Research Assistant II - Neurogenetics Research

Kennedy Krieger Institute; Baltimore (MD); On-site; USD 40,000 - 66,000; Full time

Job summary

Kennedy Krieger Institute is seeking a Research Assistant II to support the PI in studies on neural networks and genetic models of neurodevelopmental disorders. You will read literature, plan and perform experiments, analyze data, and draft manuscripts for publication.

The role requires tissue culture experience, familiarity with R and Python, and basic EEG exposure; MATLAB and image/data analysis skills are a plus, with collaboration across our neuroscience teams.

Qualifications

• Bachelor's degree in a science-related field such as biology, neuroscience, psychology, biomedical engineering, computer science, or physics.
• Two years’ experience with tissue culture or molecular biology is preferred.
• Experience with R and Python is preferred; MATLAB experience is a plus.

Responsibilities

• Assist the PI with scientific studies to understand neural network dysfunction in genetic models of neurodevelopmental disorders.
• Read literature, carry out experiments, analyze data, and draft manuscripts.
• Present findings to the team and collaborators.
• Perform tissue culture experiments using iPSC-derived neural cells and conduct supporting in vivo work under approved protocols.

Skills

Tissue culture

R

Python

EEG

MATLAB

Education

Bachelor's degree

Tools

GraphPad Prism

Job description

The Research Assistant II assists the PI with scientific studies to elucidate the cellular mechanisms of neural network dysfunction in genetic models of neurodevelopmental disorders. The Research Assistant is able to read and understand scientific literature, carry out experiments, work collaboratively, plan experiments, analyze data, draft the manuscript and make presentations to others about the work.

Responsibilities

• Perform tissue culture experiments using iPSC derived neural cells.
• Use methods such as fluorescent in situ hybridization, immunohistochemistry, Ca2+ imaging, and MEA recording.
• Conduct experiments in rodents, using surgical techniques, post-operative care, behavioral studies and euthanasia, in accordance with IACUC-approved protocols and the Guide for the Care and Use of Experimental Animals.
• Manage the colony of transgenic mice, obtaining samples for genotyping, maintaining accurate records of genotypes and breeding, and managing supply of breeders and mice required for experiments.
• Use computerized microscopy and image analysis systems to collect experimental data; analyze data with statistics packages such as R and GraphPad Prism.
• Design and plan experiments, in coordination with the PI, using above/other methods.
• Work cooperatively with others in the laboratory to carry out collaborative research.

Qualifications

• Ideal candidate would have tissue culture experience, R, or Phyton, and some exposure to EEG.
• Experience in MATLAB, R and Phyton is preferred.
• Training in animal surgical techniques, EEG placement and post-operative care is preferred.

Education

• Bachelor’s degree required, preferably in a science related field such as biology, neuroscience, psychology, biomedical engineering, computer science, or physics.

Experience

• Previous laboratory training and experience in any field of science is required.
• Two years’ experience with tissue culture, molecular biology, is preferred.

USD $40,043.12/Yr.

USD $66,204.53/Yr.