Remote Global Clinical Trial Manager II

Syneos Health, Inc.; United States; Remote; USD 120,000 - 180,000; Full time

Job summary

Syneos Health is seeking a Single Sponsor Global Clinical Trial Manager II with a solid CRA background. This fully home-based role is open to candidates in the UK, Poland, Spain and Bulgaria, with remote work in Spain also noted.

The position emphasizes site management, monitoring, data integrity and risk-based approaches across international sites. The role involves leadership of cross-functional teams, management of study budgets, and collaboration with investigators.

Qualifications

• Bachelor’s degree or RN in a related field or equivalent combination of education, training and experience.
• Demonstrated ability to lead and align teams in the achievement of project milestones.
• Demonstrated capability of working in an international environment.
• Demonstrated expertise in site management and monitoring (clinical or central).
• Preferred experience with risk-based monitoring.
• Demonstrates understanding of clinical trial management financial principles and budget management.
• Knowledge of Good Clinical Practice/ICH Guidelines and other applicable regulatory requirements.
• Must demonstrate good computer skills.
• Good communication, presentation and interpersonal skills among project team and with sites.
• Strong conflict resolution skills.
• Demonstrated ability to apply problem solving techniques to resolve complex issues, and apply a risk management approach to identifying and mitigating potential threats to the successful conduct of a clinical research project.
• Demonstrates critical thinking to determine the cause and appropriate solution in the identification of issues.
• Moderate travel may be required, approximately 20%.

Responsibilities

• Responsible for site management oversight, clinical monitoring and central monitoring deliverables with a focus on patient safety, protocol/GCP/regulatory compliance and data integrity.
• Oversees site interactions post activation through site closeout with activities like patient recruitment or investigator payments.
• May identify critical data and process risks and mitigation related to RA CT.
• Reviews study scope, budget and protocol content ensuring the team is aware of obligations.
• Uses data, metrics and reports to identify risks to deliverables.
• Escalates risks to project manager when scope or timelines are at risk.
• Proposes risk mitigations and strategic solutions.
• Participates in key meetings such as Kick Off Meeting.
• Interacts with investigators and site staff as needed for escalation or alignment.
• Coordinates training on protocol specifics, CRF completion, dashboards and SOPs.
• Oversees staffing and resource allocations for CRAs and Central Monitors.
• Ensures quality of deliverables and visibility through CTMS and tracking tools.
• Reviews monitoring dashboards to ensure timely execution of visits and data updates.
• Supports risk assessment planning and CMP/SMP compliance.
• Provides feedback to line managers on team performance.
• May support larger, more complex trials.

Skills

Leadership

International teamwork

Site monitoring

Risk-based monitoring

Budget management

GCP/ICH knowledge

Communication skills

Problem solving

Critical thinking

Travel willingness

Education

Bachelor’s degree or RN

Tools

CTMS

EDC

Job description

Syneos Health is seeking a Single Sponsor Global Clinical Trial Manager II with a solid CRA background. This fully home-based role is open to candidates in the UK, Poland, Spain and Bulgaria, with remote work in Spain also noted.

The position emphasizes site management, monitoring, data integrity and risk-based approaches across international sites. The role involves leadership of cross-functional teams, management of study budgets, and collaboration with investigators.