Production Technician I/II/III - Days

AstraZeneca; Frederick (MD); On-site; USD 56,000 - 84,000; Full time

Job summary

AstraZeneca's Frederick Manufacturing Center is hiring Production Technician I–III to operate processing equipment in a 12-hour rotating day shift (6 AM–6:30 PM). Roles require following cGMP/SOPs, preparing solutions, cell culture, purification and formulation, with MES documentation and ongoing training to advance through Tech I–III.

Applicants should have 0–3 years experience varying by level, and possess computer skills; degrees may substitute for experience at higher levels.

Qualifications

• Understanding of cGMP standards and SOPs.
• Ability to operate processing equipment and follow instructions.
• Strong computer skills and ability to work in teams.

Responsibilities

• Operate processing equipment per SOPs, MPRs and SPRs under cGMP.
• Prepare solutions, handle cell culture, purification and formulation tasks.
• Train with a qualified technician to become fully qualified on the line.
• Execute cGMP documentation and use MES for manufacturing records.
• Participate in problem solving and continuous improvement on the production floor.

Skills

Team collaboration

Attention to detail

Computer skills

Instruction following

Education

High School Diploma

Associate's degree

Bachelor's degree

Tools

MES

Bioprocessing equipment

Job description

Our Frederick Manufacturing Center (FMC) creates life-changing medicines for people around the world and has been recognized by our local community as being a Top 50’ Business in Frederick and awarded Frederick County’s ‘Best Place to Work’. This distinctive biologic manufacturing facility, with over 800 employees, makes a direct contribution to treating people with cancer, respiratory and autoimmune conditions across the globe. We work hard to deliver life-changing medicines to patients, and we take time to have fun and celebrate our accomplishments. From catered site festivities to competitive events, community outreach activities, environmental and wellness showcases and team-building functions, we take time to recognize our achievements and celebrate our diversity. We are dedicated to creating a culture of inclusion and collaboration and are committed to continuous learning by offering ongoing skill building and training for our staff. Fueled by our aspiration to deliver accelerated growth for our company and to make people’s lives better, there’s never been a more exciting time to join the team and shape the future of AstraZeneca Operations.

Are you ready to break new ground and leave a collective legacy?

As a Production Technician I at AstraZeneca, you will have the opportunity to play a pivotal role in evolving our Supply Chain. You will be operating upstream / downstream / central services processing equipment according to established SOPs. This is your chance to be part of a team that’s reimagining how we do things and creating a collective legacy.

Working Hours

This role is a 12 hour rotating day shift, 6AM to 6:30PM

Accountabilities

In this role, you will be responsible for the operation of processing equipment according to established SOPs, MPRs, & SPRs in accordance with cGMPs. Your duties will include solution preparation, cell culture, purification & formulation, and supporting activities. You will also train with a qualified Technician on activities related to operating process equipment with the requirement of qualification. Additionally, you will follow and execute cGMP documentation, utilize Manufacturing Execution systems (MES), contribute to problem-solving activities for non-routine activities on the production floor, and participate in continuous improvement activities for Manufacturing. Adherence to AstraZeneca values and behaviors is expected.

Essential Skills/Experience: Production Tech I

• 0-1 yrs experience with High School Diploma- Ability to work independently or in collaboration with others on assigned tasks- Ability to comply with cGMP standards- Must possess computer skills
• Ability to follow instruction and directions

Essential Skills/Experience: Production Tech II

• 0-1 years experience with Bachelors, >1 year with Associates, >2 years with High School Diploma
• Ability to work independently or in collaboration with others on assigned tasks
• Ability to follow cGMP standards
• Must possess computer skills
• Ability to follow instruction and directions
• Prior experience with aseptic/cGMP standards
• Prior experience in Bioprocessing work environment/systems/equipment operation

Essential Skills/Experience: Production Tech III

• 1-2 years experience with Bachelors, >2 year with Associates, >3 years with High School Diploma
• Ability to work independently or in collaboration with others on assigned tasks
• Ability to follow cGMP standards
• Possess computer skills
• Ability to follow instruction and directions
• Ability to perform job responsibilities with minimal oversight
• Prior experience with aseptic/cGMP standards
• Advanced prior experience in Bioprocessing work environment/systems/equipment operation
• BS/BA degree preferred

Desirable Skills/Experience

• BS/BA degree preferred
• Degree in STEM field
• Prior experience or exposure with aseptic/cGMP standards and environment

At AstraZeneca, we are driven by the challenge to stay ahead in rapidly changing markets. We continuously seek new and better ways to deliver medicines all the way to our patients. Our resilience helps us thrive as we innovate and evolve. We foster a safe and positive space where ideas are welcomed and rewarded. If you are self-driven, thrive at pace, continuously learning, and proactively taking on more, then this is the place for you.

Ready to make an impact? Join our Operations team today and contribute to life-changing medicines.

The annual base pay (or hourly rate of compensation) for this position ranges from $56,0720.00 to $84,108.00 Hourly and salaried non-exempt employees will also be paid overtime pay when working qualifying overtime hours. Base pay offered may vary depending on multiple individualized factors, including market location, job-related knowledge, skills, and experience. In addition, our positions offer a short-term incentive bonus opportunity; eligibility to participate in our equity-based long-term incentive program (salaried roles), to receive a retirement contribution (hourly roles), and commission payment eligibility (sales roles). Benefits offered included a qualified retirement program [401(k) plan]; paid vacation and holidays; paid leaves; and, health benefits including medical, prescription drug, dental, and vision coverage in accordance with the terms and conditions of the applicable plans. Additional details of participation in these benefit plans will be provided if an employee receives an offer of employment. If hired, employee will be in an “at-will position” and the Company reserves the right to modify base pay (as well as any other discretionary payment or compensation program) at any time, including for reasons related to individual performance, Company or individual department/team performance, and market factors.

Date Posted 10-Sep-2026

Closing Date 30-Sep-2026

Our mission is to build an inclusive environment where equal employment opportunities are available to all applicants and employees. In furtherance of that mission, we welcome and consider applications from all qualified candidates, regardless of their protected characteristics. If you have a disability or special need that requires accommodation, please complete the corresponding section in the application form.