Translational Scientist, Hematologic Malignancies

City of Hope; California (MO); On-site; USD 54,000 - 182,000; Full time

Job summary

City of Hope, a leading research and treatment institution, seeks a Staff Scientist for translational studies in hematologic malignancies. The role involves in vivo modeling, flow cytometry, genomic and transcriptomic analyses, and collaboration with clinical teams to advance diagnostics and therapies.

You will design experiments, supervise lab operations, mentor junior staff, and maintain meticulous records while adhering to safety and regulatory standards.

Qualifications

• PhD, MD, or MD/PhD in a biomedical field with at least 3 years' hands-on experience in hematologic malignancies.
• Expertise in data analysis and immunophenotyping; cell sorting experience desirable.
• Experience designing experiments with mouse models, primary human samples, and genomic profiling tools (NGS, RNA-seq).
• Proven leadership in mentoring junior staff and managing laboratory operations.

Responsibilities

• Design and execute experiments with mouse models, patient samples, and molecular assays.
• Develop and optimize protocols for studying disease mechanisms and diagnostic refinement.
• Analyze data and collaborate with bioinformatics staff when necessary.
• Troubleshoot laboratory equipment and coordinate maintenance and QC.
• Work with team to design experiments, interpret findings, and contribute to manuscript and grant preparation.
• Communicate results to faculty, trainees, and clinical collaborators; participate in team meetings.
• Provide mentorship and training to junior lab members.
• Maintain meticulous records and ensure data reproducibility.
• Adhere to safety regulations for human samples and animal models.

Skills

Immunophenotyping

Mouse models

Data analysis

Mentoring / leadership

Study design

Project coordination

Communication

Laboratory safety

Education

PhD, MD, or MD/PhD in biomedical field

Tools

Flow cytometry

NGS

RNA-Seq

Cell sorting

Job description

City of Hope, a leading research and treatment institution, seeks a Staff Scientist for translational studies in hematologic malignancies. The role involves in vivo modeling, flow cytometry, genomic and transcriptomic analyses, and collaboration with clinical teams to advance diagnostics and therapies.

You will design experiments, supervise lab operations, mentor junior staff, and maintain meticulous records while adhering to safety and regulatory standards.