Research Associate II - Hematologic Malignancies

City of Hope; Duarte (CA); On-site; USD 65,000 - 90,000; Full time

Job summary

City of Hope invites applications for a Research Associate II within the lab of Dr. Yaling Yang.

The role focuses on the molecular pathogenesis and therapeutic targeting of hematologic malignancies, including T-ALL and AML, using leukemia models and techniques such as fluorescence microscopy, proteomics, RNAseq, and CRISPR-Cas9. Under supervision, the RAII conducts research, coordinates with the supervisor on project scope, trains staff, and contributes to research design and safety compliance.

Qualifications

• Bachelor’s degree required; Master’s degree preferred.
• Two years related research/lab experience with a Bachelor’s degree or one year related research/lab experience with a Master’s degree.

Responsibilities

• Perform routine and non-routine laboratory research experiments; record and validate results.
• Troubleshoot procedures; recommend alternative procedures.
• Record work including results and methodology; analyze data.
• Independently evaluate data and contribute to overall research design; train staff on procedures.
• Contribute to manuscripts by describing methods; stay updated on new techniques.
• Ensure laboratory activities comply with safety procedures and guidelines for handling hazardous materials.

Education

Bachelor’s degree

Master’s degree (preferred)

Tools

CRISPR-Cas9

Job description

Join the forefront of groundbreaking research at City of Hope where we're changing lives and making a real difference in the fight against cancer, diabetes, and other life-threatening illnesses. Our dedicated and compassionate faculty and staff are driven by a common mission: Contribute to innovative approaches in predicting, preventing, and curing diseases, shaping the future of medicine through cutting‑edge research.

A Research Associate II is available within the lab of Dr. Yaling Yang. The Yang research lab focuses on the molecular pathogenesis and therapeutic targeting of hematologic malignancies, particularly T-cell acute lymphoblastic leukemia/lymphoma (T-ALL) and acute myeloid leukemia (AML). Research involves the use of leukemia models, and techniques such as fluorescence microscopy, proteomics, RNAseq, and CRISPR-Cas9.

Under general supervision of the Principal Investigator, or designee, the Research Associate II (RAII) directs the work of a laboratory or undertakes research projects in collaboration with academic supervisor, making innovative contributions pertaining to laboratory procedures which may not change the course of an investigation but do indicate significant independent contribution beyond the RA I level. RAII typically consults with the academic supervisor on the scope and plan of approach to a research project; reads abstracts and articles; organize and plan techniques; plan and assign the work of at least one lab staff advising on problems they are unable to solve; contribute original ideas to the laboratory research; standardize new techniques and train staff on these techniques; perform specialized procedures and prepare written reports of laboratory experimental methods.

As a successful candidate, you will:

• Perform a variety of routine and non‑routine laboratory research experiments. Record and validate results for accuracy and completeness.
• Troubleshoot procedures if experiment results are unexpected or unsatisfactory. Recommend alternative procedures.
• Accurately record work performed including results and methodology. Calculate, compile, and analyze data obtained from work performed.
• Independently evaluate research data and initiate alternative approaches to improve the quality of results by providing input to overall research design. Train lab staff in specialized procedures, equipment, and theoretical concepts behind unique tests.
• May contribute to the preparation of manuscripts by describing methods and specialized techniques. Keep abreast of new and improved techniques.
• Ensure that all laboratory activities are carried out in compliance with each procedure(s) by utilizing safety procedures and guidelines in handling, storage and disposal of bio‑hazardous, infectious and toxic material.

Your qualifications should include:

• Bachelor’s degree. Master’s degree preferred.
• Two years related research/ laboratory experience with a Bachelor’s degree or one year related research/ laboratory experience with a Master’s degree.

City of Hope employees pay is based on the following criteria: work experience, qualifications, and work location.

City of Hope is an equal opportunity employer.

To learn more about our Comprehensive Benefits, please.

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