Remote Associate Director, Clinical Operations - Trial Lead

Centessa Pharmaceuticals; Boston (MA); Remote; USD 103,000 - 152,000; Full time

Benefits offered by this job

Medical plans (PPO/EPO) and dental/vis

401(k) and wellness programs

Travel opportunities

Job summary

Centessa Pharmaceuticals is seeking an experienced Associate Director, Clinical Operations for a remote US-based contract-to-hire role. Lead end-to-end trial operations across Orexin programs, partnering with Regulatory, Data Management, and Safety to meet timelines and budgets.

The role requires 8+ years in pharma/biotech/CRO, multi-phase trial experience, and strong vendor management. Travel flexibility and regulatory exposure are a plus.

Qualifications

• Bachelor’s degree in sciences; advanced degree preferred.
• 8+ years of pharma/biotech/CRO experience.
• Experience leading multi-phase (1–3) trials, domestic & international.

Responsibilities

• Lead end-to-end clinical trial ops from start-up to close-out.
• Develop operational plans, timelines, and KPIs for studies.
• Collaborate with CD, Regulatory, Data Management, Biostatistics, and Safety.
• Prepare and review study documents (protocols, ICFs, monitoring plans).
• Manage budgets and ensure delivery within financial parameters.
• Provide status updates on risks and milestones to leadership.
• Identify risks and implement mitigation to maintain timelines and quality.
• Support contracts, clinical trial agreements, and budgets.
• Contribute to regulatory strategy and FDA submissions prep.
• Oversee CROs, vendors, and external partners; ensure performance.

Skills

Leadership

Cross-functional collaboration

Budget management

Communication

Project management

Organizational skills

Problem-solving

Proactive

Education

Bachelor’s degree in sciences

Advanced degree preferred

Tools

CTMS

Job description

Centessa Pharmaceuticals is seeking an experienced Associate Director, Clinical Operations for a remote US-based contract-to-hire role. Lead end-to-end trial operations across Orexin programs, partnering with Regulatory, Data Management, and Safety to meet timelines and budgets.

The role requires 8+ years in pharma/biotech/CRO, multi-phase trial experience, and strong vendor management. Travel flexibility and regulatory exposure are a plus.