Remote Discovery Biologist for Radioligand Therapy
Clora
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Descripción de la vacante
Clora is partnering with a biotech to discover and develop radioligand therapy candidates for solid tumors. This remote, consulting role focuses on advancing tumor-targeting biodistribution and retention while minimizing normal tissue exposure.
You will lead in vitro and in vivo studies, work with radiochemistry teams, and guide IND-enabling pharmacology studies. The ideal candidate has a PhD or MS in cancer biology or related field with 5+ years in biotech/pharma, and strong expertise in
Formación
- PhD or MS in cancer biology, pharmacology, molecular biology, or related field with at least 5+ industry experience
- Strong background in antibody biology, tumor models, and preclinical oncology pharmacology
- Experience with radiopharmaceuticals, quantitative biodistribution, SPECT/PET imaging, or radio-labeled biologics is strongly preferred
Responsabilidades
- Design and oversee in vitro and in vivo studies evaluating RLT candidate binding, internalization, tumor uptake, and retention.
- Characterize the impact of antibody affinity, binding kinetics, and Fc engineering on tumor targeting and systemic clearance.
- Analyze biodistribution, imaging, and tissue radioactivity data to support lead optimization and candidate selection.
- Coordinate radiolabeling, imaging, and pharmacology studies with external CROs and radiochemistry collaborators.
- Support selection of development candidates and design of IND-enabling pharmacology studies
Conocimientos
Educación
Descripción del empleo
Clora is partnering with a biotech to discover and develop radioligand therapy candidates for solid tumors. This remote, consulting role focuses on advancing tumor-targeting biodistribution and retention while minimizing normal tissue exposure.
You will lead in vitro and in vivo studies, work with radiochemistry teams, and guide IND-enabling pharmacology studies. The ideal candidate has a PhD or MS in cancer biology or related field with 5+ years in biotech/pharma, and strong expertise in
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