QC Associate II — Data-Driven Lab Quality & NGS

Twistbioscience; Portland (OR); On-site; USD 70,000 - 95,000; Full time

Job summary

Twist Bioscience is seeking a QC Associate II to implement and continually improve QC methods in a high‑throughput production lab. You will work with the operations team to monitor quality of Twist DNA products using NGS sequencing, qPCR, fragment analysis, and other metrics.

The role requires data‑driven decisions, strong documentation, and collaboration for ISO/GDP compliant processes. You will report to the QC manager and contribute to continuous improvement in a fast-paced environment.

Qualifications

• BS/MS in Biochemistry, Chemistry, Molecular Biology or related field
• 2+ years industrial experience in Operations/QC
• Knowledge of/experience with Quality Control and Quality Assurance principles, including GMP/ISO
• Knowledge of molecular biology techniques such as PCR, Cloning & Sequencing
• Knowledge of analytical techniques such as spectroscopy, gel electrophoresis, etc.
• Experience with automated robotic systems and LIMS systems
• Proven ability to troubleshoot complex problems
• Excellent verbal and written communication skills

Responsibilities

• Independently perform QC release for standard product families to ensure 100% compliance with customer specifications.
• Execute and troubleshoot routine QC assays (NGS, qPCR, fragment analysis, NanoDrop/Qubit); identify and elevate atypical results.
• Initiate Nonconformances and other Quality Events for OOS, OOT, and atypical results, and follow up on progress and action items.
• Support impact assessments and investigations; contribute to root cause analysis using 5-Why, Fishbone, and DMAIC techniques.
• Review CAPAs and process deviations from a QC perspective.
• Monitor QC data and assist in preparation of product and process quality reports, including trend analysis.
• Author and review product quality documentation (SOPs, test methods, work instructions, labels).
• Maintain QC batch records, calibration records, and inventory under ISO and GDP requirements.
• Identify and support continuous improvement initiatives in the QC laboratory.

Skills

Quality Control

Data-driven decisions

QC documentation

Communication

Education

Biochemistry/Chemistry/Molecular Biology degree

Tools

LIMS systems

Robotics systems

Job description

Twist Bioscience is seeking a QC Associate II to implement and continually improve QC methods in a high‑throughput production lab. You will work with the operations team to monitor quality of Twist DNA products using NGS sequencing, qPCR, fragment analysis, and other metrics.

The role requires data‑driven decisions, strong documentation, and collaboration for ISO/GDP compliant processes. You will report to the QC manager and contribute to continuous improvement in a fast-paced environment.