****Compliance:**Employees may be required to report violations of law under Title IX and the Jeanne Clery Disclosure of Campus Security Policy and Crime Statistics Act (Clery Act). If this position is identified a Campus Security Authority (Clery Act), you will be notified and provided resources for reporting. Responsible employees under Title IX are defined and outlined in HOP-3031.The Clery Act requires all prospective employees be notified of the availability of the Annual Security and Fire Safety report. You may access the most recent report here or obtain a copy at University Compliance Services, 1616 Guadalupe Street, UTA 2.206, Austin, Texas 78701.