Protein Expression Scientist I: Purification & Baculovirus

BioSpace; Brisbane (CA); On-site; USD 125,000 - 151,000; Full time

Benefits offered by this job

Bonus

Equity

Onsite position

Job summary

Nurix Therapeutics, Inc. is seeking a detail-oriented Scientist I for Protein Purification & Expression to join the DEL and Protein Sciences team.

This role plans, coordinates, and executes expression of recombinant proteins in baculovirus and mammalian cell systems, and documents conditions and results in internal databases and ELNs. You will maintain insect and mammalian cell cultures, perform protein purification and characterization, and work cross-functionally in a fast-paced environment.

Qualifications

• Ph.D. or equivalent with 2+ years of relevant experience.
• This position requires 2+ years of experience working with insect cell lines and baculovirus expression of recombinant proteins.
• Additional experience with mammalian expression (e.g. HEK293) is a plus.
• Industry experience preferred with ability to overexpress milligram amounts of protein for multiple protein classes.
• Must be able to lift 50+ pounds.

Responsibilities

• Maintain insect cell and mammalian cell cultures.
• Perform baculovirus-based expression and purification of recombinant proteins (clone design, bacmid purification, MOI studies, cell culture, biomass harvest).
• Characterize proteins by SDS-PAGE, chromatography, and thermal stability methods.
• Document expression conditions and results in internal databases and ELNs.

Skills

Insect cell culture

Baculovirus expression

Protein purification

Education

PhD or equivalent

Tools

SDS-PAGE

Size-exclusion chromatography

nanoDSF

Job description

Nurix Therapeutics, Inc. is seeking a detail-oriented Scientist I for Protein Purification & Expression to join the DEL and Protein Sciences team.

This role plans, coordinates, and executes expression of recombinant proteins in baculovirus and mammalian cell systems, and documents conditions and results in internal databases and ELNs. You will maintain insect and mammalian cell cultures, perform protein purification and characterization, and work cross-functionally in a fast-paced environment.