Process Engineer - Lilly Medicine Foundry

Initial Therapeutics, Inc.; Lebanon (IN); On-site; USD 64,000 - 168,000; Full time

Job summary

An innovative company is seeking a Process Engineer to join their new advanced manufacturing facility in Lebanon, Indiana. This role focuses on peptide and oligonucleotide synthesis, where you'll tackle technical challenges in equipment design and process optimization. As part of a pioneering startup team, you will help shape the future of drug development by ensuring compliance with quality standards and enhancing manufacturing processes. Join a mission-driven organization dedicated to improving lives through groundbreaking medicines and community support. This is a unique opportunity to make a significant impact in a dynamic and collaborative environment.

Benefits

401(k) Plan

Pension Plan

Medical Benefits

Dental Benefits

Vision Benefits

Flexible Spending Accounts

Life Insurance

Vacation Benefits

Employee Assistance Program

Fitness Benefits

Qualifications

• 1-4 years of experience in a pilot plant or pharmaceutical environment.
• Experience with process engineering of drug substance manufacturing.

Responsibilities

• Provide technical assessment and support for production operations.
• Perform risk assessments for peptide and oligo synthesizers.

Skills

Chemical Engineering

Process Optimization

Analytical Skills

Problem-Solving Skills

Communication Skills

Education

BS in Chemical Engineering

MS in Chemical Engineering

Tools

DeltaV

Dynochem

Aspen

Electronic Lab Notebooks

Job description

At Lilly, we unite caring with discovery to make life better for people around the world. We are a global healthcare leader headquartered in Indianapolis, Indiana. Our employees around the world work to discover and bring life-changing medicines to those who need them, improve the understanding and management of disease, and give back to our communities through philanthropy and volunteerism. We give our best effort to our work, and we put people first. We’re looking for people who are determined to make life better for people around the world.

Overview:

At Lilly, we serve an extraordinary purpose. We make a difference for people around the globe by discovering, developing and delivering medicines that help them live longer, healthier, more active lives. Not only do we deliver breakthrough medications, but you also can count on us to develop creative solutions to support communities through philanthropy and volunteerism.

About The Lilly Medicine Foundry:

Lilly recently announced a$4.5 billion investment to create the Lilly Medicine Foundry, a new center for advanced manufacturing and drug development. The first-ever facility of its kind, combining research and manufacturing in a single location, the Medicine Foundry will allow Lilly to further develop innovative solutions to optimize manufacturing processes and increase capacity for clinical trial medicines, while also reducing costs and environmental impact.

Organizational Overview:

Lilly is currently constructing an advanced research facility for production of API molecules for clinical trials located in Lebanon, IN. This facility is Lilly’s largest investment in a clinical trial manufacturing capacity and is intended to provide APIs for current and future products, including new modalities. This is a unique opportunity to be a part of the startup team for a greenfield manufacturing site, and the successful candidate will help to build the processes and facility to enable a successful startup into GMP manufacturing operations.

We are seeking a Process Engineer to support the pilot plant facility in Lebanon with a focus on peptide and oligonucleotide synthesis. This position involves solving technical challenges with equipment design, developing and sustaining process knowledge, optimizing processes, and managing equipment capabilities.

Responsibilities

The Process Engineer provides technical assessment and support for production operations in the areas of developing and sustaining process knowledge, process and equipment support, process optimization, equipment capability and asset management, and engineering business systems. This role is to serve as a process engineer supporting drug substance active pharmaceutical ingredient (API) manufacturing for peptide and oligonucleotide synthesis.

• Perform impact and risk assessments for the peptide and oligo synthesizers and unit operations

• Learn the lab and plant design for the reactors including automation recipes and procedures.

• Ensure that people and their environment are safe and that company policies concerning safety are followed.

• Ensure processing equipment remains compliant with internal Quality System requirements, applicable engineering standards, and cGMP requirements.

• Assesses rig fit by receiving the technical data package for new processes and performing modeling, simulations and/or experimental work as required to ensure heat and mass transfer are acceptable when scaling to the plant.

• Active engagement and communication with: HSE, Quality Assurance, Tech Services, Development, Operations, FUME/C&Q, Automation, Maintenance, Environmental Monitoring, and Manufacturing.

• Author, review, or approve high-quality technical reports and regulatory submissions dealing with the work performed by the department. Ensure that records and technical notebooks are adequately maintained.

• Demonstrate engagement and employ a quality mindset in all endeavors by proactively identifying quality issues and communicating appropriately.

• Develop or review plans and timetables for project work.

Basic Requirements:

• BS or MS in chemical engineering or related discipline and 1-4 years of experience with a pilot plant, pharmaceutical, biotech, or CMO environment supporting the process engineering of drug substance active pharmaceutical ingredient (API) manufacturing.

Additional Skills/Preferences:

• Deep technical interest and understanding in the field of Chemical Engineering

• Ability to work well in a team environment incorporating a variety of functional relationships and desire to be point of accountability

• Experience with any of the following software packages: DeltaV, Dynochem, Aspen, and/or electronic lab notebooks

• Strong analytical and problem-solving skills

• Strong oral and written communication skills for a diverse audience, e.g., both operations staff and management.

• Ability to work on own initiative and as part of a Process Team consisting of a diverse group of management, production, science and engineering professionals

• Understanding of process control systems

• Creativity to identify improvement opportunities and the tenacity/initiative to see them implemented

• Guidance/mentoring of others through processes

• Flexibility to meet business needs

Other Information:

• Initial location at Lilly Technology Center, Indianapolis.
• Permanent location at the new Lilly Medicines Foundry in Lebanon, Indiana.

Lilly is dedicated to helping individuals with disabilities to actively engage in the workforce, ensuring equal opportunities when vying for positions. If you require accommodation to submit a resume for a position at Lilly, please complete the accommodation request form (https://careers.lilly.com/us/en/workplace-accommodation) for further assistance. Please note this is for individuals to request an accommodation as part of the application process and any other correspondence will not receive a response.

Lilly is proud to be an EEO Employer and does not discriminate on the basis of age, race, color, religion, gender identity, sex, gender expression, sexual orientation, genetic information, ancestry, national origin, protected veteran status, disability, or any other legally protected status.

Our employee resource groups (ERGs) offer strong support networks for their members and are open to all employees. Our current groups include: Africa, Middle East, Central Asia Network, Black Employees at Lilly, Chinese Culture Network, Japanese International Leadership Network (JILN), Lilly India Network, Organization of Latinx at Lilly (OLA), PRIDE (LGBTQ+ Allies), Veterans Leadership Network (VLN), Women’s Initiative for Leading at Lilly (WILL), enAble (for people with disabilities). Learn more about all of our groups.

Actual compensation will depend on a candidate’s education, experience, skills, and geographic location. The anticipated wage for this position is

$64,500 - $167,200

Full-time equivalent employees also will be eligible for a company bonus (depending, in part, on company and individual performance). In addition, Lilly offers a comprehensive benefit program to eligible employees, including eligibility to participate in a company-sponsored 401(k); pension; vacation benefits; eligibility for medical, dental, vision and prescription drug benefits; flexible benefits (e.g., healthcare and/or dependent day care flexible spending accounts); life insurance and death benefits; certain time off and leave of absence benefits; and well-being benefits (e.g., employee assistance program, fitness benefits, and employee clubs and activities).Lilly reserves the right to amend, modify, or terminate its compensation and benefit programs in its sole discretion and Lilly’s compensation practices and guidelines will apply regarding the details of any promotion or transfer of Lilly employees.

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