Research Associate

brown; Seattle (WA); On-site; USD 85,000 - 110,000; Full time

Job summary

Brown University’s Department of Molecular Biology, Cell Biology and Biochemistry seeks a Research Associate to manage proteomics projects within the Proteomics Core Facility, coordinating LC-MS/MS analyses and data interpretation for a diverse research community.

The role requires a Master’s degree in biology/biochemistry/analytical chemistry/proteomics/metabolomics and hands‑on mass spectrometry experience; strong organizational, communication, and training skills are essential.

Qualifications

• Master’s degree in biology/biochemistry/analytical chemistry/proteomics/metabolomics with 2–5 years’ related experience.
• Hands-on mass spectrometry and LC/MS workflows including sample prep, data acquisition and analysis.
• Knowledge of proteins, chemistry, and biochemistry with equivalent education/experience.
• Experience with small molecule/metabolite LC/MS workflows is desired.
• Strong software skills for protein MS data analysis (Spectromine/Spectronaut/Proteome Discoverer).
• Proteomics sample prep experience (S-Trap, in-solution digestion, barocycler, on-bead, PreOmics) desirable.

Responsibilities

• Manage research projects from design through closeout within the Proteomics Core Facility.
• Coordinate LC-MS/MS acquisition, QC, data evaluation and client consultations.
• Provide technical oversight and training to undergraduate researchers.
• Maintain and expand analytical services for proteomics and metabolomics analyses.

Skills

Mass spectrometry

LC/MS workflows

Sample preparation

Instrument operation troubleshooting

Data interpretation

Spectromine

Spectronaut

Proteome Discoverer

Protein biochemistry

Education

Master’s degree in biology/biochemistry/analytical chemistry/proteomics/metabolomics

Tools

Spectromine

Spectronaut

Proteome Discoverer

Job description

Job Description:

The Research Associate is a specialized scientific staff member within the Proteomics Core Facility who independently manages assigned research projects from design/project intake through project closeout while supporting mass spectrometry -based proteomics and small molecule/metabolite analyses for a diverse research community. The Research Associate independently performs and coordinates sample preparation, LC-MS/MS acquisition, quality control, evaluates data, manages project status and intake documentation in iLabs, conducts client consultations including project closeouts/follow-up meetings, and provides technical oversight and training to undergraduate researchers. This cross-disciplinary role is essential to maintaining and expanding the Core’s analytical services which requires advanced knowledge of protein biochemistry, analytical chemistry, chromatography, high resolution mass spectrometry, data interpretation, and research project management.

This is a fixed term position with a current end date of one year from the date of hire, which may be extended based upon available funding.

Job Qualifications

Education and Experience (Grade 9):

• Required: Master’s degree in biology, biochemistry, analytical chemistry, proteomics, metabolomics, or a closely related field plus 2-5 years’ related experience.
• Demonstrated hands-on experience with mass spectrometry and LC/MS workflows, including sample preparation, method execution and optimization, LC-MS data acquisition and analysis, instrument operation and troubleshooting, and interpretation of experimental results. Experience providing technical support or guidance to research projects and communicating analytical results to scientific collaborators is also required.
• Knowledge of laboratory approaches and techniques in the areas of Proteins, Chemistry, and Biochemistry required.
• And/or equivalent combination of education and experience.
• Experience with small molecule or metabolite LC/MS analysis is strongly desired. Candidate must understand the distinct sample preparation, chromatographic, and acquisition requirements of peptide/protein vs metabolite workflows.
• Strong computer skills with experience using software for the analysis of protein mass spectrometry data is strongly advantageous, specifically Spectromine, Spectronaut, Proteome Discoverer.
• Experience working with proteins (i.e. Western Blots, BCAs, Purification, performing proteomic sample prep (e.g. Protifi S-Trap, In-solution digestion, Barocycler assisted-digestion, on-bead digestion, PreOmics etc.) is desirable.

Education and Experience (Grade 10):

• Required: Master’s degree in biology, biochemistry, analytical chemistry, proteomics, metabolomics, or a closely related field plus 5-7 years’ related experience.
• Demonstrated hands-on experience with mass spectrometry and LC/MS workflows, including sample preparation, method execution and optimization, LC-MS data acquisition and analysis, instrument operation and troubleshooting, and interpretation of experimental results. Experience providing technical support or guidance to research projects and communicating analytical results to scientific collaborators is also required.
• Knowledge of laboratory approaches and techniques in the areas of Proteins, Chemistry, and Biochemistry required.
• Experience working with proteins (i.e. Western Blots, BCAs, Purification, performing proteomic sample prep (e.g. Protifi S-Trap, In-solution digestion, Barocycler assisted-digestion, on-bead digestion, PreOmics etc.) required.
• And/or equivalent combination of education and experience.
• Experience with small molecule or metabolite LC/MS analysis is strongly desired. Candidate must understand the distinct sample preparation, chromatographic, and acquisition requirements of peptide/protein vs metabolite workflows.
• Strong computer skills with experience using software for the analysis of protein mass spectrometry data is strongly advantageous, specifically Spectromine, Spectronaut, Proteome Discoverer.

Job Competencies

• Availability to receive and process user samples during Core Facility Operation Hours (M-F, 9-5PM)
• Excellent written, verbal, and client-facing communication skills. Ability to be observant and self-motivated.
• Ability to think critically and problem-solve including sample preparation and instrument troubleshooting.
• Ability to work independently.
• Ability to complete accurate records and follow detailed instructions.

CRIMINAL BACKGROUND AND EDUCATION CHECK REQUIRED.

Please review additional information on the Benefits of Working at Brown.

Recruiting Start Date:

2026-09-01

Job Posting Title:

Research Associate

Department:

Department of Molecular Biology, Cell Biology and Biochemistry

Grade:

Grade 9

Worker Type:

Employee

Worker Sub-Type:

Fixed Term (Fixed Term)

Time Type:

Full time

Scheduled Weekly Hours:

37.5

Position Work Location:

Onsite

Submission Guidelines:

The designated Position Work Location for each position determines the approved modality of work. Positions are classified based on the operational and business needs of the department and may be designated as on-site, hybrid, or remote.

Employees with a designated position work location as remote must reside and perform their work in a state where Brown University is registered to do business. Brown University is a registered employer in the following states: Rhode Island, California, Colorado, Connecticut, Florida, Maryland, Massachusetts, New York, New Hampshire, New Jersey, North Carolina, Washington, D.C.

Please note that to be considered for a staff position at Brown University, you must submit a separate application for each position you wish to be considered for. Applications are reviewed only for the specific position to which they are submitted and are not automatically considered for future openings.

This position is not eligible for visa sponsorship.

Still Have Questions?

If you have any questions you may contact [e-mail].

Brown is an E-Verify Employer.

EEO Statement:

Brown University provides equal opportunity and prohibits discrimination, harassment and retaliation based upon a person’s race, color, religion, sex, age, national or ethnic origin, disability, veteran status, sexual orientation, gender identity, gender expression, or any other characteristic protected under applicable law, in the administration of its policies, programs, and activities. The University recognizes and rewards individuals on the basis of qualifications and performance. The University maintains certain affirmative action programs in compliance with applicable law.