Remote-Ready Accounting Manager | GAAP & Payroll Lead

assemblybioinc; South San Francisco (CA); Hybrid; USD 123,000 - 132,000; Full time

Job summary

Assembly Bio in South San Francisco, CA is seeking an experienced Accounting Manager to oversee day-to-day accounting, ensure GAAP compliance, and strengthen SOX controls. This hands-on role requires payroll expertise and collaboration with finance teams.

You will manage general ledger functions, multi-state payroll in Paylocity, vendor payments, expense reimbursements, and audits. The position offers hybrid work with periodic on-site presence in South San Francisco and growth opportunities in a

Qualifications

• Bachelor’s degree in Accounting or Finance.
• 5+ years of relevant accounting experience with multi-state payroll.
• Proficient payroll processing, tax filings, and reporting.
• Strong ability to prepare and reconcile complex accounts.
• Experience with fraud indicators in vendor setup and payment.

Responsibilities

• Manage general ledger accounting functions, including allocations, payroll accounting, fixed assets, accounts payable, accruals and cash.
• Preparing and booking journal entries with a strong understanding of the underlying accounting logic and supporting documentation.
• Owning multi-state payroll accounting and processing in Paylocity, including tax setup and compliance across jurisdictions, payroll journal entries, reconciliations, and troubleshooting.
• Serving as the primary preparer for weekly vendor changes and vendor payment runs, applying strong fraud-prevention judgment to detect and elevate suspicious changes.
• Managing the employee expense reimbursement program, including administration of the expense reporting system, policy compliance reviews, employee support, and related reconciliations.
• Coordinating Finance-related onboarding and offboarding activities, including system access provisioning, user maintenance, and training for Finance applications and processes.
• Preparing quarterly government census/statistical filings accurately and on time.
• Helping with the 401K, quarterly and year-end financial audit activities.
• Monitoring and analyzing financing accounting data.
• Performing ad hoc analysis and projects as requested.
• Be a trusted business partner and advisor to various stakeholders within Finance and Accounting and across the Company.
• Proactively liaise with external auditors to drive timely closure of PBC requests and auditor inquiries.

Skills

Payroll processing

GAAP knowledge

Financial analysis

Internal controls

Education

Bachelor's degree in Accounting or Finance

Tools

Oracle Fusion

Paylocity

Fidelity

Concur

Excel

PowerPoint

Job description

Assembly Bio in South San Francisco, CA is seeking an experienced Accounting Manager to oversee day-to-day accounting, ensure GAAP compliance, and strengthen SOX controls. This hands-on role requires payroll expertise and collaboration with finance teams.

You will manage general ledger functions, multi-state payroll in Paylocity, vendor payments, expense reimbursements, and audits. The position offers hybrid work with periodic on-site presence in South San Francisco and growth opportunities in a