Remote Senior Director, DMPK & Translational Pharmacology

BioAge; Northern (KY); Hybrid; USD 230,000 - 290,000; Full time

Benefits offered by this job

Remote work

Health and wellness benefits

401(k) with match

Paid time off

Job summary

BioAge Labs is seeking an experienced Director, DMPK (or Senior Director) to lead DMPK and translational pharmacology across the portfolio. This fully remote role welcomes candidates from any continental US state, reporting to the VP of Non Clinical Development.

You will drive ADME, PK/PD modeling, and dose selection for IND-enabling programs. Responsibilities include partnering across disciplines, guiding regulatory submissions, and mentoring scientists while advancing BioAge's mission in aging

Qualifications

• PhD in Pharmacokinetics, Pharmaceutical Sciences, Pharmacology, Drug Metabolism, or related field.
• 12+ years in biotech/pharma with small molecule development experience.
• Led DMPK strategy across multiple programs and IND-enabling work.
• Experience supporting regulatory submissions (INDs/CTAs).
• Experience coordinating with external CROs and collaborators.
• Proven leadership in cross-functional teams.

Responsibilities

• Lead DMPK and translational pharmacology across BioAge pipelines from lead optimization to IND-enabling studies.
• Develop ADME, PK/PD, and dose selection strategies; optimize human dose prediction.
• Design and oversee in vitro/in vivo DMPK, metabolite ID, and bioanalytical studies.
• Partner with chemistry, biology, toxicology, and clinical pharmacology to guide programs.
• Direct quantitative PK/PD and PBPK modeling to inform decisions.
• Mentor scientific staff and build decision-making frameworks for translational science.

Skills

DMPK

ADME

PK/PD

Regulatory submissions

CRO management

Team leadership

Pharmacology

Bioanalysis

Data interpretation

Regulatory strategy

Education

PhD in Pharmacokinetics/Pharmaceutical Sciences

Tools

PBPK modeling

Population PK

Job description

BioAge Labs is seeking an experienced Director, DMPK (or Senior Director) to lead DMPK and translational pharmacology across the portfolio. This fully remote role welcomes candidates from any continental US state, reporting to the VP of Non Clinical Development.

You will drive ADME, PK/PD modeling, and dose selection for IND-enabling programs. Responsibilities include partnering across disciplines, guiding regulatory submissions, and mentoring scientists while advancing BioAge's mission in aging