Proteome Editor Design Lead - AI BioDesign Scientist

ClearCompany Talent Management Software; Seattle (WA); On-site; USD 128,000 - 160,000; Full time

Benefits offered by this job

Relocation assistance

Visa sponsorship

Job summary

The Allen Institute seeks a Scientist III to lead the Proteome Editor Design flywheel, driving design‑test‑learn cycles and active‑learning integration with ML teammates. You will steer cellular library screening workflows and collaborate across teams to deliver model‑ready datasets and impactful results.

Applicants should have a PhD in biochemistry or related field with 5+ years post‑doc experience, and willingness to work onsite in Seattle, WA. Relocation and visa sponsorship may be available.

Qualifications

• PhD required in biochemistry, molecular biology, or related field.
• Minimum 5 years of post‑doctoral experience.
• Experience with functional genomics, massively parallel reporter assays, multiplexed assays of variant effect, saturation mutagenesis, or plasmid library‑based screening.
• Experience architecting cellular library screening workflows (e.g., MPRAs or other high‑throughput cell‑based discovery platforms).
• Proven ability to lead scientific projects and collaborate cross‑functionally with computational/ML teammates.

Responsibilities

• Lead the Proteome Editor team to build and run a rapid, repeatable design–test–learn pipeline focused on proteome editor screening.
• Design and oversee library screening and degrader evaluation experiments to generate high‑quality, model‑ready datasets.
• Partner with machine learning colleagues to define next targets, curate data, and implement active‑learning strategies.
• Optimize flywheel performance by improving turnaround time, throughput, cost, and per‑cycle model lift.
• Coordinate with other flywheel leads and AI Biodesign stakeholders to align priorities, timelines, and dependencies.
• Mentor and manage a high‑performing team with clear communication and emotional intelligence.
• Present scientific results internally and at conferences and in publications.

Education

PhD in biochemistry, molecular biology, or related field

Strong leadership and cross-functional collaboration

Job description

The Allen Institute seeks a Scientist III to lead the Proteome Editor Design flywheel, driving design‑test‑learn cycles and active‑learning integration with ML teammates. You will steer cellular library screening workflows and collaborate across teams to deliver model‑ready datasets and impactful results.

Applicants should have a PhD in biochemistry or related field with 5+ years post‑doc experience, and willingness to work onsite in Seattle, WA. Relocation and visa sponsorship may be available.