Process Engineer - Day Shift

AstraZeneca GmbH; Coppell (TX); On-site; USD 90,000 - 120,000; Full time

Job summary

AstraZeneca GmbH in Coppell, TX is seeking a Process Engineer for a 12-hour day shift (5am–5pm) on a rotating schedule. You will lead process improvements, ensure GMP compliance, and support scale-up from development to production.

Qualifications include a BS in Chemical Engineering and 1–2 years in pharma or GMP settings, with skills in reading P&IDs, data analysis, and cross-functional collaboration. Join a safety-focused, collaborative team.

Qualifications

• Bachelor of Science in Chemical Engineering or related technical discipline with processing experience in pharma.
• 1–2 years of pharmaceutical production or GMP-regulated experience.
• Ability to read P&IDs and Process Flow Diagrams; perform mass and energy balances.
• Strong verbal and written communication; collaborative team player.
• Willingness to learn and apply analytical thinking.

Responsibilities

• Lead process improvements and optimize safety, quality, yield, and material use.
• Develop and refine process concepts, PFDs, and scopes of work.
• Coordinate with contractors on facility buildout and expansion.
• Assist in control strategy design, instrumentation, and automation.
• Write procedures, study proposals, and technical memos.
• Support validation activities (IQ/OQ/PQ/PPQ) and commissioning.
• Work on scale-up from R&D to production; troubleshoot deviations.

Skills

Process engineering

Data analysis

Quality assurance

Project management

Root cause analysis

Technical writing

GMP knowledge

Education

Bachelor of Science in Chemical Engineering

Tools

OSIsoft PI

SCADA

DCS

FactoryTalk

AVEVA/Wonderware SCADA

Minitab

TrackWise

Job description

Welcome to Coppell, Texas, one of over 400 sites here at AstraZeneca, providing a collaborative environment where everyone feels comfortable and able to be themselves is at the core of AstraZeneca’s priorities, it’s meaningful to us that you bring your full self to work every day.

THIS IS A 12 HOUR DAY SHIFT ROTATING POSITION WORKING 5am-5pm Day Shift - Process Engineer Shift coverage: 5am to 5pm shift- Ability to work 12-hour rotating shifts (2 days-on, 2 days-off, 3 days on, 2 days-off) working every other weekend per this rotation.

What you’ll do:

• Ethical conduct and compliance and adhering to AstraZeneca values and behaviors
• Become an expert on the process and equipment to successfully lead and implement processimprovements
• Develops conceptual strategies, processing schemes, feasibility studies, PFD’s, and detailedscopes of work
• Identify and implement projects to increase safety, reduce product cost, improve product quality,improve yield, and reduce material usage
• Work on several different projects and be able to prioritize these projects
• Works with contractors and project teams on the buildout and expansion of the facility whiledemonstrating confidence in voicing concerns and driving the project team to deliver a usableproduct for the end internal customer
• Assists in developing control strategy and instrument process design, including emergency andshutdown procedures, instrument specification sheets, control ranges, alarm points, andautomation strategy
• Authors, updates, reviews, and approves area procedures and master batch records to ensureaccurate content and compliance with Good Manufacturing Practices
• Designs studies, implements experiments and performs data analysis
• Writes study proposals, progress reports, development reports, and various technical memo’s
• Evaluates new technologies to improve the commercial production process
• Supports scale-up activities from R&D to production
• Supports the assurance of a robust manufacturing process for the current registered process asexperience is gained post-launch.
• Acts as an effective change agent
• Acts as a key player for the expansion of projects as needed to increase the scale ofmanufacture
• Investigate deviations from standards of the manufacturing process using effective root causeanalysis tools. Recommending and implementing effective corrective and preventative actions
• Generate, evaluate, and implement innovative and creative solutions
• Assist as subject matter expert for technical projects
• Capable of generating a project scope and cost plan to effectively draft a capital request

Domain knowledge:

Familiarity with pharmaceutical batch manufacturing processes preferred, other industries experience will be considered based on transferable chemical engineering principles and experience/ abilities. Experience with batch reactors, agitation systems, filter dryers, filtration, acids/base reactions, solids/API handling and bulk packing equipment, vacuum transfer systems, vacuum pumps, heat exchangers, condensers, and pulse-jet filters, water purification systems.

Technical writing and analysis:

Strong ability to rapidly assess trends and data and develop impact assessments addressing risks to quality, safety, and production KPIs.

Automation and SCADA:

Experience with PLC and SCADA or DCS control systems ( operational/engineering level). Preferred with FactoryTalk Rockwell Automation Platform and AVEVA/Wonderware SCADA.

Data historian:

Familiarity with OSIsoft PI Data Historian and PI Process Book preferred or similar process data trending software.

Qualification/validation: Experience executing or supporting IQ, OQ, PQ, and PPQ, commissioning, dry-runs for activities for new systems/equipment.

Minimum requirements:

• Bachelor of Science degree in Chemical Engineering or other relatedtechnical discipline with direct chemical processing experiencepreferably in a pharmaceutical production environment.
• 1-2 years experience preferably in a pharmaceutical production environment or GMP regulated environment.
• Ability to read P&ID’s, Process Flow Diagrams, and perform mass andenergy balances.
• Excellent verbal, written, and interpersonal communication skills areessential.
• Displays a high desire to learn while recognizing one's ownlimitations.
• Able to demonstrate technical capabilities using logical thoughtprocesses to analyze information and draw conclusions.

Desirable:

• High temperature andhigh-pressure applications
• Experience with pressurefilter dryer technology
• Experience with rootcause investigations
• Lean certification orexperience with leanconcepts
• Experience with Minitaband/or Trackwise

Date Posted: 21-Sep-2026

Closing Date: 18-Oct-2026

Our mission is to build an inclusive environment where equal employment opportunities are available to all applicants and employees. In furtherance of that mission, we welcome and consider applications from all qualified candidates, regardless of their protected characteristics. If you have a disability or special need that requires accommodation, please complete the corresponding section in the application form.