Remote Computational Biologist, Cancer Diagnostics Multiomics

Freenome; Brisbane (CA); Remote; USD 131,000 - 190,000; Full time

Benefits offered by this job

Equity

Cash bonuses

Medical benefits

Job summary

Freenome is seeking a Computational Biologist, Assay Development to join our CBAD team. You will apply your expertise to develop early, noninvasive cancer tests and collaborate across Regulatory, Quality, Molecular Research, Biostatistics, Computational Science, and Engineering.

The role can be hybrid or fully remote and reports to the Director of Computational Biology. You will design and execute development experiments for multiomics cancer screening tests, develop regulated strategies toward

Qualifications

• Post-graduate degree in statistics, computational biology, bioinformatics, cancer biology, or related quantitative field.
• 2-3+ years of industry experience (for Sr. Scientist level)
• Experience in experimental design and analysis of high-throughput, quantitative technologies in genomics, epigenomics, transcriptomics, or proteomics (e.g. target capture with UMI, Hi-C, ATAC-seq, RNA-seq, bisulfite sequencing, microarrays, mass spec, immunoassays).
• Familiarity with and ability to select and leverage bioinformatics tools for the above molecular assays.
• Experience in applied statistics, such as in hypothesis testing, regression techniques, and appropriate use of simulation.
• Expertise in data analysis and visualization using R (tidyverse), or Python statistical packages (Numpy, Matplotlib, Pandas), or equivalent, under version control.
• Excellent oral and written communication skills to communicate to scientific and broader audiences, with keen attention to detail.
• Ability to work on a cross-functional team in our highly collaborative environment, working with both computational and experimental scientists.

Responsibilities

• <li>Plan and execute development experiments for Freenome’s multiomics cancer screening tests.</li>
• <li>Partner cross-functionally with computational, development, regulatory, and quality leaders to develop and execute a regulated development strategy working toward FDA approval.</li>
• <li>Use quantitative skills to develop computational methods and interpret complex experimental results to optimize and validate technology for sample collection, preparation, and detection.</li>
• <li>Develop and execute experimental design and analysis plans for Development, Verification, and Validation studies, closely partnering with Biostatistics, Development, and Pre-Analytics teams.</li>
• <li>Work closely with molecular and computational research teams developing Freenome’s IVD products for blood-based molecular assays including cfDNA, proteins, and biomarkers.</li>
• <li>Impact patient lives through the development and launch of high quality cancer screening technologies</li>

Skills

Statistics

Bioinformatics

Computational Biology

Data Analysis

R (tidyverse)

Python (NumPy, Matplotlib, Pandas)

Communication skills

Cross-functional teamwork

Education

Master's or PhD in statistics, computational biology, bioinformatics, cancer biology, or related quantitative field

Tools

UMI target capture

Hi-C

ATAC-seq

RNA-seq

Bisulfite sequencing

Microarrays

Mass spectrometry

Immunoassays

Version control

Job description

Freenome is seeking a Computational Biologist, Assay Development to join our CBAD team. You will apply your expertise to develop early, noninvasive cancer tests and collaborate across Regulatory, Quality, Molecular Research, Biostatistics, Computational Science, and Engineering.

The role can be hybrid or fully remote and reports to the Director of Computational Biology. You will design and execute development experiments for multiomics cancer screening tests, develop regulated strategies toward