Research Assistant, Applications Lab

PacBio; Menlo Park (CA); On-site; USD 55,000 - 83,000; Full time

Job summary

PacBio is seeking a Research Assistant to support laboratory operations, including DNA and RNA library preparation, sequencing on PacBio HiFi systems, and troubleshooting experiments. You will work closely with scientists to ensure reliable execution of workflows, maintain accurate records, and deliver high-quality sequencing results.

This hands-on role requires attention to detail, strong organization, and an interest in genomics technologies.

Qualifications

• Hands-on molecular biology techniques with DNA/RNA sample prep.
• Ability to follow detailed laboratory protocols and maintain accurate records.
• Strong attention to detail, organizational skills, and ability to manage multiple experiments.

Responsibilities

• Sequencer operations: Load, operate, and monitor PacBio sequencing systems; track run performance.
• Library preparation: Prepare DNA and RNA sequencing libraries with QC procedures.
• Troubleshooting: Investigate issues and implement corrective actions with scientific teams.
• Laboratory operations: Maintain records, organize samples and reagents, assist with equipment maintenance.

Education

Bachelor’s degree in molecular biology, genetics, biochemistry, or related life sciences

Job description

OPPORTUNITY

PacBio is advancing highly accurate long-read sequencing to enable new discoveries and applications in genomics research and genetic testing. Our Applications Lab plays an important role in demonstrating the capabilities of PacBio technology, supporting customer projects, and developing new sequencing workflows.

We are seeking a Research Assistant to support laboratory operations, including DNA and RNA library preparation, sequencing on the PacBio HiFi systems, and troubleshooting experiments.

ABOUT THE ROLE

As a Research Assistant in PacBio’s Applications Lab, you will support sequencing projects for internal teams and external customers. You will operate and monitor sequencing systems and help ensure reliable execution of laboratory workflows.

You will work closely with scientists and other laboratory staff to troubleshoot experiments, maintain accurate records, and deliver high-quality sequencing results. This is a hands‑on laboratory role requiring attention to detail, strong organizational skills, and an interest in genomics technologies.

RESPONSIBILITIES

• Sequencer operations: Load, operate, and monitor PacBio sequencing systems. Track run performance, identify issues, and support reliable completion of sequencing experiments.
• Library preparation: Prepare DNA and RNA sequencing libraries, including whole-genome sequencing (WGS) and RNA workflows, following established protocols and quality control procedures.
• Troubleshooting: Identify and investigate issues with library preparation and sequencing runs. Work with laboratory scientists and technical teams to determine causes and implement corrective actions.
• Laboratory operations: Maintain accurate experimental records, organize samples and reagents, and support routine laboratory equipment maintenance and inventory management.

QUALIFICATIONS

Required

• Bachelor’s degree in molecular biology, genetics, biochemistry, or a related life sciences field, or equivalent laboratory experience.
• Hands‑on laboratory experience with molecular biology techniques, including DNA or RNA sample preparation.
• Ability to follow detailed laboratory protocols, maintain accurate records, and consistently deliver high-quality results.
• Strong attention to detail, organizational skills, and ability to manage multiple experiments and priorities.
• Good analytical and troubleshooting skills, with the ability to recognize experimental issues and work collaboratively to resolve them.
• Strong communication and teamwork skills.

Preferred Experience

• Experience with next‑generation sequencing, including sequencing library preparation or instrument operation.
• Familiarity with DNA and RNA quality control methods and laboratory automation.
• Experience working in a genomics core facility, sequencing service laboratory, or other high‑throughput laboratory environment.

Candidates must have current authorization to work in the United States without the need for present or future sponsorship.

Non‑Field Based Employees are required to be onsite Monday‑Thursday (Friday work from home). Depending on the role, some employees may be required to be 100% onsite.

You may be required from time to time to visit and work at PacBio locations and for such times as the Company considers necessary for the proper performance of your duties.

All listed tasks and responsibilities are deemed as essential functions to this position; however, business conditions may require reasonable accommodations for additional tasks and responsibilities.

All qualified applicants will receive consideration for employment without regard to race, sex, color, religion, national origin, protected veteran status, or on the basis of disability, gender identity, and sexual orientation.

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Salary Range:

$55,300.00 - $82,900.00

If you are an individual with a disability and require a reasonable accommodation to complete any part of the application process, or are limited in the ability or unable to access or use this online application process and need an alternative method for applying, you may contact us at 650‑521‑8000, or [e-mail] for assistance.

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All qualified applicants will receive consideration for employment without regard to race, sex, color, religion, national origin, protected veteran status, or on the basis of disability, gender identity, and sexual orientation.