Protein Biochemist - Lead Discovery & Characterization

Initial Therapeutics, Inc.

Indianapolis (IN)

On-site

USD 81,000 - 149,000

Full time

9 days ago
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Job summary

Lilly's BioTDR organization in Indianapolis seeks an Associate/Senior Associate Scientist to join the Lead Optimization Team. You will generate, characterize, and optimize biotherapeutics from lead generation through preclinical development, collaborating with cross-functional teams to address protein reagent properties and advance candidates.

The role emphasizes protein expression, purification, and characterization using Biacore, HPLC, and other biophysical methods, with opportunities to

Qualifications

  • BS or MS in biochemistry or related STEM with 2+ years (MS) or 4+ years (BS) of expression/characterization experience

Responsibilities

  • Express, purify (ÄKTA), and characterize proteins and antibodies using biochemical/biophysical techniques to address physicochemical properties
  • Perform analytical characterization of purified proteins and antibodies
  • Characterize protein structure, stability, and other quality attributes using biochemical/biophysical methods
  • Characterize protein–protein interactions
  • Collaborate with multifunctional teams and present data at team meetings
  • Independently design experiments, generate data, interpret results, and document work
  • Communicate clearly in written and spoken form with good self-management

Skills

Protein design
Protein expression
Chromatography (ÄKTA)
Biochemical analyses

Education

BS/MS in biochemistry/related STEM

Tools

ÄKTA systems
HPLC
Biacore
SEC / aSEC

Job description

Lilly's BioTDR organization in Indianapolis seeks an Associate/Senior Associate Scientist to join the Lead Optimization Team. You will generate, characterize, and optimize biotherapeutics from lead generation through preclinical development, collaborating with cross-functional teams to address protein reagent properties and advance candidates.

The role emphasizes protein expression, purification, and characterization using Biacore, HPLC, and other biophysical methods, with opportunities to

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