Research Associate - Chemical Development

Novo Nordisk; Boulder (CO); On-site; USD 110,000 - 150,000; Full time

Job summary

Chemical Development Scientist at Novo Nordisk's Boulder site focuses on scalable synthesis of oligonucleotides and RNAi therapeutics. You will develop and optimize chemical processes, investigate reaction conditions, purification, and characterization while supporting tech transfer and collaboration with internal teams and partners.

Ideal candidates have a background in synthetic organic chemistry and analytical methods (HPLC, LC-MS, NMR) with strong problem-solving and communication skills,

Qualifications

• BA/BS or MS in Chemistry, Biology, or related field.
• Entry level: no experience required; senior roles: 8+ years lab experience.

Responsibilities

• Develop and optimize chemical processes for oligonucleotide production; support process improvements for manufacturing; document findings and collaborate with internal teams and external partners.

Skills

Synthetic organic chemistry

HPLC

LC-MS

NMR

Oligonucleotide synthesis

Education

BS/MS in Chemistry or related field

Job description

Role

Chemical Development Scientist supporting scalable synthesis of oligonucleotides and RNAi therapeutics at Novo Nordisk's Boulder site.

Responsibilities

• Develop and optimize chemical processes for oligonucleotide production, including reaction conditions, purification, and characterization; support process improvements for manufacturing; document findings and collaborate with internal teams and external partners.

Requirements

• BA/BS or MS in Chemistry, Biology, or related field; for entry-level, no experience required; for senior roles, 8+ years relevant lab experience.

Skills

• expertise in synthetic organic chemistry, oligonucleotide synthesis, analytical techniques (HPLC, LCMS, NMR); strong problem-solving, detail orientation, and communication skills; ability to work independently and in teams.

High-Value

focus on oligonucleotides and RNAi therapeutics, process development, scale-up, tech transfer, supported by a collaborative, fast-paced environment.

Work Setup

primarily onsite Boulder, Colorado; minimal travel (0-10%).