Remote Senior Clinical Trial Manager: Quality & Compliance Lead

Ladders; United States; Remote; USD 168,000 - 188,000; Full time

Benefits offered by this job

Remote work flexibility

Occasional travel to Boston

Continuous improvement initiatives

Dynamic cross-functional teamwork

Industry-leading collaboration

Job summary

Ladders is seeking a Senior Clinical Trial Manager to lead end-to-end trial delivery in the Pharmaceuticals & Biotech space. This remote role includes occasional travel to Boston and a strong emphasis on GCP compliance, TMF quality, and regulatory readiness.

You will partner with internal and external stakeholders, manage trial trackers and budgets, and drive continuous improvement across clinical development.

Qualifications

• 5+ years managing clinical trials in Sponsor or CRO environments.
• Deep understanding of clinical trial operations and international regulations.
• Proven experience leading clinical operations teams.
• Ability to collaborate across diverse functional areas.

Responsibilities

• Manage clinical trials from protocol concept to study report in compliance with GCP and regulations.
• Engage strategically with key stakeholders.
• Oversee trial trackers for regulatory documents and study budget.
• Contribute to IRB/EC and regulatory submissions.
• Ensure TMF completeness and inspection readiness.
• Review documentation for quality requirements.
• Identify study risks and implement mitigation strategies.

Skills

Trial management experience

Regulatory knowledge

Leadership

Cross-functional collaboration

Education

Bachelor's degree in a scientific field

Advanced degree preferred

Job description

Ladders is seeking a Senior Clinical Trial Manager to lead end-to-end trial delivery in the Pharmaceuticals & Biotech space. This remote role includes occasional travel to Boston and a strong emphasis on GCP compliance, TMF quality, and regulatory readiness.

You will partner with internal and external stakeholders, manage trial trackers and budgets, and drive continuous improvement across clinical development.